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- M_protein_(Streptococcus) abstract "M protein is a virulence factor that can be produced by certain species of Streptococcus.Viruses, parasites and bacteria are covered in protein and sugar molecules that help them gain entry into a host by counteracting the host's defences. One such molecule is the M protein produced by certain streptococcal bacteria. M proteins embody a motif that is now known to be shared by many Gram-positive bacterial surface proteins. The motif includes a conserved pentapeptide LPXTG, which precedes a hydrophobic C-terminal membrane anchor, which itself precedes a cluster of basic residues.M protein is strongly anti-phagocytic and is a major virulence factor. It binds to serum factor H, destroying C3-convertase and preventing opsonization by C3b. However plasma B cells can generate antibodies against M protein which will help in opsonization and further the destruction of the microorganism by the macrophages and neutrophilis. Cross-reactivity of anti-M protein antibodies with heart muscle has been suggested to be the basis for rheumatic fever.It was originally identified by Rebecca Lancefield, who also formulated the Lancefield classification system for streptococcal bacteria. Bacteria like S. pyogenes, which possess M protein are classified in group A of the Lancefield system.".
- M_protein_(Streptococcus) symbol "Gram_pos_anchor".
- M_protein_(Streptococcus) wikiPageID "20130800".
- M_protein_(Streptococcus) wikiPageLength "4030".
- M_protein_(Streptococcus) wikiPageOutDegree "28".
- M_protein_(Streptococcus) wikiPageRevisionID "679491985".
- M_protein_(Streptococcus) wikiPageWikiLink Bacteria.
- M_protein_(Streptococcus) wikiPageWikiLink Bacterium.
- M_protein_(Streptococcus) wikiPageWikiLink Base_(chemistry).
- M_protein_(Streptococcus) wikiPageWikiLink C3-convertase.
- M_protein_(Streptococcus) wikiPageWikiLink C3b.
- M_protein_(Streptococcus) wikiPageWikiLink Category:Streptococcal_proteins.
- M_protein_(Streptococcus) wikiPageWikiLink Category:Virulence_factors.
- M_protein_(Streptococcus) wikiPageWikiLink Cell_membrane.
- M_protein_(Streptococcus) wikiPageWikiLink Conserved_sequence.
- M_protein_(Streptococcus) wikiPageWikiLink Cross-reactivity.
- M_protein_(Streptococcus) wikiPageWikiLink Factor_H.
- M_protein_(Streptococcus) wikiPageWikiLink Gram-positive.
- M_protein_(Streptococcus) wikiPageWikiLink Gram-positive_bacteria.
- M_protein_(Streptococcus) wikiPageWikiLink Hydrophobe.
- M_protein_(Streptococcus) wikiPageWikiLink Hydrophobic.
- M_protein_(Streptococcus) wikiPageWikiLink Molecule.
- M_protein_(Streptococcus) wikiPageWikiLink Opsonin.
- M_protein_(Streptococcus) wikiPageWikiLink Opsonization.
- M_protein_(Streptococcus) wikiPageWikiLink Parasite.
- M_protein_(Streptococcus) wikiPageWikiLink Parasitism.
- M_protein_(Streptococcus) wikiPageWikiLink Protein.
- M_protein_(Streptococcus) wikiPageWikiLink Protein_motif.
- M_protein_(Streptococcus) wikiPageWikiLink Proteins.
- M_protein_(Streptococcus) wikiPageWikiLink Rebecca_Lancefield.
- M_protein_(Streptococcus) wikiPageWikiLink Residue_(chemistry).
- M_protein_(Streptococcus) wikiPageWikiLink Rheumatic_fever.
- M_protein_(Streptococcus) wikiPageWikiLink Sequence_motif.
- M_protein_(Streptococcus) wikiPageWikiLink Streptococcus.
- M_protein_(Streptococcus) wikiPageWikiLink Structural_motif.
- M_protein_(Streptococcus) wikiPageWikiLink Sugar.
- M_protein_(Streptococcus) wikiPageWikiLink Virulence_factor.
- M_protein_(Streptococcus) wikiPageWikiLink Zinc-dependent_phospholipase_C.
- M_protein_(Streptococcus) wikiPageWikiLink Zinc_dependent_phospholipase_C.
- M_protein_(Streptococcus) wikiPageWikiLinkText "M protein (Streptococcus)".
- M_protein_(Streptococcus) wikiPageWikiLinkText "M protein".
- M_protein_(Streptococcus) wikiPageWikiLinkText "Streptococcal M protein".
- M_protein_(Streptococcus) hasPhotoCollection M_protein_(Streptococcus).
- M_protein_(Streptococcus) interpro "IPR019948".
- M_protein_(Streptococcus) name "Gram_pos_anchor".
- M_protein_(Streptococcus) pfam "PF00746".
- M_protein_(Streptococcus) pfamClan "CL0501".
- M_protein_(Streptococcus) prosite "PDOC00373".
- M_protein_(Streptococcus) symbol "Gram_pos_anchor".
- M_protein_(Streptococcus) wikiPageUsesTemplate Template:Cite_journal.
- M_protein_(Streptococcus) wikiPageUsesTemplate Template:Distinguish.
- M_protein_(Streptococcus) wikiPageUsesTemplate Template:Infobox_protein_family.
- M_protein_(Streptococcus) wikiPageUsesTemplate Template:Reflist.
- M_protein_(Streptococcus) subject Category:Streptococcal_proteins.
- M_protein_(Streptococcus) subject Category:Virulence_factors.
- M_protein_(Streptococcus) hypernym Factor.
- M_protein_(Streptococcus) type Biomolecule.
- M_protein_(Streptococcus) type Protein.
- M_protein_(Streptococcus) type Thing.
- M_protein_(Streptococcus) type Q206229.
- M_protein_(Streptococcus) type Q8054.
- M_protein_(Streptococcus) comment "M protein is a virulence factor that can be produced by certain species of Streptococcus.Viruses, parasites and bacteria are covered in protein and sugar molecules that help them gain entry into a host by counteracting the host's defences. One such molecule is the M protein produced by certain streptococcal bacteria. M proteins embody a motif that is now known to be shared by many Gram-positive bacterial surface proteins.".
- M_protein_(Streptococcus) label "M protein (Streptococcus)".
- M_protein_(Streptococcus) differentFrom Protein_M.
- M_protein_(Streptococcus) sameAs Proteína_M_(Streptococcus).
- M_protein_(Streptococcus) sameAs m.04ydw2j.
- M_protein_(Streptococcus) sameAs Q10354652.
- M_protein_(Streptococcus) sameAs Q10354652.
- M_protein_(Streptococcus) wasDerivedFrom M_protein_(Streptococcus)?oldid=679491985.
- M_protein_(Streptococcus) isPrimaryTopicOf M_protein_(Streptococcus).