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- Olfactory_transduction abstract "Olfactory transduction is a series of events in which odor molecules are detected by olfactory receptors and chemical signals are transformed into electrical signal to the brain where they are perceived as smells.Once ligands (odorant particles) bind to specific receptors on the external surface of cilia, olfactory transduction is initiated. In mammals, olfactory receptors have been shown to signal via G protein. This is a similar type of signaling of other known G protein-coupled receptors (GPCR). The binding of an odorant particle on an olfactory receptor activates a particular G protein (Gαolf), which then activates adenylate cyclase, leading to cAMP production. cAMP then binds and opens Cyclic nucleotide-gated ion channel. This opening allows for an influx of both Na+ and Ca2+ ions into the cell, thus depolarizing it. The Ca2+ in turn activates chloride channels, causing efflux of Cl−, which results in a further depolarization of the cell.The odorant-activated cAMP cascade in the olfactory sensory neuron is subject to negative feedback regulation, like all other G-protein mediated pathways. This contributes to response deactivation and adaptation to stimulus.Individual odorants activate subsets of receptors. Receptors also have varying affinities for odorant molecules. In addition, higher concentrations of odorants elicit activity from greater a number of receptors than do lower concentrations. Thus, odor intensity as well as odor identity is represented by combination of a number of activated receptors.".
- Olfactory_transduction wikiPageExternalLink dictionary?CdrID=462728.
- Olfactory_transduction wikiPageID "16081258".
- Olfactory_transduction wikiPageLength "2722".
- Olfactory_transduction wikiPageOutDegree "13".
- Olfactory_transduction wikiPageRevisionID "679856888".
- Olfactory_transduction wikiPageWikiLink Adenylate_cyclase.
- Olfactory_transduction wikiPageWikiLink Category:G_protein_coupled_receptors.
- Olfactory_transduction wikiPageWikiLink Category:Integral_membrane_proteins.
- Olfactory_transduction wikiPageWikiLink Category:Neurophysiology.
- Olfactory_transduction wikiPageWikiLink Category:Olfactory_system.
- Olfactory_transduction wikiPageWikiLink Category:Protein_families.
- Olfactory_transduction wikiPageWikiLink Category:Sensory_receptors.
- Olfactory_transduction wikiPageWikiLink Cyclic_nucleotide-gated_ion_channel.
- Olfactory_transduction wikiPageWikiLink G-protein.
- Olfactory_transduction wikiPageWikiLink G_protein.
- Olfactory_transduction wikiPageWikiLink G_protein-coupled_receptors.
- Olfactory_transduction wikiPageWikiLink G_protein–coupled_receptor.
- Olfactory_transduction wikiPageWikiLink Olfactory_receptor.
- Olfactory_transduction wikiPageWikiLink Olfactory_receptor_neuron.
- Olfactory_transduction wikiPageWikiLink Olfactory_receptors.
- Olfactory_transduction wikiPageWikiLink Olfactory_sensory_neuron.
- Olfactory_transduction wikiPageWikiLinkText "Olfactory transduction".
- Olfactory_transduction wikiPageWikiLinkText "transduction".
- Olfactory_transduction hasPhotoCollection Olfactory_transduction.
- Olfactory_transduction wikiPageUsesTemplate Template:G_protein-coupled_receptors.
- Olfactory_transduction wikiPageUsesTemplate Template:NCI-cancer-dict.
- Olfactory_transduction wikiPageUsesTemplate Template:Neuroanatomy-stub.
- Olfactory_transduction wikiPageUsesTemplate Template:Olfactory_receptors.
- Olfactory_transduction wikiPageUsesTemplate Template:Olfactory_system.
- Olfactory_transduction wikiPageUsesTemplate Template:Transmembrane_receptors.
- Olfactory_transduction subject Category:G_protein_coupled_receptors.
- Olfactory_transduction subject Category:Integral_membrane_proteins.
- Olfactory_transduction subject Category:Neurophysiology.
- Olfactory_transduction subject Category:Olfactory_system.
- Olfactory_transduction subject Category:Protein_families.
- Olfactory_transduction subject Category:Sensory_receptors.
- Olfactory_transduction hypernym Series.
- Olfactory_transduction type Article.
- Olfactory_transduction type TelevisionShow.
- Olfactory_transduction type Article.
- Olfactory_transduction type Institute.
- Olfactory_transduction type Sensor.
- Olfactory_transduction type Source.
- Olfactory_transduction comment "Olfactory transduction is a series of events in which odor molecules are detected by olfactory receptors and chemical signals are transformed into electrical signal to the brain where they are perceived as smells.Once ligands (odorant particles) bind to specific receptors on the external surface of cilia, olfactory transduction is initiated. In mammals, olfactory receptors have been shown to signal via G protein.".
- Olfactory_transduction label "Olfactory transduction".
- Olfactory_transduction sameAs m.03qnknb.
- Olfactory_transduction sameAs Q7086514.
- Olfactory_transduction sameAs Q7086514.
- Olfactory_transduction wasDerivedFrom Olfactory_transduction?oldid=679856888.
- Olfactory_transduction isPrimaryTopicOf Olfactory_transduction.