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Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Methylnaltrexone> ?p ?o }

• Methylnaltrexone abstract "Methylnaltrexone (MNTX, trade name Relistor) is one of the newer agents of peripherally-acting μ-opioid antagonists that act to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals. Because MNTX is a quaternary ammonium cation, it cannot cross the blood–brain barrier, and so has antagonist effects throughout the body, counteracting effects such as itching and constipation, but without affecting opioid effects in the brain such as analgesia. However, since a significant fraction (up to 60%) of opioid analgesia can be mediated by opioid receptors on peripheral sensory neurons, particularly in inflammatory conditions such as arthritis, traumatic or surgical pain, MNTX may increase pain under such circumstances.".
• Methylnaltrexone atcPrefix "A06".
• Methylnaltrexone atcSuffix "AH01".
• Methylnaltrexone casNumber "83387-25-1".
• Methylnaltrexone drugbank "DB06800".
• Methylnaltrexone fdaUniiCode "0RK7M7IABE".
• Methylnaltrexone iupacName "(5α)-17-(cyclopropylmethyl)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinanium-17-ium-6-one".
• Methylnaltrexone pubchem "5361918".
• Methylnaltrexone thumbnail Methylnaltrexone.svg?width=300.
• Methylnaltrexone wikiPageID "11463287".
• Methylnaltrexone wikiPageLength "13763".
• Methylnaltrexone wikiPageOutDegree "26".
• Methylnaltrexone wikiPageRevisionID "679931936".
• Methylnaltrexone wikiPageWikiLink (+)-Naloxone.
• Methylnaltrexone wikiPageWikiLink Analgesia.
• Methylnaltrexone wikiPageWikiLink Analgesic.
• Methylnaltrexone wikiPageWikiLink Blood–brain_barrier.
• Methylnaltrexone wikiPageWikiLink Category:Alcohols.
• Methylnaltrexone wikiPageWikiLink Category:Cyclopropanes.
• Methylnaltrexone wikiPageWikiLink Category:Kappa_antagonists.
• Methylnaltrexone wikiPageWikiLink Category:Ketones.
• Methylnaltrexone wikiPageWikiLink Category:Morphinans.
• Methylnaltrexone wikiPageWikiLink Category:Opioid_antagonists.
• Methylnaltrexone wikiPageWikiLink Category:Phenols.
• Methylnaltrexone wikiPageWikiLink Category:Quaternary_ammonium_compounds.
• Methylnaltrexone wikiPageWikiLink Category:Semisynthetic_opioids.
• Methylnaltrexone wikiPageWikiLink Constipation.
• Methylnaltrexone wikiPageWikiLink Drug_withdrawal.
• Methylnaltrexone wikiPageWikiLink Ileus.
• Methylnaltrexone wikiPageWikiLink Itch.
• Methylnaltrexone wikiPageWikiLink Itching.
• Methylnaltrexone wikiPageWikiLink Laxative.
• Methylnaltrexone wikiPageWikiLink Laxatives.
• Methylnaltrexone wikiPageWikiLink Loperamide.
• Methylnaltrexone wikiPageWikiLink Mu_opioid_receptor.
• Methylnaltrexone wikiPageWikiLink Naltrexone.
• Methylnaltrexone wikiPageWikiLink Opioid.
• Methylnaltrexone wikiPageWikiLink Opioid-induced_constipation.
• Methylnaltrexone wikiPageWikiLink Quaternary_ammonium_cation.
• Methylnaltrexone wikiPageWikiLink Receptor_antagonist.
• Methylnaltrexone wikiPageWikiLink Wyeth.
• Methylnaltrexone wikiPageWikiLink Μ-opioid_receptor.
• Methylnaltrexone wikiPageWikiLinkText "Alcohol-wipes".
• Methylnaltrexone wikiPageWikiLinkText "MNTX".
• Methylnaltrexone wikiPageWikiLinkText "Methylnaltrexone".
• Methylnaltrexone wikiPageWikiLinkText "methylnaltrexone".
• Methylnaltrexone atcPrefix "A06".
• Methylnaltrexone atcSuffix "AH01".
• Methylnaltrexone c "21".
• Methylnaltrexone casNumber "83387".
• Methylnaltrexone chembl "1186579".
• Methylnaltrexone chemspiderid "4514884".
• Methylnaltrexone drugbank "DB06800".
• Methylnaltrexone eliminationHalfLife "28800.0".
• Methylnaltrexone excretion "Urine , faeces".
• Methylnaltrexone h "26".
• Methylnaltrexone hasPhotoCollection Methylnaltrexone.
• Methylnaltrexone inchi "1".
• Methylnaltrexone inchikey "JVLBPIPGETUEET-LZECNIFCBY".
• Methylnaltrexone iupacName "-17".
• Methylnaltrexone iupharLigand "7563".
• Methylnaltrexone legalAu "S4".
• Methylnaltrexone legalCa "Schedule VI".
• Methylnaltrexone legalUk "POM".
• Methylnaltrexone legalUs "Rx-only".
• Methylnaltrexone licenceEu "Relistor".
• Methylnaltrexone licenceUs "Methylnaltrexone".
• Methylnaltrexone medlineplus "a608052".
• Methylnaltrexone metabolism "Hepatic".
• Methylnaltrexone molecularWeight "356.44".
• Methylnaltrexone n "1".
• Methylnaltrexone o "4".
• Methylnaltrexone pregnancyAu "B1".
• Methylnaltrexone pregnancyUs "B".
• Methylnaltrexone proteinBound "11".
• Methylnaltrexone pubchem "5361918".
• Methylnaltrexone routesOfAdministration "Oral, intravenous, subcutaneous".
• Methylnaltrexone smiles "O=C6[C@@H]3Oc1c2cC[C@@H]4[C@@]CC6".
• Methylnaltrexone stdinchi "1".
• Methylnaltrexone stdinchikey "JVLBPIPGETUEET-GAAHOAFPSA-O".
• Methylnaltrexone synonyms "MNTX, naltrexone-methyl-bromide".
• Methylnaltrexone tradename "Relistor".
• Methylnaltrexone unii "0".
• Methylnaltrexone verifiedfields "changed".
• Methylnaltrexone verifiedrevid "459588162".
• Methylnaltrexone width "200".
• Methylnaltrexone wikiPageUsesTemplate Template:Citation_needed.
• Methylnaltrexone wikiPageUsesTemplate Template:Cite_journal.
• Methylnaltrexone wikiPageUsesTemplate Template:Convert.
• Methylnaltrexone wikiPageUsesTemplate Template:Drugbox.
• Methylnaltrexone wikiPageUsesTemplate Template:Laxatives.
• Methylnaltrexone wikiPageUsesTemplate Template:Opioidergics.
• Methylnaltrexone wikiPageUsesTemplate Template:Refimprove_section.
• Methylnaltrexone wikiPageUsesTemplate Template:Reflist.
• Methylnaltrexone subject Category:Alcohols.
• Methylnaltrexone subject Category:Cyclopropanes.
• Methylnaltrexone subject Category:Kappa_antagonists.
• Methylnaltrexone subject Category:Ketones.
• Methylnaltrexone subject Category:Morphinans.
• Methylnaltrexone subject Category:Opioid_antagonists.

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