Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Piperacillin> ?p ?o }
- Piperacillin abstract "Piperacillin is an antibiotic. It is an extended-spectrum beta-lactam of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into Gram-(-) bacteria and reduces susceptibility to cleavage by Gram-(-) beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa. Thus piperacillin is sometimes referred to as an "anti-pseudomonal penicillin".When used alone, piperacillin lacks strong activity against the Gram-(+) pathogen Staphylococcus aureus, as the beta-lactam ring is broken by the Gram-(+) beta lactamases.Piperacillin is most commonly used in combination with the beta-lactamase inhibitor tazobactam (piperacillin/tazobactam) (tradename "Zosyn"), which enhances piperacillin's effectiveness by inhibiting many beta lactamases to which it is susceptible. The co-administration of tazobactam does not confer activity against methicillin-resistant Staphylococcus aureus, however, as penicillins (and most other beta lactams) do not avidly bind to the penicillin-binding proteins of this pathogen.".
- Piperacillin atcPrefix "J01".
- Piperacillin atcSuffix "CA12".
- Piperacillin bioavailability "0.0".
- Piperacillin casNumber "61477-96-1".
- Piperacillin chEBI "8232".
- Piperacillin drugbank "DB00319".
- Piperacillin fdaUniiCode "9I628532GX".
- Piperacillin iupacName "(2S,5R,6R)-6-{[(2R)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid".
- Piperacillin pubchem "43672".
- Piperacillin thumbnail Piperacillin.svg?width=300.
- Piperacillin wikiPageID "2322131".
- Piperacillin wikiPageLength "7803".
- Piperacillin wikiPageOutDegree "20".
- Piperacillin wikiPageRevisionID "682056423".
- Piperacillin wikiPageWikiLink Antibiotic.
- Piperacillin wikiPageWikiLink Antibiotics.
- Piperacillin wikiPageWikiLink Beta-lactamase.
- Piperacillin wikiPageWikiLink Beta_lactamase.
- Piperacillin wikiPageWikiLink Category:Aromatic_compounds.
- Piperacillin wikiPageWikiLink Category:Beta-lactam_antibiotics.
- Piperacillin wikiPageWikiLink Category:Carboxylic_acids.
- Piperacillin wikiPageWikiLink Category:Diketopiperazines.
- Piperacillin wikiPageWikiLink Category:Enantiopure_drugs.
- Piperacillin wikiPageWikiLink Category:Wyeth.
- Piperacillin wikiPageWikiLink Extended-spectrum_penicillin.
- Piperacillin wikiPageWikiLink Intramuscular_injection.
- Piperacillin wikiPageWikiLink Intravenous_therapy.
- Piperacillin wikiPageWikiLink Methicillin-resistant_Staphylococcus_aureus.
- Piperacillin wikiPageWikiLink Minimum_inhibitory_concentration.
- Piperacillin wikiPageWikiLink National_Institute_for_Health_and_Care_Excellence.
- Piperacillin wikiPageWikiLink tazobactam.
- Piperacillin wikiPageWikiLink Ureidopenicillin.
- Piperacillin wikiPageWikiLink Β-Lactam_antibiotic.
- Piperacillin wikiPageWikiLink Β-Lactamase_inhibitor.
- Piperacillin wikiPageWikiLink Β-lactam_antibiotic.
- Piperacillin wikiPageWikiLinkText "Piperacillin".
- Piperacillin wikiPageWikiLinkText "Piperacillin-sulbactam".
- Piperacillin wikiPageWikiLinkText "piperacillin".
- Piperacillin wikiPageWikiLinkText "piperacillin/tazobactam".
- Piperacillin atcPrefix "J01".
- Piperacillin atcSuffix "CA12".
- Piperacillin bioavailability "0".
- Piperacillin c "23".
- Piperacillin casNumber "61477".
- Piperacillin chebi "8232".
- Piperacillin chembl "702".
- Piperacillin chemspiderid "39798".
- Piperacillin drugbank "DB00319".
- Piperacillin eliminationHalfLife "-4320.0".
- Piperacillin excretion "20".
- Piperacillin h "27".
- Piperacillin hasPhotoCollection Piperacillin.
- Piperacillin inchi "1".
- Piperacillin inchikey "IVBHGBMCVLDMKU-GXNBUGAJBB".
- Piperacillin iupacName "-6".
- Piperacillin iupharLigand "422".
- Piperacillin kegg "D08380".
- Piperacillin legalUk "POM".
- Piperacillin legalUs "Rx".
- Piperacillin metabolism "largely not metabolized".
- Piperacillin molecularWeight "517.555".
- Piperacillin n "5".
- Piperacillin o "7".
- Piperacillin pregnancyCategory "B".
- Piperacillin proteinBound "Slightly less than Amoxicillin".
- Piperacillin pubchem "43672".
- Piperacillin routesOfAdministration Intramuscular_injection.
- Piperacillin routesOfAdministration Intravenous_therapy.
- Piperacillin s "1".
- Piperacillin smiles "O=C[C@@H]3N4C[C@@H][C@H]4SC3C".
- Piperacillin stdinchi "1".
- Piperacillin stdinchikey "IVBHGBMCVLDMKU-GXNBUGAJSA-N".
- Piperacillin tradename "Pipracil".
- Piperacillin unii "9".
- Piperacillin verifiedrevid "461746289".
- Piperacillin wikiPageUsesTemplate Template:Drugbox.
- Piperacillin wikiPageUsesTemplate Template:PenicillinAntiBiotics.
- Piperacillin wikiPageUsesTemplate Template:Reflist.
- Piperacillin subject Category:Aromatic_compounds.
- Piperacillin subject Category:Beta-lactam_antibiotics.
- Piperacillin subject Category:Carboxylic_acids.
- Piperacillin subject Category:Diketopiperazines.
- Piperacillin subject Category:Enantiopure_drugs.
- Piperacillin subject Category:Wyeth.
- Piperacillin hypernym Antibiotic.
- Piperacillin type ChemicalSubstance.
- Piperacillin type Company.
- Piperacillin type Drug.
- Piperacillin type Company.
- Piperacillin type Drug.
- Piperacillin type Heterocycle.
- Piperacillin type Lactam.
- Piperacillin type ChemicalObject.
- Piperacillin type Thing.
- Piperacillin type Q8386.
- Piperacillin comment "Piperacillin is an antibiotic. It is an extended-spectrum beta-lactam of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into Gram-(-) bacteria and reduces susceptibility to cleavage by Gram-(-) beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa.".
- Piperacillin label "Piperacillin".
- Piperacillin sameAs Piperacillin.
- Piperacillin sameAs Piperacillin.