Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Phoebus_Levene> ?p ?o }
- Phoebus_Levene abstract "Phoebus Aaron Theodore Levene, M.D. (25 February 1863 – 6 September 1940) was an American biochemist who studied the structure and function of nucleic acids. He characterized the different forms of nucleic acid, DNA from RNA, and found that DNA contained adenine, guanine, thymine, cytosine, deoxyribose, and a phosphate group.He was born into a Litvak (Lithuanian Jewish) family as Fishel Aaronovich Levin in the town of Žagarė in Lithuania, then part of the Russian Empire, but grew up in St. Petersburg. There he studied medicine at the Imperial Military Medical Academy (M.D., 1891) and developed an interest in biochemistry. In 1893, because of anti-Semitic pogroms, he and his family emigrated to the United States and he practiced medicine in New York.Levene enrolled at Columbia University and in his spare time conducted biochemical research, publishing papers on the chemical structure of sugars. In 1896 he was appointed as an Associate in the Pathological Institute of the New York State Hospitals, but he had to take time off to recuperate from tuberculosis. During this period, he worked with several chemists, including Albrecht Kossel and Emil Fischer, who were the experts in proteins. In 1905, Levene was appointed as head of the biochemical laboratory at the Rockefeller Institute of Medical Research. He spent the rest of his career at this institute, and it was there that he identified the components of DNA. (He had discovered ribose in 1909 and deoxyribose in 1929.) Not only did Levene identify the components of DNA, he also showed that the components were linked together in the order phosphate-sugar-base to form units. He called each of these units a nucleotide, and stated that the DNA molecule consisted of a string of nucleotide units linked together through the phosphate groups, which are the 'backbone' of the molecule. His ideas about the structure of DNA were wrong; he thought there were only four nucleotides per molecule. He even declared that it could not store the genetic code because it was chemically far too simple. However, his work was a key basis for the later work that determined the structure of DNA. Levene published over 700 original papers and articles on biochemical structures. Levene died in 1940, before the true significance of DNA became clear. Levene is known for his "tetranucleotide hypothesis" (formulated around 1910) which first proposed that DNA was made up of equal amounts of adenine, guanine, cytosine, and thymine. Before the later work of Erwin Chargaff, it was widely thought that DNA was organized into repeating "tetranucleotides" in a way that could not carry genetic information. Instead, the protein component of chromosomes was thought to be the basis of heredity; most research on the physical nature of the gene focused on proteins, and particularly enzymes and viruses, before the 1940s.".
- Phoebus_Levene birthDate "1869-02-25".
- Phoebus_Levene birthPlace Russian_Empire.
- Phoebus_Levene birthYear "1869".
- Phoebus_Levene deathDate "1940-09-06".
- Phoebus_Levene deathYear "1940".
- Phoebus_Levene thumbnail Levene.jpg?width=300.
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- Phoebus_Levene wikiPageRevisionID "663259196".
- Phoebus_Levene wikiPageWikiLink Adenine.
- Phoebus_Levene wikiPageWikiLink Albrecht_Kossel.
- Phoebus_Levene wikiPageWikiLink Biochemist.
- Phoebus_Levene wikiPageWikiLink Category:1869_births.
- Phoebus_Levene wikiPageWikiLink Category:1940_deaths.
- Phoebus_Levene wikiPageWikiLink Category:American_chemists.
- Phoebus_Levene wikiPageWikiLink Category:American_people_of_Lithuanian-Jewish_descent.
- Phoebus_Levene wikiPageWikiLink Category:American_people_of_Russian-Jewish_descent.
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- Phoebus_Levene wikiPageWikiLink Category:Imperial_Russian_emigrants_to_the_United_States.
- Phoebus_Levene wikiPageWikiLink Category:Jewish_American_scientists.
- Phoebus_Levene wikiPageWikiLink Category:Lithuanian_Jews.
- Phoebus_Levene wikiPageWikiLink Category:Russian_Jews.
- Phoebus_Levene wikiPageWikiLink Category:Russian_people_of_Lithuanian_descent.
