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- MG132 abstract "MG132 is a specific, potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). It reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. MG132 activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis. MG132 also inhibits NF-κB activation with an IC50 of 3 µM and prevents β-secretase cleavage.".
- MG132 thumbnail MG132.png?width=300.
- MG132 wikiPageExternalLink mg-132.html?picat=&q=mg132.
- MG132 wikiPageExternalLink p_w_.b.s1LzxMAAAEW02EfVhTm.
- MG132 wikiPageID "21516484".
- MG132 wikiPageLength "1968".
- MG132 wikiPageOutDegree "10".
- MG132 wikiPageRevisionID "683757177".
- MG132 wikiPageWikiLink ATPase.
- MG132 wikiPageWikiLink Apoptosis.
- MG132 wikiPageWikiLink Beta-secretase_1.
- MG132 wikiPageWikiLink C-Jun_N-terminal_kinase.
- MG132 wikiPageWikiLink C-Jun_N-terminal_kinases.
- MG132 wikiPageWikiLink Category:Peptides.
- MG132 wikiPageWikiLink Enzyme_inhibitor.
- MG132 wikiPageWikiLink Inhibition_constant.
- MG132 wikiPageWikiLink Isopeptidase.
- MG132 wikiPageWikiLink NF-κB.
- MG132 wikiPageWikiLink Proteasome_inhibitor.
- MG132 wikiPageWikiLink Ubiquitin.
- MG132 wikiPageWikiLinkText "MG132".
- MG132 hasPhotoCollection MG132.
- MG132 imagefile "MG132.png".
- MG132 othernames "N-leucinylleucinylleucinal".
- MG132 othernames "Z-Leu-Leu-Leu-al".
- MG132 verifiedfields "changed".
- MG132 verifiedrevid "446613982".
- MG132 watchedfields "changed".
- MG132 wikiPageUsesTemplate Template:Chembox.
- MG132 subject Category:Peptides.
- MG132 hypernym Inhibitor.
- MG132 type Article.
- MG132 type Biomolecule.
- MG132 type ChemicalCompound.
- MG132 type ChemicalSubstance.
- MG132 type Article.
- MG132 type Biomolecule.
- MG132 type Chemical.
- MG132 type Peptide.
- MG132 type ChemicalObject.
- MG132 type Thing.
- MG132 type Q11173.
- MG132 comment "MG132 is a specific, potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). It reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. MG132 activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis. MG132 also inhibits NF-κB activation with an IC50 of 3 µM and prevents β-secretase cleavage.".
- MG132 label "MG132".
- MG132 sameAs MG132.
- MG132 sameAs m.05h4prd.
- MG132 sameAs MG132.
- MG132 sameAs Q3272916.
- MG132 sameAs Q3272916.
- MG132 wasDerivedFrom MG132?oldid=683757177.
- MG132 depiction MG132.png.
- MG132 isPrimaryTopicOf MG132.