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- Metaplasticity abstract "Metaplasticity is a term originally coined by W.C. Abraham and M.F. Bear to refer to the plasticity of synaptic plasticity. Until that time synaptic plasticity had referred to the plastic nature of individual synapses. However this new form referred to the plasticity of the plasticity itself, thus the term meta-plasticity. The idea is that the synapse's previous history of activity determines its current plasticity. This may play a role in some of the underlying mechanisms thought to be important in memory and learning such as Long-term potentiation (LTP), Long-term Depression (LTD) and so forth. These mechanisms depend on current synaptic "state", as set by ongoing extrinsic influences such as the level of synaptic inhibition, the activity of modulatory afferents such as catecholamines, and the pool of hormones affecting the synapses under study. Recently, it has become clear that the prior history of synaptic activity is an additional variable that influences the synaptic state, and thereby the degree, of LTP or LTD produced by a given experimental protocol. In a sense, then, synaptic plasticity is governed by an activity-dependent plasticity of the synaptic state; such plasticity of synaptic plasticity has been termed metaplasticity. There is little known about metaplasticity, and there is much research currently underway on the subject, despite its difficulty of study, because of its theoretical importance in brain and cognitive science. Most research of this type is done via cultured hippocampus cells or hippocampal slices.".
- Metaplasticity wikiPageID "5064345".
- Metaplasticity wikiPageLength "17286".
- Metaplasticity wikiPageOutDegree "38".
- Metaplasticity wikiPageRevisionID "678963298".
- Metaplasticity wikiPageWikiLink AMPA.
- Metaplasticity wikiPageWikiLink AMPA_receptor.
- Metaplasticity wikiPageWikiLink Brain.
- Metaplasticity wikiPageWikiLink Cannabinoid_receptor_type_1.
- Metaplasticity wikiPageWikiLink Catecholamine.
- Metaplasticity wikiPageWikiLink Category:Neurophysiology.
- Metaplasticity wikiPageWikiLink Category:Neuroscience.
- Metaplasticity wikiPageWikiLink Cell_culture.
- Metaplasticity wikiPageWikiLink Coincidence_detection_in_neurobiology.
- Metaplasticity wikiPageWikiLink Donald_Hebb.
- Metaplasticity wikiPageWikiLink Donald_O._Hebb.
- Metaplasticity wikiPageWikiLink G_protein-coupled_receptor.
- Metaplasticity wikiPageWikiLink G_protein–coupled_receptor.
- Metaplasticity wikiPageWikiLink Gliotransmitter.
- Metaplasticity wikiPageWikiLink Glutamate.
- Metaplasticity wikiPageWikiLink Glutamate_receptor.
- Metaplasticity wikiPageWikiLink Glutamic_acid.
- Metaplasticity wikiPageWikiLink Hippocampus.
- Metaplasticity wikiPageWikiLink Homeostatic_plasticity.
- Metaplasticity wikiPageWikiLink Hormone.
- Metaplasticity wikiPageWikiLink Inhibitory_postsynaptic_potential.
- Metaplasticity wikiPageWikiLink Ionotropic_receptor.
- Metaplasticity wikiPageWikiLink Learning.
- Metaplasticity wikiPageWikiLink Ligand-gated_ion_channel.
- Metaplasticity wikiPageWikiLink Long-term_Depression.
- Metaplasticity wikiPageWikiLink Long-term_depression.
- Metaplasticity wikiPageWikiLink Long-term_potentiation.
- Metaplasticity wikiPageWikiLink Memory.
- Metaplasticity wikiPageWikiLink N-Methyl-D-aspartic_acid.
- Metaplasticity wikiPageWikiLink NMDA.
- Metaplasticity wikiPageWikiLink NMDA_receptor.
- Metaplasticity wikiPageWikiLink Neuron.
- Metaplasticity wikiPageWikiLink Neuroplasticity.
- Metaplasticity wikiPageWikiLink Plastic_arts.
- Metaplasticity wikiPageWikiLink Silent_synapse.
- Metaplasticity wikiPageWikiLink Supraoptic_nucleus.
- Metaplasticity wikiPageWikiLink Symbolic_system.
- Metaplasticity wikiPageWikiLink Synapse.
- Metaplasticity wikiPageWikiLink Synaptic_plasticity.
- Metaplasticity wikiPageWikiLink Synaptic_tagging.
- Metaplasticity wikiPageWikiLink Tenascin-R.
- Metaplasticity wikiPageWikiLinkText "Metaplasticity".
- Metaplasticity wikiPageWikiLinkText "Metaplasticity#Digital metaplasticity".
- Metaplasticity wikiPageWikiLinkText "Metaplasticity#Synaptic homeostasis".
- Metaplasticity wikiPageWikiLinkText "metaplastic cells".
- Metaplasticity wikiPageWikiLinkText "metaplasticity".
- Metaplasticity hasPhotoCollection Metaplasticity.
- Metaplasticity wikiPageUsesTemplate Template:Reflist.
- Metaplasticity subject Category:Neurophysiology.
- Metaplasticity subject Category:Neuroscience.
- Metaplasticity hypernym Term.
- Metaplasticity comment "Metaplasticity is a term originally coined by W.C. Abraham and M.F. Bear to refer to the plasticity of synaptic plasticity. Until that time synaptic plasticity had referred to the plastic nature of individual synapses. However this new form referred to the plasticity of the plasticity itself, thus the term meta-plasticity. The idea is that the synapse's previous history of activity determines its current plasticity.".
- Metaplasticity label "Metaplasticity".
- Metaplasticity sameAs Metaplastizität.
- Metaplasticity sameAs m.0d1325.
- Metaplasticity sameAs Q1420291.
- Metaplasticity sameAs Q1420291.
- Metaplasticity wasDerivedFrom Metaplasticity?oldid=678963298.
- Metaplasticity isPrimaryTopicOf Metaplasticity.