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- PTPN13 abstract "Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.".
- PTPN13 entrezgene "5783".
- PTPN13 wikiPageID "14726062".
- PTPN13 wikiPageLength "11091".
- PTPN13 wikiPageOutDegree "16".
- PTPN13 wikiPageRevisionID "675573630".
- PTPN13 wikiPageWikiLink C-terminus.
- PTPN13 wikiPageWikiLink Carcinogenesis.
- PTPN13 wikiPageWikiLink Cell_growth.
- PTPN13 wikiPageWikiLink Cell_signaling.
- PTPN13 wikiPageWikiLink Cellular_differentiation.
- PTPN13 wikiPageWikiLink Cytoskeletal.
- PTPN13 wikiPageWikiLink Cytoskeleton.
- PTPN13 wikiPageWikiLink Enzyme.
- PTPN13 wikiPageWikiLink Fas_receptor.
- PTPN13 wikiPageWikiLink Gene.
- PTPN13 wikiPageWikiLink Leucine_zipper.
- PTPN13 wikiPageWikiLink Mitosis.
- PTPN13 wikiPageWikiLink Oncogenic.
- PTPN13 wikiPageWikiLink PDZ_domain.
- PTPN13 wikiPageWikiLink PKN2.
- PTPN13 wikiPageWikiLink Protein-protein_interaction.
- PTPN13 wikiPageWikiLink Protein_tyrosine_phosphatase.
- PTPN13 wikiPageWikiLink Protein–protein_interaction.
- PTPN13 wikiPageWikiLink Rho_factor.
- PTPN13 wikiPageWikiLink Signaling_molecules.
- PTPN13 wikiPageWikiLinkText "PTP-BL".
- PTPN13 wikiPageWikiLinkText "PTPN13".
- PTPN13 hasPhotoCollection PTPN13.
- PTPN13 requireManualInspection "no".
- PTPN13 summaryText "The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.".
- PTPN13 updateCitations "yes".
- PTPN13 updatePage "yes".
- PTPN13 updateProteinBox "yes".
- PTPN13 updateSummary "yes".
- PTPN13 wikiPageUsesTemplate Template:Gene-4-stub.
- PTPN13 wikiPageUsesTemplate Template:PBB.
- PTPN13 wikiPageUsesTemplate Template:PBB_Controls.
- PTPN13 wikiPageUsesTemplate Template:PBB_Further_reading.
- PTPN13 wikiPageUsesTemplate Template:PBB_Summary.
- PTPN13 wikiPageUsesTemplate Template:PDB_Gallery.
- PTPN13 wikiPageUsesTemplate Template:Protein_tyrosine_phosphatases.
- PTPN13 wikiPageUsesTemplate Template:Refbegin.
- PTPN13 wikiPageUsesTemplate Template:Refend.
- PTPN13 wikiPageUsesTemplate Template:Reflist.
- PTPN13 hypernym Enzyme.
- PTPN13 type Biomolecule.
- PTPN13 type Protein.
- PTPN13 type Thing.
- PTPN13 type Q206229.
- PTPN13 type Q8054.
- PTPN13 comment "Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.".
- PTPN13 label "PTPN13".
- PTPN13 sameAs m.03gvpx7.
- PTPN13 sameAs Q7120999.
- PTPN13 sameAs Q7120999.
- PTPN13 wasDerivedFrom PTPN13?oldid=675573630.
- PTPN13 isPrimaryTopicOf PTPN13.