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- OSI-7904L abstract "OSI-7904L is a novel noncompetitive liposomal thymidylate synthase inhibitor. OSI-7904 is a benzoquinazoline folate analog with antineoplastic activity. As a thymidylate synthase inhibitor, OSI-7904 noncompetitively binds to thymidylate synthase, resulting in inhibition of thymine nucleotide synthesis and DNA replication.OSI-7904L is a liposome-encapsulated formulation of OSI-7904. Liposome encapsulation improves the efficacy and increases the half-life of OSI-7904.Its effect on solid tumours is currently under evaluation.".
- OSI-7904L wikiPageID "21380025".
- OSI-7904L wikiPageLength "2004".
- OSI-7904L wikiPageOutDegree "11".
- OSI-7904L wikiPageRevisionID "678989794".
- OSI-7904L wikiPageWikiLink Antineoplastic.
- OSI-7904L wikiPageWikiLink Category:Cancer_research.
- OSI-7904L wikiPageWikiLink Chemotherapy.
- OSI-7904L wikiPageWikiLink DNA_replication.
- OSI-7904L wikiPageWikiLink Half-life.
- OSI-7904L wikiPageWikiLink Liposome.
- OSI-7904L wikiPageWikiLink Neoplasm.
- OSI-7904L wikiPageWikiLink Nucleotide.
- OSI-7904L wikiPageWikiLink Nucleotide_synthesis.
- OSI-7904L wikiPageWikiLink Solid_tumor.
- OSI-7904L wikiPageWikiLink Thymidylate_synthase.
- OSI-7904L wikiPageWikiLink Thymidylate_synthase_inhibitor.
- OSI-7904L wikiPageWikiLink Thymine.
- OSI-7904L wikiPageWikiLink Wikt:benzoquinazoline.
- OSI-7904L wikiPageWikiLinkText "OSI-7904L".
- OSI-7904L hasPhotoCollection OSI-7904L.
- OSI-7904L wikiPageUsesTemplate Template:Antineoplastic-drug-stub.
- OSI-7904L wikiPageUsesTemplate Template:Expert-subject.
- OSI-7904L wikiPageUsesTemplate Template:Reflist.
- OSI-7904L subject Category:Cancer_research.
- OSI-7904L hypernym Inhibitor.
- OSI-7904L type Article.
- OSI-7904L type ChemicalSubstance.
- OSI-7904L type Article.
- OSI-7904L comment "OSI-7904L is a novel noncompetitive liposomal thymidylate synthase inhibitor. OSI-7904 is a benzoquinazoline folate analog with antineoplastic activity. As a thymidylate synthase inhibitor, OSI-7904 noncompetitively binds to thymidylate synthase, resulting in inhibition of thymine nucleotide synthesis and DNA replication.OSI-7904L is a liposome-encapsulated formulation of OSI-7904.".
- OSI-7904L label "OSI-7904L".
- OSI-7904L sameAs m.05f4970.
- OSI-7904L sameAs Q7073016.
- OSI-7904L sameAs Q7073016.
- OSI-7904L wasDerivedFrom OSI-7904L?oldid=678989794.
- OSI-7904L isPrimaryTopicOf OSI-7904L.