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- PTPN12 abstract "Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein–protein interaction domain, and may be related to protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of oncogene c-ABL, thus may play a role in oncogenesis. This PTP was shown to interact with, and dephosphorylate, various of cytoskeleton and cell adhesion molecules, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin, which suggested its regulatory roles in controlling cell shape and mobility.".
- PTPN12 entrezgene "5782".
- PTPN12 wikiPageID "14725645".
- PTPN12 wikiPageLength "15039".
- PTPN12 wikiPageOutDegree "9".
- PTPN12 wikiPageRevisionID "679005453".
- PTPN12 wikiPageWikiLink BCAR1.
- PTPN12 wikiPageWikiLink Enzyme.
- PTPN12 wikiPageWikiLink GRB2.
- PTPN12 wikiPageWikiLink Gene.
- PTPN12 wikiPageWikiLink Grb2.
- PTPN12 wikiPageWikiLink PSTPIP1.
- PTPN12 wikiPageWikiLink Paxillin.
- PTPN12 wikiPageWikiLink Protein–protein_interaction.
- PTPN12 wikiPageWikiLink SHC1.
- PTPN12 wikiPageWikiLink TGFB1I1.
- PTPN12 wikiPageWikiLinkText "PTP-PEST".
- PTPN12 wikiPageWikiLinkText "PTPN12".
- PTPN12 wikiPageWikiLinkText "protein tyrosine phosphatase-PEST".
- PTPN12 hasPhotoCollection PTPN12.
- PTPN12 requireManualInspection "no".
- PTPN12 summaryText "The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein–protein interaction domain, and may be related to protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of oncogene c-ABL, thus may play a role in oncogenesis. This PTP was shown to interact with, and dephosphorylate, various of cytoskeleton and cell adhesion molecules, such as p130 , CAKbeta/PTK2B, PSTPIP1, and paxillin, which suggested its regulatory roles in controlling cell shape and mobility.".
- PTPN12 updateCitations "yes".
- PTPN12 updatePage "yes".
- PTPN12 updateProteinBox "yes".
- PTPN12 updateSummary "yes".
- PTPN12 wikiPageUsesTemplate Template:Gene-7-stub.
- PTPN12 wikiPageUsesTemplate Template:PBB.
- PTPN12 wikiPageUsesTemplate Template:PBB_Controls.
- PTPN12 wikiPageUsesTemplate Template:PBB_Further_reading.
- PTPN12 wikiPageUsesTemplate Template:PBB_Summary.
- PTPN12 wikiPageUsesTemplate Template:Protein_tyrosine_phosphatases.
- PTPN12 wikiPageUsesTemplate Template:Refbegin.
- PTPN12 wikiPageUsesTemplate Template:Refend.
- PTPN12 wikiPageUsesTemplate Template:Reflist.
- PTPN12 wikiPageUsesTemplate Template:Use_mdy_dates.
- PTPN12 hypernym Enzyme.
- PTPN12 type Biomolecule.
- PTPN12 type Protein.
- PTPN12 type Thing.
- PTPN12 type Q206229.
- PTPN12 type Q8054.
- PTPN12 comment "Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.".
- PTPN12 label "PTPN12".
- PTPN12 sameAs m.03gvn_q.
- PTPN12 sameAs Q7120998.
- PTPN12 sameAs Q7120998.
- PTPN12 wasDerivedFrom PTPN12?oldid=679005453.
- PTPN12 isPrimaryTopicOf PTPN12.