- Phoebus_Levene wikiPageWikiLink Chromosome.
- Phoebus_Levene wikiPageWikiLink Columbia_University.
- Phoebus_Levene wikiPageWikiLink Cytosine.
- Phoebus_Levene wikiPageWikiLink DNA.
- Phoebus_Levene wikiPageWikiLink Deoxyribose.
- Phoebus_Levene wikiPageWikiLink Doctor_of_Medicine.
- Phoebus_Levene wikiPageWikiLink Enzyme.
- Phoebus_Levene wikiPageWikiLink Erwin_Chargaff.
- Phoebus_Levene wikiPageWikiLink Gene.
- Phoebus_Levene wikiPageWikiLink Guanine.
- Phoebus_Levene wikiPageWikiLink Hermann_Emil_Fischer.
- Phoebus_Levene wikiPageWikiLink Lithuania.
- Phoebus_Levene wikiPageWikiLink Lithuanian_Jews.
- Phoebus_Levene wikiPageWikiLink M.D..
- Phoebus_Levene wikiPageWikiLink New_York.
- Phoebus_Levene wikiPageWikiLink Nucleic_acid.
- Phoebus_Levene wikiPageWikiLink Nucleotide.
- Phoebus_Levene wikiPageWikiLink Phoebus_Levin.
- Phoebus_Levene wikiPageWikiLink Pogrom.
- Phoebus_Levene wikiPageWikiLink Protein.
- Phoebus_Levene wikiPageWikiLink RNA.
- Phoebus_Levene wikiPageWikiLink Ribose.
- Phoebus_Levene wikiPageWikiLink Russian_Empire.
- Phoebus_Levene wikiPageWikiLink Saint_Petersburg.
- Phoebus_Levene wikiPageWikiLink St._Petersburg.
- Phoebus_Levene wikiPageWikiLink Thymine.
- Phoebus_Levene wikiPageWikiLink Virus.
- Phoebus_Levene wikiPageWikiLink Žagarė.
- Phoebus_Levene wikiPageWikiLink File:Levene.jpg.
- Phoebus_Levene wikiPageWikiLink File:Tetranucleotide.png.
- Phoebus_Levene wikiPageWikiLinkText "Levene, Phoebus Aaron Theodor".
- Phoebus_Levene wikiPageWikiLinkText "Phoebus A. T. Levene".
- Phoebus_Levene wikiPageWikiLinkText "Phoebus Levene".
- Phoebus_Levene wikiPageWikiLinkText "Phoebus Levene's".
- Phoebus_Levene dateOfBirth "1869-02-25".
- Phoebus_Levene dateOfDeath "1940-09-06".
- Phoebus_Levene hasPhotoCollection Phoebus_Levene.
- Phoebus_Levene name "Levene, Phoebus".
- Phoebus_Levene placeOfBirth "Russian Empire".
- Phoebus_Levene placeOfDeath "New York City".
- Phoebus_Levene shortDescription "American chemist".
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- Phoebus_Levene description "American chemist".
- Phoebus_Levene description "American chemist".
- Phoebus_Levene subject Category:1869_births.
- Phoebus_Levene subject Category:1940_deaths.
- Phoebus_Levene subject Category:American_chemists.
- Phoebus_Levene subject Category:American_people_of_Lithuanian-Jewish_descent.
- Phoebus_Levene subject Category:American_people_of_Russian-Jewish_descent.
- Phoebus_Levene subject Category:American_physicians.
- Phoebus_Levene subject Category:Imperial_Russian_emigrants_to_the_United_States.
- Phoebus_Levene subject Category:Jewish_American_scientists.
- Phoebus_Levene subject Category:Lithuanian_Jews.
- Phoebus_Levene subject Category:Russian_Jews.
- Phoebus_Levene subject Category:Russian_people_of_Lithuanian_descent.
- Phoebus_Levene hypernym Biochemist.
- Phoebus_Levene type Agent.
- Phoebus_Levene type Article.
- Phoebus_Levene type Person.
- Phoebus_Levene type Scientist.
- Phoebus_Levene type Article.
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