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- Morphine-3-glucuronide abstract "Morphine-3-glucuronide is a metabolite of morphine produced by UGT2B7. It is not active as an opioid agonist, but does have some action as a convulsant, which does not appear to be mediated through opioid receptors, but rather through interaction with glycine and/or GABA receptors. As a polar compound, it has a limited ability to cross the blood–brain barrier, but renal failure may lead to its accumulation and result in seizures. Probenecid and inhibitors of P-glycoprotein can enhance uptake of morphine-3-glucuronide and, to a lesser extent, morphine-6-glucuronide. Reported side effects related to the accumulation of this metabolite include convulsions, agitation, hallucinations, hyperalgesia, and coma.".
- Morphine-3-glucuronide thumbnail Morphine-3-glucuronide.svg?width=300.
- Morphine-3-glucuronide wikiPageID "10751306".
- Morphine-3-glucuronide wikiPageLength "3960".
- Morphine-3-glucuronide wikiPageOutDegree "29".
- Morphine-3-glucuronide wikiPageRevisionID "670392752".
- Morphine-3-glucuronide wikiPageWikiLink 3-Monoacetylmorphine.
- Morphine-3-glucuronide wikiPageWikiLink Agonist.
- Morphine-3-glucuronide wikiPageWikiLink Blood–brain_barrier.
- Morphine-3-glucuronide wikiPageWikiLink Buprenorphine-3-glucuronide.
- Morphine-3-glucuronide wikiPageWikiLink Category:Alcohols.
- Morphine-3-glucuronide wikiPageWikiLink Category:Convulsants.
- Morphine-3-glucuronide wikiPageWikiLink Category:GABAA_receptor_negative_allosteric_modulators.
- Morphine-3-glucuronide wikiPageWikiLink Category:Glucuronides.
- Morphine-3-glucuronide wikiPageWikiLink Category:Glycine_receptor_antagonists.
- Morphine-3-glucuronide wikiPageWikiLink Category:Morphinans.
- Morphine-3-glucuronide wikiPageWikiLink Category:Opioid_metabolites.
- Morphine-3-glucuronide wikiPageWikiLink Coma.
- Morphine-3-glucuronide wikiPageWikiLink Convulsant.
- Morphine-3-glucuronide wikiPageWikiLink Epileptic_seizure.
- Morphine-3-glucuronide wikiPageWikiLink GABA_receptor.
- Morphine-3-glucuronide wikiPageWikiLink Glycine_receptor.
- Morphine-3-glucuronide wikiPageWikiLink Hallucination.
- Morphine-3-glucuronide wikiPageWikiLink Hyperalgesia.
- Morphine-3-glucuronide wikiPageWikiLink Metabolite.
- Morphine-3-glucuronide wikiPageWikiLink Morphine.
- Morphine-3-glucuronide wikiPageWikiLink Morphine-6-glucuronide.
- Morphine-3-glucuronide wikiPageWikiLink Morphine-N-oxide.
- Morphine-3-glucuronide wikiPageWikiLink Opioid_receptor.
- Morphine-3-glucuronide wikiPageWikiLink P-glycoprotein.
- Morphine-3-glucuronide wikiPageWikiLink Probenecid.
- Morphine-3-glucuronide wikiPageWikiLink Psychomotor_agitation.
- Morphine-3-glucuronide wikiPageWikiLink Seizure.
- Morphine-3-glucuronide wikiPageWikiLink UGT2B7.
- Morphine-3-glucuronide wikiPageWikiLinkText "M3G".
- Morphine-3-glucuronide wikiPageWikiLinkText "Morphine-3-glucuronide".
- Morphine-3-glucuronide wikiPageWikiLinkText "morphine-3-glucuronide".
- Morphine-3-glucuronide hasPhotoCollection Morphine-3-glucuronide.
- Morphine-3-glucuronide imagefile "Morphine-3-glucuronide.svg".
- Morphine-3-glucuronide imagesize "250".
- Morphine-3-glucuronide verifiedfields "changed".
- Morphine-3-glucuronide verifiedrevid "462255487".
- Morphine-3-glucuronide wikiPageUsesTemplate Template:Chembox.
- Morphine-3-glucuronide wikiPageUsesTemplate Template:Citation_needed.
- Morphine-3-glucuronide wikiPageUsesTemplate Template:GABAergics.
- Morphine-3-glucuronide wikiPageUsesTemplate Template:Glycinergics.
- Morphine-3-glucuronide wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Morphine-3-glucuronide wikiPageUsesTemplate Template:Reflist.
- Morphine-3-glucuronide subject Category:Alcohols.
- Morphine-3-glucuronide subject Category:Convulsants.
- Morphine-3-glucuronide subject Category:GABAA_receptor_negative_allosteric_modulators.
- Morphine-3-glucuronide subject Category:Glucuronides.
- Morphine-3-glucuronide subject Category:Glycine_receptor_antagonists.
- Morphine-3-glucuronide subject Category:Morphinans.
- Morphine-3-glucuronide subject Category:Opioid_metabolites.
- Morphine-3-glucuronide hypernym Metabolite.
- Morphine-3-glucuronide type ChemicalCompound.
- Morphine-3-glucuronide type ChemicalSubstance.
- Morphine-3-glucuronide type Alcohol.
- Morphine-3-glucuronide type Chemical.
- Morphine-3-glucuronide type Glycoside.
- Morphine-3-glucuronide type Heterocycle.
- Morphine-3-glucuronide type Opioid.
- Morphine-3-glucuronide type ChemicalObject.
- Morphine-3-glucuronide type Thing.
- Morphine-3-glucuronide type Q11173.
- Morphine-3-glucuronide comment "Morphine-3-glucuronide is a metabolite of morphine produced by UGT2B7. It is not active as an opioid agonist, but does have some action as a convulsant, which does not appear to be mediated through opioid receptors, but rather through interaction with glycine and/or GABA receptors. As a polar compound, it has a limited ability to cross the blood–brain barrier, but renal failure may lead to its accumulation and result in seizures.".
- Morphine-3-glucuronide label "Morphine-3-glucuronide".
- Morphine-3-glucuronide sameAs مورفین-۳-گلوکورونید.
- Morphine-3-glucuronide sameAs m.02qp0t6.
- Morphine-3-glucuronide sameAs Морфин-3-глюкуронид.
- Morphine-3-glucuronide sameAs Morfin-3-glukuronid.
- Morphine-3-glucuronide sameAs Morfin-3-glukuronid.
- Morphine-3-glucuronide sameAs Q4303467.
- Morphine-3-glucuronide sameAs Q4303467.
- Morphine-3-glucuronide wasDerivedFrom Morphine-3-glucuronide?oldid=670392752.
- Morphine-3-glucuronide depiction Morphine-3-glucuronide.svg.
- Morphine-3-glucuronide isPrimaryTopicOf Morphine-3-glucuronide.