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- O-1812 abstract "O-1812 is an eicosanoid derivative related to anandamide that acts as a potent and highly selective agonist for the cannabinoid receptor CB1, with a Ki of 3.4nM at CB1 and 3870nM at CB2. Unlike most related compounds, O-1812 is metabolically stable against rapid breakdown by enzymes, and produces a cannabinoid-like discriminative effect in rats, which is similar but not identical to that produced by cannabinoid drugs of other chemical classes.".
- O-1812 casNumber "342882-77-3".
- O-1812 iupacName "(5Z,8Z,11Z,14Z)-20-cyano-N-[(2R)-1-hydroxypropan-2-yl]-16,16-dimethylicosa-5,8,11,14-tetraenamide".
- O-1812 pubchem "9823107".
- O-1812 thumbnail O-1812_structure.png?width=300.
- O-1812 wikiPageID "32069457".
- O-1812 wikiPageLength "4608".
- O-1812 wikiPageOutDegree "15".
- O-1812 wikiPageRevisionID "678987597".
- O-1812 wikiPageWikiLink AM-1235.
- O-1812 wikiPageWikiLink AM-2232.
- O-1812 wikiPageWikiLink AM-2389.
- O-1812 wikiPageWikiLink Agonist.
- O-1812 wikiPageWikiLink Anandamide.
- O-1812 wikiPageWikiLink Cannabinoid_receptor.
- O-1812 wikiPageWikiLink Cannabinoid_receptor_1.
- O-1812 wikiPageWikiLink Cannabinoid_receptor_2_(macrophage).
- O-1812 wikiPageWikiLink Cannabinoid_receptor_type_1.
- O-1812 wikiPageWikiLink Cannabinoid_receptor_type_2.
- O-1812 wikiPageWikiLink Category:Cannabinoids.
- O-1812 wikiPageWikiLink Category:Nitriles.
- O-1812 wikiPageWikiLink Dissociation_constant.
- O-1812 wikiPageWikiLink Eicosanoid.
- O-1812 wikiPageWikiLink Methanandamide.
- O-1812 wikiPageWikiLink O-1057.
- O-1812 wikiPageWikiLink O-774.
- O-1812 wikiPageWikiLinkText "O-1812".
- O-1812 c "26".
- O-1812 casNumber "342882".
- O-1812 chemspiderid "7998855".
- O-1812 h "42".
- O-1812 hasPhotoCollection O-1812.
- O-1812 inchi "1".
- O-1812 inchikey "WZQHSBKOWZOASP-QLZKPENWBF".
- O-1812 iupacName "-20".
- O-1812 iupharLigand "732".
- O-1812 molecularWeight "414.622".
- O-1812 n "2".
- O-1812 o "2".
- O-1812 pubchem "9823107".
- O-1812 smiles "C[C@H]NCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC#N".
- O-1812 stdinchi "1".
- O-1812 stdinchikey "WZQHSBKOWZOASP-QLZKPENWSA-N".
- O-1812 verifiedfields "changed".
- O-1812 verifiedrevid "445942332".
- O-1812 watchedfields "changed".
- O-1812 wikiPageUsesTemplate Template:Alkene-stub.
- O-1812 wikiPageUsesTemplate Template:Cannabinoid-stub.
- O-1812 wikiPageUsesTemplate Template:Cannabinoids.
- O-1812 wikiPageUsesTemplate Template:Drugbox.
- O-1812 wikiPageUsesTemplate Template:Reflist.
- O-1812 subject Category:Cannabinoids.
- O-1812 subject Category:Nitriles.
- O-1812 type Article.
- O-1812 type ChemicalSubstance.
- O-1812 type Drug.
- O-1812 type Group.
- O-1812 type Alkene.
- O-1812 type Article.
- O-1812 type Cannabinoid.
- O-1812 type Chemical.
- O-1812 type Drug.
- O-1812 type Group.
- O-1812 type Nitrile.
- O-1812 type ChemicalObject.
- O-1812 type Thing.
- O-1812 type Q8386.
- O-1812 comment "O-1812 is an eicosanoid derivative related to anandamide that acts as a potent and highly selective agonist for the cannabinoid receptor CB1, with a Ki of 3.4nM at CB1 and 3870nM at CB2. Unlike most related compounds, O-1812 is metabolically stable against rapid breakdown by enzymes, and produces a cannabinoid-like discriminative effect in rats, which is similar but not identical to that produced by cannabinoid drugs of other chemical classes.".
- O-1812 label "O-1812".
- O-1812 sameAs m.0gwykg2.
- O-1812 sameAs O-1812.
- O-1812 sameAs O-1812.
- O-1812 sameAs Q7071993.
- O-1812 sameAs Q7071993.
- O-1812 wasDerivedFrom O-1812?oldid=678987597.
- O-1812 depiction O-1812_structure.png.
- O-1812 isPrimaryTopicOf O-1812.