Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/PTTG1> ?p ?o }
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- PTTG1 abstract "Securin is a protein that in humans is encoded by the PTTG1 gene.The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.".
- PTTG1 entrezgene "9232".
- PTTG1 wikiPageID "14723782".
- PTTG1 wikiPageLength "12134".
- PTTG1 wikiPageOutDegree "8".
- PTTG1 wikiPageRevisionID "673310119".
- PTTG1 wikiPageWikiLink DNAJA1.
- PTTG1 wikiPageWikiLink Gene.
- PTTG1 wikiPageWikiLink Ku70.
- PTTG1 wikiPageWikiLink P53.
- PTTG1 wikiPageWikiLink PTTG1IP.
- PTTG1 wikiPageWikiLink Protein.
- PTTG1 wikiPageWikiLink Protein-protein_interaction.
- PTTG1 wikiPageWikiLink Protein–protein_interaction.
- PTTG1 wikiPageWikiLink RPS10.
- PTTG1 wikiPageWikiLinkText "PTTG1".
- PTTG1 hasPhotoCollection PTTG1.
- PTTG1 requireManualInspection "no".
- PTTG1 summaryText "The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.".
- PTTG1 updateCitations "yes".
- PTTG1 updatePage "yes".
- PTTG1 updateProteinBox "yes".
- PTTG1 updateSummary "yes".
- PTTG1 wikiPageUsesTemplate Template:Gene-5-stub.
- PTTG1 wikiPageUsesTemplate Template:PBB.
- PTTG1 wikiPageUsesTemplate Template:PBB_Controls.
- PTTG1 wikiPageUsesTemplate Template:PBB_Further_reading.
- PTTG1 wikiPageUsesTemplate Template:PBB_Summary.
- PTTG1 wikiPageUsesTemplate Template:Refbegin.
- PTTG1 wikiPageUsesTemplate Template:Refend.
- PTTG1 wikiPageUsesTemplate Template:Reflist.
- PTTG1 hypernym Protein.
- PTTG1 type Article.
- PTTG1 type Biomolecule.
- PTTG1 type Protein.
- PTTG1 type Article.
- PTTG1 type Thing.
- PTTG1 type Q206229.
- PTTG1 type Q8054.
- PTTG1 comment "Securin is a protein that in humans is encoded by the PTTG1 gene.The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors.".
- PTTG1 label "PTTG1".
- PTTG1 sameAs PTTG1.
- PTTG1 sameAs m.03gvlmp.
- PTTG1 sameAs Q7121045.
- PTTG1 sameAs Q7121045.
- PTTG1 wasDerivedFrom PTTG1?oldid=673310119.
- PTTG1 isPrimaryTopicOf PTTG1.