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- Methylisopropyllysergamide abstract "Methylisopropyllysergamide (lysergic acid methylisopropyl amide, MIPLA) is an analogue of LSD that was originally discovered by Albert Hofmann at Sandoz during the original structure-activity research into LSD. It has subsequently been investigated in more detail by the team led by David E. Nichols at Purdue University. Methylisopropyllysergamide is a structural isomer of LSD, with the alkyl groups on the amide nitrogen having been subjected to a methylene shuffle. MIPLA and its ethylisopropyl homologue are the only simple N,N-dialkyl lysergamides that approach the potency of LSD itself, being around 1/3-1/2 the potency of LSD, while all other dialkyl analogues tested (dimethyl, dipropyl, methylethyl etc.) are only around 1/10 as potent as LSD, although some N-monoalkyl lysergamides such as the sec-butyl and t-butyl derivatives were also found to show an activity profile and potency comparable to LSD, and the mono-isopropyl derivative is only slightly weaker than MIPLA. Apart from its lower potency, the hallucinogenic effects of methylisopropyllysergamide are similar to those of LSD itself, and the main use for this drug has been in studies of the binding site at the 5-HT2A receptor through which LSD exerts most of its pharmacological effects.".
- Methylisopropyllysergamide atcPrefix "none".
- Methylisopropyllysergamide iupacName "(8β)-N-Isopropyl-N,6-dimethyl-9,10-didehydroergoline-8-carboxamide".
- Methylisopropyllysergamide thumbnail MIPLSD.svg?width=300.
- Methylisopropyllysergamide wikiPageID "19913392".
- Methylisopropyllysergamide wikiPageLength "3183".
- Methylisopropyllysergamide wikiPageOutDegree "14".
- Methylisopropyllysergamide wikiPageRevisionID "607021597".
- Methylisopropyllysergamide wikiPageWikiLink 5-HT2A_receptor.
- Methylisopropyllysergamide wikiPageWikiLink Albert_Hofmann.
- Methylisopropyllysergamide wikiPageWikiLink Category:Lysergamides.
- Methylisopropyllysergamide wikiPageWikiLink Category:Psychedelic_drugs.
- Methylisopropyllysergamide wikiPageWikiLink David_E._Nichols.
- Methylisopropyllysergamide wikiPageWikiLink LSD.
- Methylisopropyllysergamide wikiPageWikiLink Lysergic_acid_2-butyl_amide.
- Methylisopropyllysergamide wikiPageWikiLink Lysergic_acid_3-pentyl_amide.
- Methylisopropyllysergamide wikiPageWikiLink Lysergic_acid_diethylamide.
- Methylisopropyllysergamide wikiPageWikiLink Methylene_shuffle.
- Methylisopropyllysergamide wikiPageWikiLink Novartis.
- Methylisopropyllysergamide wikiPageWikiLink Purdue_University.
- Methylisopropyllysergamide wikiPageWikiLink Receptor_(biochemistry).
- Methylisopropyllysergamide wikiPageWikiLink Sandoz.
- Methylisopropyllysergamide wikiPageWikiLink Structural_isomer.
- Methylisopropyllysergamide wikiPageWikiLinkText "MIPLA".
- Methylisopropyllysergamide wikiPageWikiLinkText "Methylisopropyllysergamide".
- Methylisopropyllysergamide atcPrefix "none".
- Methylisopropyllysergamide c "20".
- Methylisopropyllysergamide h "25".
- Methylisopropyllysergamide hasPhotoCollection Methylisopropyllysergamide.
- Methylisopropyllysergamide iupacName "-N-Isopropyl-N,6-dimethyl-9,10-didehydroergoline-8-carboxamide".
- Methylisopropyllysergamide molecularWeight "323.431".
- Methylisopropyllysergamide n "3".
- Methylisopropyllysergamide o "1".
- Methylisopropyllysergamide smiles "C4NC1Cc2cncc2c3C1=CC4CNCC".
- Methylisopropyllysergamide synonyms "- N-methyl- N-isopropyl- 7-methyl- 4,6,6a,7,8,9- hexahydroindolo- [4,3-fg] quinoline- 9- carboxamide;".
- Methylisopropyllysergamide verifiedrevid "452010274".
- Methylisopropyllysergamide watchedfields "changed".
- Methylisopropyllysergamide width "140".
- Methylisopropyllysergamide wikiPageUsesTemplate Template:Drugbox.
- Methylisopropyllysergamide wikiPageUsesTemplate Template:Hallucinogen-stub.
- Methylisopropyllysergamide wikiPageUsesTemplate Template:Hallucinogenic_lysergamides.
- Methylisopropyllysergamide wikiPageUsesTemplate Template:Reflist.
- Methylisopropyllysergamide subject Category:Lysergamides.
- Methylisopropyllysergamide subject Category:Psychedelic_drugs.
- Methylisopropyllysergamide hypernym Analogue.
- Methylisopropyllysergamide type Article.
- Methylisopropyllysergamide type ChemicalSubstance.
- Methylisopropyllysergamide type Drug.
- Methylisopropyllysergamide type Amide.
- Methylisopropyllysergamide type Article.
- Methylisopropyllysergamide type Chemical.
- Methylisopropyllysergamide type Dissociative.
- Methylisopropyllysergamide type Drug.
- Methylisopropyllysergamide type Lysergamide.
- Methylisopropyllysergamide type ChemicalObject.
- Methylisopropyllysergamide type Thing.
- Methylisopropyllysergamide type Q8386.
- Methylisopropyllysergamide comment "Methylisopropyllysergamide (lysergic acid methylisopropyl amide, MIPLA) is an analogue of LSD that was originally discovered by Albert Hofmann at Sandoz during the original structure-activity research into LSD. It has subsequently been investigated in more detail by the team led by David E. Nichols at Purdue University. Methylisopropyllysergamide is a structural isomer of LSD, with the alkyl groups on the amide nitrogen having been subjected to a methylene shuffle.".
- Methylisopropyllysergamide label "Methylisopropyllysergamide".
- Methylisopropyllysergamide sameAs m.04q1xsp.
- Methylisopropyllysergamide sameAs Metilizopropilisergamid.
- Methylisopropyllysergamide sameAs Metilizopropilisergamid.
- Methylisopropyllysergamide sameAs Q15409386.
- Methylisopropyllysergamide sameAs Q15409386.
- Methylisopropyllysergamide wasDerivedFrom Methylisopropyllysergamide?oldid=607021597.
- Methylisopropyllysergamide depiction MIPLSD.svg.
- Methylisopropyllysergamide isPrimaryTopicOf Methylisopropyllysergamide.