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- PDK4 abstract "Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme of pyruvate dehydrogenase kinase.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, reducing the conversion of pyruvate, which is produced from the oxidation of glucose and amino acids, to acetyl-CoA and contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. PDK4 is increased in hibernation and helps to decrease metabolism and conserve glucose by decreasing its conversion to acetyl-CoA, which enters the citric acid cycle and is converted to ATP.".
- PDK4 entrezgene "5166".
- PDK4 wikiPageID "14758053".
- PDK4 wikiPageLength "19250".
- PDK4 wikiPageOutDegree "28".
- PDK4 wikiPageRevisionID "674200235".
- PDK4 wikiPageWikiLink Acetyl-CoA.
- PDK4 wikiPageWikiLink Adenosine_triphosphate.
- PDK4 wikiPageWikiLink Amino_acid.
- PDK4 wikiPageWikiLink Beta_oxidation.
- PDK4 wikiPageWikiLink Carbohydrate_metabolism.
- PDK4 wikiPageWikiLink Citric_acid_cycle.
- PDK4 wikiPageWikiLink Enzyme.
- PDK4 wikiPageWikiLink Farnesoid_X_receptor.
- PDK4 wikiPageWikiLink Fatty_acid_oxidation.
- PDK4 wikiPageWikiLink Gene.
- PDK4 wikiPageWikiLink Glucocorticoid.
- PDK4 wikiPageWikiLink Glucose.
- PDK4 wikiPageWikiLink Glucose_metabolism.
- PDK4 wikiPageWikiLink Hibernation.
- PDK4 wikiPageWikiLink Histidine.
- PDK4 wikiPageWikiLink Insulin.
- PDK4 wikiPageWikiLink Isozyme.
- PDK4 wikiPageWikiLink Lipoamide.
- PDK4 wikiPageWikiLink Metabolism.
- PDK4 wikiPageWikiLink Mitochondria.
- PDK4 wikiPageWikiLink Mitochondrial_matrix.
- PDK4 wikiPageWikiLink Mitochondrion.
- PDK4 wikiPageWikiLink PPARGC1A.
- PDK4 wikiPageWikiLink Peroxisome_proliferator-activated_receptor.
- PDK4 wikiPageWikiLink Peroxisome_proliferator-activated_receptors.
- PDK4 wikiPageWikiLink Phosphorylation.
- PDK4 wikiPageWikiLink Protein_kinase.
- PDK4 wikiPageWikiLink Pyruvate.
- PDK4 wikiPageWikiLink Pyruvate_dehydrogenase_complex.
- PDK4 wikiPageWikiLink Pyruvate_dehydrogenase_kinase.
- PDK4 wikiPageWikiLink Pyruvic_acid.
- PDK4 wikiPageWikiLink Retinoic_acid.
- PDK4 wikiPageWikiLink Rosiglitazone.
- PDK4 wikiPageWikiLinkText "PDK4".
- PDK4 hasPhotoCollection PDK4.
- PDK4 wikiPageUsesTemplate Template:Cite_journal.
- PDK4 wikiPageUsesTemplate Template:PBB.
- PDK4 wikiPageUsesTemplate Template:Refbegin.
- PDK4 wikiPageUsesTemplate Template:Refend.
- PDK4 wikiPageUsesTemplate Template:Reflist.
- PDK4 wikiPageUsesTemplate Template:TCACycle_WP78.
- PDK4 hypernym Enzyme.
- PDK4 type Biomolecule.
- PDK4 type Protein.
- PDK4 type Thing.
- PDK4 type Q206229.
- PDK4 type Q8054.
- PDK4 comment "Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme of pyruvate dehydrogenase kinase.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain.".
- PDK4 label "PDK4".
- PDK4 sameAs m.03gwy8l.
- PDK4 sameAs Q7118827.
- PDK4 sameAs Q7118827.
- PDK4 wasDerivedFrom PDK4?oldid=674200235.
- PDK4 isPrimaryTopicOf PDK4.