Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Methamphetamine> ?p ?o }
- Methamphetamine abstract "Methamphetamine (contracted from N-methyl-alpha-methylphenethylamine) is a strong central nervous system (CNS) stimulant that is mainly used as a recreational drug. Methamphetamine hydrochloride is approved by the United States Food and Drug Administration (USFDA) under the trade name Desoxyn for attention deficit hyperactivity disorder and obesity in adults and children, and is sometimes prescribed off label for narcolepsy and idiopathic hypersomnia. It is rarely prescribed due to concerns involving human neurotoxicity, the availability of safer substitute drugs with comparable treatment efficacy, and the high potential for recreational use, among other concerns. Methamphetamine exists as two dextrorotary and levorotary enantiomers: dextromethamphetamine and levomethamphetamine. Methamphetamine properly refers to a specific chemical, the racemic free base, which is an equal parts mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms. Dextromethamphetamine is a stronger CNS stimulant than levomethamphetamine; however, both enantiomers are neurotoxic and addictive.Both methamphetamine and enantiopure dextromethamphetamine are illicitly trafficked and sold due to their potential for recreational use as an aphrodisiac and euphoriant; the highest prevalence of illegal methamphetamine use occurs in parts of Asia, Oceania, and in the United States, where both racemic methamphetamine, levomethamphetamine, and dextromethamphetamine are classified as schedule II controlled substances; however, enantiopure levomethamphetamine is available as an over-the-counter drug for use as an inhaled nasal decongestant in the United States. Internationally, the production, distribution, sale, and possession of methamphetamine is restricted or banned in many other countries due to its placement in schedule II of the United Nations Convention on Psychotropic Substances treaty. While enantiopure dextromethamphetamine is a more potent drug than racemic methamphetamine, the racemic form is sometimes produced and sold instead of dextromethamphetamine due to the relative ease of its synthesis by certain methods and the limited availability of associated chemical precursors.In low doses, methamphetamine can elevate mood, increase alertness, concentration, and energy in fatigued individuals, reduce appetite and promote (initial) weight loss. At higher doses, it can induce psychosis, rhabdomyolysis and cerebral hemorrhage. Chronic high dose use can precipitate unpredictable and rapid mood swings, prominent delusions and violent behavior. Recreationally, methamphetamine's ability to increase energy has been reported to lift mood and increase sexual desire to an extent of users ability to engage in sexual activity continuously for several days. Methamphetamine is known to have a high addiction liability (i.e., compulsive methamphetamine use) and dependence liability (i.e., withdrawal symptoms occur when methamphetamine use ceases). Heavy recreational use of methamphetamine may lead to a post-acute-withdrawal syndrome, which can persist for months beyond the typical withdrawal period.[i] Unlike amphetamine, methamphetamine is neurotoxic to humans, damaging both dopamine and serotonin neurons in the CNS.[i] Contrary to the long-term use of amphetamine,[iii] there is evidence that methamphetamine causes brain damage from long-term use in humans;[ii] this damage includes adverse changes in brain structure and function, such as reductions in grey matter volume in several brain regions and adverse changes in markers of metabolic integrity.[ii]Methamphetamine belongs to the substituted phenethylamine and substituted amphetamine chemical classes. It is related to the other dimethylphenethylamines as a positional isomer of these compounds, which share the common chemical formula: C10H15N1.".
- Methamphetamine thumbnail N-Methylamphetamin.svg?width=300.
- Methamphetamine wikiPageExternalLink r?dbs+hsdb:@term+@rn+@rel+537-46-2.
- Methamphetamine wikiPageExternalLink pim334.htm.
- Methamphetamine wikiPageID "11038318".
- Methamphetamine wikiPageLength "101412".
- Methamphetamine wikiPageOutDegree "460".
- Methamphetamine wikiPageRevisionID "683226986".
- Methamphetamine wikiPageWikiLink 4-Hydroxyamphetamine.
- Methamphetamine wikiPageWikiLink 4-Hydroxyphenylacetone.
- Methamphetamine wikiPageWikiLink 4-hydroxyamphetamine.
- Methamphetamine wikiPageWikiLink 4-hydroxynorephedrine.
- Methamphetamine wikiPageWikiLink 4-hydroxyphenylacetone.
- Methamphetamine wikiPageWikiLink Acne.
- Methamphetamine wikiPageWikiLink Acne_vulgaris.
- Methamphetamine wikiPageWikiLink Activated_carbon.
- Methamphetamine wikiPageWikiLink Activated_charcoal.
- Methamphetamine wikiPageWikiLink Addiction.
- Methamphetamine wikiPageWikiLink Addictive.
- Methamphetamine wikiPageWikiLink Adenylate_cyclase.
- Methamphetamine wikiPageWikiLink Adenylyl_cyclase.
- Methamphetamine wikiPageWikiLink Adrenergic_storm.
- Methamphetamine wikiPageWikiLink Aggression.
- Methamphetamine wikiPageWikiLink Agonist.
- Methamphetamine wikiPageWikiLink Akira_Ogata.
- Methamphetamine wikiPageWikiLink Alcoholism.
- Methamphetamine wikiPageWikiLink Alertness.
