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- OSU-6162 abstract "OSU-6162 (PNU-96391) is a compound which acts as a partial agonist at both dopamine D2 receptors and 5-HT2A receptors. It acts as a dopamine stabilizer in a similar manner to the closely related drug pridopidine, and has antipsychotic, anti-addictive and anti-Parkinsonian effects in animal studies. Both enantiomers show similar activity but with different ratios of effects, with the (S) enantiomer (–)-OSU-6162 that is more commonly used in research, having higher binding affinity to D2 but is a weaker partial agonist at 5-HT2A, while the (R) enantiomer (+)-OSU-6162 has higher efficacy at 5-HT2A but lower D2 affinity.".
- OSU-6162 atcPrefix "none".
- OSU-6162 casNumber "156907-84-5".
- OSU-6162 iupacName "(3S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine".
- OSU-6162 pubchem "9795741".
- OSU-6162 thumbnail OSU-6162_structure.png?width=300.
- OSU-6162 wikiPageID "34061192".
- OSU-6162 wikiPageLength "6971".
- OSU-6162 wikiPageOutDegree "15".
- OSU-6162 wikiPageRevisionID "678668247".
- OSU-6162 wikiPageWikiLink 5-HT2A_receptor.
- OSU-6162 wikiPageWikiLink Addiction.
- OSU-6162 wikiPageWikiLink Antipsychotic.
- OSU-6162 wikiPageWikiLink Binding_affinity.
- OSU-6162 wikiPageWikiLink Category:Amines.
- OSU-6162 wikiPageWikiLink Category:Dopamine_agonists.
- OSU-6162 wikiPageWikiLink Category:Neuropharmacology.
- OSU-6162 wikiPageWikiLink Category:Piperidines.
- OSU-6162 wikiPageWikiLink Category:Sulfones.
- OSU-6162 wikiPageWikiLink Dopamine_D2_receptor.
- OSU-6162 wikiPageWikiLink Dopamine_receptor_D2.
- OSU-6162 wikiPageWikiLink Drug_addiction.
- OSU-6162 wikiPageWikiLink Enantiomer.
- OSU-6162 wikiPageWikiLink Ligand_(biochemistry).
- OSU-6162 wikiPageWikiLink PF-219,061.
- OSU-6162 wikiPageWikiLink Parkinsons_disease.
- OSU-6162 wikiPageWikiLink Partial_agonist.
- OSU-6162 wikiPageWikiLink Pridopidine.
- OSU-6162 wikiPageWikiLinkText "OSU-6162".
- OSU-6162 atcPrefix "none".
- OSU-6162 c "15".
- OSU-6162 casNumber "156907".
- OSU-6162 chembl "311730".
- OSU-6162 chemspiderid "7971507".
- OSU-6162 h "23".
- OSU-6162 hasPhotoCollection OSU-6162.
- OSU-6162 inchi "1".
- OSU-6162 inchikey "GZVBVBMMNFIXGE-CQSZACIVBI".
- OSU-6162 iupacName "-3".
- OSU-6162 molecularWeight "281.413".
- OSU-6162 n "1".
- OSU-6162 o "2".
- OSU-6162 pubchem "9795741".
- OSU-6162 s "1".
- OSU-6162 smiles "CCCN1CCC[C@H]C2=CCSC".
- OSU-6162 stdinchi "1".
- OSU-6162 stdinchikey "GZVBVBMMNFIXGE-CQSZACIVSA-N".
- OSU-6162 width "220".
- OSU-6162 wikiPageUsesTemplate Template:Dopaminergics.
- OSU-6162 wikiPageUsesTemplate Template:Drugbox.
- OSU-6162 wikiPageUsesTemplate Template:Serotonergics.
- OSU-6162 subject Category:Amines.
- OSU-6162 subject Category:Dopamine_agonists.
- OSU-6162 subject Category:Neuropharmacology.
- OSU-6162 subject Category:Piperidines.
- OSU-6162 subject Category:Sulfones.
- OSU-6162 hypernym Compound.
- OSU-6162 type Agent.
- OSU-6162 type Article.
- OSU-6162 type ChemicalCompound.
- OSU-6162 type ChemicalSubstance.
- OSU-6162 type Drug.
- OSU-6162 type Group.
- OSU-6162 type Agent.
- OSU-6162 type Agonist.
- OSU-6162 type Article.
- OSU-6162 type Chemical.
- OSU-6162 type Drug.
- OSU-6162 type Group.
- OSU-6162 type Heterocycle.
- OSU-6162 type Science.
- OSU-6162 type ChemicalObject.
- OSU-6162 type Thing.
- OSU-6162 type Q8386.
- OSU-6162 comment "OSU-6162 (PNU-96391) is a compound which acts as a partial agonist at both dopamine D2 receptors and 5-HT2A receptors. It acts as a dopamine stabilizer in a similar manner to the closely related drug pridopidine, and has antipsychotic, anti-addictive and anti-Parkinsonian effects in animal studies.".
- OSU-6162 label "OSU-6162".
- OSU-6162 sameAs m.0hr4p0w.
- OSU-6162 sameAs OSU-6162.
- OSU-6162 sameAs OSU-6162.
- OSU-6162 sameAs OSU-6162.
- OSU-6162 sameAs Q6593699.
- OSU-6162 sameAs Q6593699.
- OSU-6162 wasDerivedFrom OSU-6162?oldid=678668247.
- OSU-6162 depiction OSU-6162_structure.png.
- OSU-6162 isPrimaryTopicOf OSU-6162.