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- Marius_Sudol abstract "Marius Sudol, PhD, is an American molecular and cellular biologist. He was born in 1954 in Tarnow, Poland. In 1978, he immigrated to the United States to study at The Rockefeller University in New York City. Among his most significant achievements to date are the identification of a modular protein domain, known as the WW domain, and the characterization of its cognate ligands. In 2004, together with a research team at AxCell-Cytogen company, Marius Sudol reported the first comprehensive protein interaction map for a human modular domain. Today, the WW domain is known to mediate critical signals in tumor suppressor networks, including the Hippo signaling pathway. More importantly, syndromes such as the Golabi-Ito-Hall syndrome of intellectual disability and Liddle syndrome of hypertension are caused by loss-of-function point mutations in the WW domain or its cognate ligands. The research conducted in Marius Sudol’s laboratory and those of his collaborators over the past two decades has directly contributed to a systems biology level understanding of signaling networks from the perspective of modular protein domains. As a co-founder and co-leader of the Protein Modules Consortium, he advocates systems biology approaches and synthetic biology strategies in designing therapeutic interventions based on the knowledge of the structure and function of protein modules.Over the course of his scientific career spanning more than three decades, Marius Sudol has authored 150 publications, including original research articles and invited reviews in refereed journals as well as numerous book chapters. These publications have been collectively cited over 12,000 times. His current work focuses on the role of WW domain-containing proteins in the Hippo tumor suppressor network and Golabi-Ito-Hall syndrome of intellectual disability.".
- Marius_Sudol academicAdvisor Andrzej_Klein,_Edward_Reich,_Wolf-Dieter_Schleuning,_Hidesaburo_Hanafusa,_Paul_Klotman.
- Marius_Sudol almaMater The_Rockefeller_University_(New_York_City).
- Marius_Sudol birthDate "1954-11-15".
- Marius_Sudol birthPlace Poland.
- Marius_Sudol birthPlace Tarnów.
- Marius_Sudol field Molecular_and_Cellular_Biology.
- Marius_Sudol knownFor Signal_transduction.
- Marius_Sudol nationality United_States.
- Marius_Sudol thumbnail Marius_Sudol_in_2008.jpg?width=300.
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- Marius_Sudol wikiPageWikiLink Andrzej_Klein,_Edward_Reich,_Wolf-Dieter_Schleuning,_Hidesaburo_Hanafusa,_Paul_Klotman.
- Marius_Sudol wikiPageWikiLink Category:1954_births.
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- Marius_Sudol wikiPageWikiLink Category:Molecular_biologists.
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- Marius_Sudol wikiPageWikiLink Geisinger_Clinic_(PA).
- Marius_Sudol wikiPageWikiLink Molecular_&_Cellular_Biology.
- Marius_Sudol wikiPageWikiLink Molecular_and_Cellular_Biology.
- Marius_Sudol wikiPageWikiLink Mount_Sinai_School_of_Medicine_(NY).
- Marius_Sudol wikiPageWikiLink National_University_of_Singapore_(Republic_of_Singapore).
- Marius_Sudol wikiPageWikiLink Poland.
- Marius_Sudol wikiPageWikiLink Signal_transduction.
- Marius_Sudol wikiPageWikiLink Tarnów.
- Marius_Sudol wikiPageWikiLink The_Rockefeller_University_(New_York_City).
- Marius_Sudol academicAdvisors Andrzej_Klein,_Edward_Reich,_Wolf-Dieter_Schleuning,_Hidesaburo_Hanafusa,_Paul_Klotman.
- Marius_Sudol almaMater The_Rockefeller_University_(New_York_City).
- Marius_Sudol birthDate "1954-11-15".
- Marius_Sudol birthPlace Poland.
- Marius_Sudol birthPlace Tarnów.
- Marius_Sudol born "1954".
- Marius_Sudol field Molecular_&_Cellular_Biology.
- Marius_Sudol field Molecular_and_Cellular_Biology.
- Marius_Sudol hasPhotoCollection Marius_Sudol.
- Marius_Sudol knownFor Signal_transduction.
- Marius_Sudol name "Marius Sudol, PhD".
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- Marius_Sudol workInstitutions Geisinger_Clinic_(PA).
- Marius_Sudol workInstitutions Mount_Sinai_School_of_Medicine_(NY).
- Marius_Sudol workInstitutions National_University_of_Singapore_(Republic_of_Singapore).
- Marius_Sudol subject Category:1954_births.
- Marius_Sudol subject Category:Living_people.
- Marius_Sudol subject Category:Molecular_biologists.
- Marius_Sudol subject Category:People_from_Tarnów.
- Marius_Sudol hypernym Biologist.
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- Marius_Sudol comment "Marius Sudol, PhD, is an American molecular and cellular biologist. He was born in 1954 in Tarnow, Poland. In 1978, he immigrated to the United States to study at The Rockefeller University in New York City. Among his most significant achievements to date are the identification of a modular protein domain, known as the WW domain, and the characterization of its cognate ligands.".
- Marius_Sudol label "Marius Sudol".
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- Marius_Sudol depiction Marius_Sudol_in_2008.jpg.
- Marius_Sudol isPrimaryTopicOf Marius_Sudol.
- Marius_Sudol name "Marius Sudol, PhD".