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- PD-L1 abstract "Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the immune system reacts to foreign antigens where there is some accumulation in the lymph nodes or spleen which triggers a proliferation of antigen-specific CD8+ T cell. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes and supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2.".
- PD-L1 entrezgene "29126".
- PD-L1 thumbnail B7_family_ligands_and_CD28_family_receptors.JPG?width=300.
- PD-L1 wikiPageID "14157278".
- PD-L1 wikiPageLength "13634".
- PD-L1 wikiPageOutDegree "50".
- PD-L1 wikiPageRevisionID "672631939".
- PD-L1 wikiPageWikiLink AP-1_transcription_factor.
- PD-L1 wikiPageWikiLink Allograft.
- PD-L1 wikiPageWikiLink Allotransplantation.
- PD-L1 wikiPageWikiLink Antigen.
- PD-L1 wikiPageWikiLink Bcl-2.
- PD-L1 wikiPageWikiLink CD247.
- PD-L1 wikiPageWikiLink CD28.
- PD-L1 wikiPageWikiLink CD80.
- PD-L1 wikiPageWikiLink CD86.
- PD-L1 wikiPageWikiLink CTLA-4.
- PD-L1 wikiPageWikiLink Category:Clusters_of_differentiation.
- PD-L1 wikiPageWikiLink Cholangiocyte.
- PD-L1 wikiPageWikiLink Cluster_of_differentiation.
- PD-L1 wikiPageWikiLink Co-stimulation.
- PD-L1 wikiPageWikiLink Cytotoxic_T_cell.
- PD-L1 wikiPageWikiLink Dendritic_cell.
- PD-L1 wikiPageWikiLink Dissociation_constant.
- PD-L1 wikiPageWikiLink Gene.
- PD-L1 wikiPageWikiLink IRF1.
- PD-L1 wikiPageWikiLink Immune_system.
- PD-L1 wikiPageWikiLink Immune_tolerance.
- PD-L1 wikiPageWikiLink Interferon-gamma.
- PD-L1 wikiPageWikiLink Interferon_gamma.
- PD-L1 wikiPageWikiLink Interferon_type_I.
- PD-L1 wikiPageWikiLink Interleukin_2.
- PD-L1 wikiPageWikiLink Interleukin_4.
- PD-L1 wikiPageWikiLink Lipopolysaccharide.
- PD-L1 wikiPageWikiLink Lung_cancer.
- PD-L1 wikiPageWikiLink Lymph_node.
- PD-L1 wikiPageWikiLink Macrophage.
- PD-L1 wikiPageWikiLink MicroRNA.
- PD-L1 wikiPageWikiLink Monocyte.
- PD-L1 wikiPageWikiLink Monocytes.
- PD-L1 wikiPageWikiLink NF-κB.
- PD-L1 wikiPageWikiLink NOD_mice.
- PD-L1 wikiPageWikiLink Ovarian_cancer.
- PD-L1 wikiPageWikiLink PBMC.
- PD-L1 wikiPageWikiLink PD-1.
- PD-L1 wikiPageWikiLink PDCD1LG2.
- PD-L1 wikiPageWikiLink PRKCQ.
- PD-L1 wikiPageWikiLink Peripheral_blood_mononuclear_cell.
- PD-L1 wikiPageWikiLink Programmed_cell_death_1.
- PD-L1 wikiPageWikiLink Protein.
- PD-L1 wikiPageWikiLink Renal_cell_carcinoma.
- PD-L1 wikiPageWikiLink STAT1.
- PD-L1 wikiPageWikiLink Systemic_lupus_erythematosus.
- PD-L1 wikiPageWikiLink T_cell_receptor.
- PD-L1 wikiPageWikiLink T_helper_cell.
- PD-L1 wikiPageWikiLink Transmembrane_protein.
- PD-L1 wikiPageWikiLink ZAP-70.
- PD-L1 wikiPageWikiLink ZAP70.
- PD-L1 wikiPageWikiLink File:B7_family_ligands_and_CD28_family_receptors.JPG.
- PD-L1 wikiPageWikiLinkText "B7-H1".
- PD-L1 wikiPageWikiLinkText "PD-L1".
- PD-L1 hasPhotoCollection PD-L1.
- PD-L1 requireManualInspection "no".
- PD-L1 updateCitations "yes".
- PD-L1 updatePage "yes".
- PD-L1 updateProteinBox "yes".
- PD-L1 updateSummary "yes".
- PD-L1 wikiPageUsesTemplate Template:B7_Family.
- PD-L1 wikiPageUsesTemplate Template:Clusters_of_differentiation.
- PD-L1 wikiPageUsesTemplate Template:MeshName.
- PD-L1 wikiPageUsesTemplate Template:PBB.
- PD-L1 wikiPageUsesTemplate Template:PBB_Controls.
- PD-L1 wikiPageUsesTemplate Template:Reflist.
- PD-L1 subject Category:Clusters_of_differentiation.
- PD-L1 hypernym Protein.
- PD-L1 type Article.
- PD-L1 type Biomolecule.
- PD-L1 type Protein.
- PD-L1 type Article.
- PD-L1 type Thing.
- PD-L1 type Q206229.
- PD-L1 type Q8054.
- PD-L1 comment "Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.".
- PD-L1 label "PD-L1".
- PD-L1 sameAs m.03cw9h1.
- PD-L1 sameAs Q7118744.
- PD-L1 sameAs Q7118744.
- PD-L1 sameAs 細胞程式死亡-配體1.
- PD-L1 wasDerivedFrom PD-L1?oldid=672631939.
- PD-L1 depiction B7_family_ligands_and_CD28_family_receptors.JPG.
- PD-L1 isPrimaryTopicOf PD-L1.