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- Neuropeptide_S_receptor abstract "The neuropeptide S receptor (NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S (NPS). It was formerly an orphan receptor, GPR154, until the discovery of neuropeptide S as the endogenous ligand.In the CNS, activation of the NPSR by NPS promotes arousal and anxiolytic-like effects.In addition, mututations in NPSR have been linked to a susceptibility to asthma. Hence NPSR has also been called GPRA (G protein-coupled receptor for asthma susceptibility). Activation of NPSR in the airway epithelium has a number of effects including upregulation of matrix metalloproteinases which are involved in the pathogenesis of asthma.This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.".
- Neuropeptide_S_receptor entrezgene "387129".
- Neuropeptide_S_receptor wikiPageExternalLink ChapterMenuForward?chapterID=1324.
- Neuropeptide_S_receptor wikiPageID "14051706".
- Neuropeptide_S_receptor wikiPageLength "10714".
- Neuropeptide_S_receptor wikiPageOutDegree "12".
- Neuropeptide_S_receptor wikiPageRevisionID "678983661".
- Neuropeptide_S_receptor wikiPageWikiLink Anxiolytic.
- Neuropeptide_S_receptor wikiPageWikiLink Arousal.
- Neuropeptide_S_receptor wikiPageWikiLink Asthma.
- Neuropeptide_S_receptor wikiPageWikiLink Category:G_protein_coupled_receptors.
- Neuropeptide_S_receptor wikiPageWikiLink Central_nervous_system.
- Neuropeptide_S_receptor wikiPageWikiLink Epithelium.
- Neuropeptide_S_receptor wikiPageWikiLink G-protein_coupled_receptor.
- Neuropeptide_S_receptor wikiPageWikiLink G_protein–coupled_receptor.
- Neuropeptide_S_receptor wikiPageWikiLink Integral_membrane_protein.
- Neuropeptide_S_receptor wikiPageWikiLink Matrix_metalloproteinase.
- Neuropeptide_S_receptor wikiPageWikiLink Neuropeptide_S.
- Neuropeptide_S_receptor wikiPageWikiLink Orphan_receptor.
- Neuropeptide_S_receptor wikiPageWikiLink Pathogenesis.
- Neuropeptide_S_receptor wikiPageWikiLinkText "NPSR".
- Neuropeptide_S_receptor wikiPageWikiLinkText "NPSR1".
- Neuropeptide_S_receptor wikiPageWikiLinkText "Neuropeptide S receptor".
- Neuropeptide_S_receptor hasPhotoCollection Neuropeptide_S_receptor.
- Neuropeptide_S_receptor requireManualInspection "no".
- Neuropeptide_S_receptor summaryText "This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.".
- Neuropeptide_S_receptor updateCitations "yes".
- Neuropeptide_S_receptor updatePage "yes".
- Neuropeptide_S_receptor updateProteinBox "yes".
- Neuropeptide_S_receptor updateSummary "yes".
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Cite_web.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:G_protein-coupled_receptors.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:MeshName.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:NLM_content.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Neuropeptide_receptors.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Neuropeptidergics.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:PBB.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:PBB_Controls.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:PBB_Further_reading.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:PBB_Summary.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Refbegin.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Refend.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Reflist.
- Neuropeptide_S_receptor wikiPageUsesTemplate Template:Transmembranereceptor-stub.
- Neuropeptide_S_receptor subject Category:G_protein_coupled_receptors.
- Neuropeptide_S_receptor hypernym Member.
- Neuropeptide_S_receptor type Article.
- Neuropeptide_S_receptor type Biomolecule.
- Neuropeptide_S_receptor type Person.
- Neuropeptide_S_receptor type Protein.
- Neuropeptide_S_receptor type Article.
- Neuropeptide_S_receptor type Institute.
- Neuropeptide_S_receptor type Source.
- Neuropeptide_S_receptor type Thing.
- Neuropeptide_S_receptor type Q206229.
- Neuropeptide_S_receptor type Q8054.
- Neuropeptide_S_receptor comment "The neuropeptide S receptor (NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S (NPS). It was formerly an orphan receptor, GPR154, until the discovery of neuropeptide S as the endogenous ligand.In the CNS, activation of the NPSR by NPS promotes arousal and anxiolytic-like effects.In addition, mututations in NPSR have been linked to a susceptibility to asthma.".
- Neuropeptide_S_receptor label "Neuropeptide S receptor".
- Neuropeptide_S_receptor sameAs m.03cs4h1.
- Neuropeptide_S_receptor sameAs Neuropeptidni_S_receptor.
- Neuropeptide_S_receptor sameAs Neuropeptidni_S_receptor.
- Neuropeptide_S_receptor sameAs Q7002518.
- Neuropeptide_S_receptor sameAs Q7002518.
- Neuropeptide_S_receptor wasDerivedFrom Neuropeptide_S_receptor?oldid=678983661.
- Neuropeptide_S_receptor isPrimaryTopicOf Neuropeptide_S_receptor.