- Methamphetamine wikiPageWikiLink Alpha-2_adrenergic_receptor.
- Methamphetamine wikiPageWikiLink American_Dental_Association.
- Methamphetamine wikiPageWikiLink Amide.
- Methamphetamine wikiPageWikiLink Amphetamine.
- Methamphetamine wikiPageWikiLink Anhedonia.
- Methamphetamine wikiPageWikiLink Anorexia_(symptom).
- Methamphetamine wikiPageWikiLink Antidepressant.
- Methamphetamine wikiPageWikiLink Antihypertensive_drug.
- Methamphetamine wikiPageWikiLink Antihypertensives.
- Methamphetamine wikiPageWikiLink Antipsychotic.
- Methamphetamine wikiPageWikiLink Anuria.
- Methamphetamine wikiPageWikiLink Anxiety.
- Methamphetamine wikiPageWikiLink Aphrodisiac.
- Methamphetamine wikiPageWikiLink Arrhythmias.
- Methamphetamine wikiPageWikiLink Arteriosclerosis.
- Methamphetamine wikiPageWikiLink Astrocyte.
- Methamphetamine wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- Methamphetamine wikiPageWikiLink Autoxidation.
- Methamphetamine wikiPageWikiLink Behavioral_addiction.
- Methamphetamine wikiPageWikiLink Benzodiazepine.
- Methamphetamine wikiPageWikiLink Benzoic_acid.
- Methamphetamine wikiPageWikiLink Beta_blocker.
- Methamphetamine wikiPageWikiLink Binding_affinity.
- Methamphetamine wikiPageWikiLink Biological_half-life.
- Methamphetamine wikiPageWikiLink Biological_target.
- Methamphetamine wikiPageWikiLink Biomarker.
- Methamphetamine wikiPageWikiLink Biomolecular_target.
- Methamphetamine wikiPageWikiLink Bipolar_disorder.
- Methamphetamine wikiPageWikiLink Blood_pressure.
- Methamphetamine wikiPageWikiLink Bloodstream.
- Methamphetamine wikiPageWikiLink Blood–brain_barrier.
- Methamphetamine wikiPageWikiLink Blurred_vision.
- Methamphetamine wikiPageWikiLink Boxed_warning.
- Methamphetamine wikiPageWikiLink Bradycardia.
- Methamphetamine wikiPageWikiLink Brain_damage.
- Methamphetamine wikiPageWikiLink Breaking_Bad.
- Methamphetamine wikiPageWikiLink Breast_milk.
- Methamphetamine wikiPageWikiLink Bruxism.
- Methamphetamine wikiPageWikiLink Butyrate-CoA_ligase.
- Methamphetamine wikiPageWikiLink Butyrate—CoA_ligase.
- Methamphetamine wikiPageWikiLink CAMP_response_element_binding_protein.
- Methamphetamine wikiPageWikiLink CREB.
- Methamphetamine wikiPageWikiLink CYP2D6.
- Methamphetamine wikiPageWikiLink Calcium_channel.
- Methamphetamine wikiPageWikiLink Cannabinoid.
- Methamphetamine wikiPageWikiLink Cardiac_arrhythmia.
- Methamphetamine wikiPageWikiLink Cardiac_dysrhythmia.
- Methamphetamine wikiPageWikiLink Cardiogenic_shock.
- Methamphetamine wikiPageWikiLink Cardiovascular_disease.
- Methamphetamine wikiPageWikiLink Carnitine.
- Methamphetamine wikiPageWikiLink Catecholamine.
- Methamphetamine wikiPageWikiLink Category:Anorectics.
- Methamphetamine wikiPageWikiLink Category:Cardiac_stimulants.
- Methamphetamine wikiPageWikiLink Category:Euphoriants.
- Methamphetamine wikiPageWikiLink Category:Japanese_inventions.
- Methamphetamine wikiPageWikiLink Category:Management_of_obesity.
- Methamphetamine wikiPageWikiLink Category:Methamphetamine.
- Methamphetamine wikiPageWikiLink Category:Norepinephrine-dopamine_releasing_agents.
- Methamphetamine wikiPageWikiLink Category:Phenethylamines.
- Methamphetamine wikiPageWikiLink Category:Sigma_agonists.
- Methamphetamine wikiPageWikiLink Category:Stimulants.
- Methamphetamine wikiPageWikiLink Category:Sympathomimetics.
- Methamphetamine wikiPageWikiLink Category:TAAR1_agonists.
- Methamphetamine wikiPageWikiLink Category:Treatment_and_management_of_attention_deficit_hyperactivity_disorder.
- Methamphetamine wikiPageWikiLink Category:VMAT_inhibitors.
- Methamphetamine wikiPageWikiLink Caudate_nucleus.
- Methamphetamine wikiPageWikiLink Central_nervous_system.
- Methamphetamine wikiPageWikiLink Cerebral_hemorrhage.
- Methamphetamine wikiPageWikiLink Chemical_classification.
- Methamphetamine wikiPageWikiLink Chemical_formula.
- Methamphetamine wikiPageWikiLink Chemical_synapse.
- Methamphetamine wikiPageWikiLink Chemist.
- Methamphetamine wikiPageWikiLink Chirality_(chemistry).