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- Nicastrin abstract "Nicastrin, also known as NCSTN, is a protein that in humans is encoded by the NCSTN gene.Nicastrin (abbreviated NCT) is a protein that is part of the gamma secretase protein complex, which is one of the proteases involved in processing amyloid precursor protein (APP) to the short Alzheimer's disease-associated peptide amyloid beta. The other proteins in the complex are presenilin, which is the catalytically active component of the complex, APH-1 (anterior pharynx-defective 1), and PEN-2 (presenilin enhancer 2). Nicastrin itself is not catalytically active, but instead promotes the maturation and proper trafficking of the other proteins in the complex, all of which undergo significant post-translational modification before becoming active in the cell. Nicastrin has also been identified as a regulator of neprilysin, an enzyme involved in the degradation of amyloid beta fragment.".
- Nicastrin entrezgene "23385".
- Nicastrin wikiPageID "9869709".
- Nicastrin wikiPageLength "14210".
- Nicastrin wikiPageOutDegree "23".
- Nicastrin wikiPageRevisionID "678984736".
- Nicastrin wikiPageWikiLink APH-1.
- Nicastrin wikiPageWikiLink Alzheimers_disease.
- Nicastrin wikiPageWikiLink Amyloid_beta.
- Nicastrin wikiPageWikiLink Amyloid_precursor_protein.
- Nicastrin wikiPageWikiLink Catalysis.
- Nicastrin wikiPageWikiLink Category:Alzheimers_disease.
- Nicastrin wikiPageWikiLink Category:Proteins.
- Nicastrin wikiPageWikiLink Early-onset_Alzheimers_disease.
- Nicastrin wikiPageWikiLink Enzyme.
- Nicastrin wikiPageWikiLink Familial_Alzheimers_Disease.
- Nicastrin wikiPageWikiLink Gamma_secretase.
- Nicastrin wikiPageWikiLink Gene.
- Nicastrin wikiPageWikiLink Multiprotein_complex.
- Nicastrin wikiPageWikiLink Neprilysin.
- Nicastrin wikiPageWikiLink Nicastro.
- Nicastrin wikiPageWikiLink PEN-2.
- Nicastrin wikiPageWikiLink PSEN1.
- Nicastrin wikiPageWikiLink PSEN2.
- Nicastrin wikiPageWikiLink Post-translational_modification.
- Nicastrin wikiPageWikiLink Presenilin.
- Nicastrin wikiPageWikiLink Protease.
- Nicastrin wikiPageWikiLink Protein.
- Nicastrin wikiPageWikiLink Protein-protein_interaction.
- Nicastrin wikiPageWikiLink Protein_complex.
- Nicastrin wikiPageWikiLink Protein–protein_interaction.
- Nicastrin wikiPageWikiLinkText "NCSTN".
- Nicastrin wikiPageWikiLinkText "Nicastrin".
- Nicastrin wikiPageWikiLinkText "nicastrin".
- Nicastrin hasPhotoCollection Nicastrin.
- Nicastrin requireManualInspection "no".
- Nicastrin updateCitations "yes".
- Nicastrin updatePage "yes".
- Nicastrin updateProteinBox "yes".
- Nicastrin updateSummary "yes".
- Nicastrin wikiPageUsesTemplate Template:Gene-1-stub.
- Nicastrin wikiPageUsesTemplate Template:MeshName.
- Nicastrin wikiPageUsesTemplate Template:PBB.
- Nicastrin wikiPageUsesTemplate Template:PBB_Controls.
- Nicastrin wikiPageUsesTemplate Template:PBB_Further_reading.
- Nicastrin wikiPageUsesTemplate Template:Refbegin.
- Nicastrin wikiPageUsesTemplate Template:Refend.
- Nicastrin wikiPageUsesTemplate Template:Reflist.
- Nicastrin subject Category:Alzheimers_disease.
- Nicastrin subject Category:Proteins.
- Nicastrin hypernym Protein.
- Nicastrin type Biomolecule.
- Nicastrin type Protein.
- Nicastrin type Biomolecule.
- Nicastrin type Disorder.
- Nicastrin type Nutrient.
- Nicastrin type Thing.
- Nicastrin type Q206229.
- Nicastrin type Q8054.
- Nicastrin comment "Nicastrin, also known as NCSTN, is a protein that in humans is encoded by the NCSTN gene.Nicastrin (abbreviated NCT) is a protein that is part of the gamma secretase protein complex, which is one of the proteases involved in processing amyloid precursor protein (APP) to the short Alzheimer's disease-associated peptide amyloid beta.".
- Nicastrin label "Nicastrin".
- Nicastrin sameAs Nicastrina.
- Nicastrin sameAs m.02pvdcy.
- Nicastrin sameAs Q7024546.
- Nicastrin sameAs Q7024546.
- Nicastrin wasDerivedFrom Nicastrin?oldid=678984736.
- Nicastrin isPrimaryTopicOf Nicastrin.