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- MDia1 abstract "mDia1 (also known as Dia1, Drf1 for Diaphanous-related formin-1, Diaph1, KIAA4062, p140mDia, mKIAA4062, D18Wsu154e) is a protein. It is the mouse version of the diaphanous homolog 1 of Drosophila. It belongs to the protein family called the formins and is a Rho effector. It localizes to the mitotic spindle and midbody, plays a role in stress fiber and filopodia formation, phagocytosis, activation of serum response factor, a transcription factor, and formation of adherens junction. mDia1 accelerates actin nucleation and elongation by interacting with barbed ends (fast-growing ends) of actin filaments. The gene encoding mDia1 is located on Chromosome 18 of Mus musculus and named Diap1.mDia1 is highly homologous to Drosophila diaphanous, regulating the cytokinetic ring during cytokinesis. Homologues in other species are known as well, like the human DIAP1, budding yeast's Bni1 or Cdc12p of S. pombe.The gene has been knocked-out in mice.".
- MDia1 pdb "1z2c".
- MDia1 refseq "NP_031884.1".
- MDia1 symbol "DRF1".
- MDia1 symbol "mDia1".
- MDia1 thumbnail 1z2c_asr_r_500.jpeg?width=300.
- MDia1 uniprot "o08808".
- MDia1 wikiPageExternalLink www.pdb.org.
- MDia1 wikiPageID "27405535".
- MDia1 wikiPageLength "14882".
- MDia1 wikiPageOutDegree "50".
- MDia1 wikiPageRevisionID "674581570".
- MDia1 wikiPageWikiLink Actin.
- MDia1 wikiPageWikiLink Actin_filament.
- MDia1 wikiPageWikiLink Actin_filaments.
- MDia1 wikiPageWikiLink Amino_acid.
- MDia1 wikiPageWikiLink Amino_acids.
- MDia1 wikiPageWikiLink 3_complex.
- MDia1 wikiPageWikiLink CDNA.
- MDia1 wikiPageWikiLink Category:Animal_proteins.
- MDia1 wikiPageWikiLink Category:Cell_cycle.
- MDia1 wikiPageWikiLink Category:Genes_mutated_in_mice.
- MDia1 wikiPageWikiLink Cell_adhesion.
- MDia1 wikiPageWikiLink Complementary_DNA.
- MDia1 wikiPageWikiLink DIAPH1.
- MDia1 wikiPageWikiLink Endocytosis.
- MDia1 wikiPageWikiLink Endosome.
- MDia1 wikiPageWikiLink Endosomes.
- MDia1 wikiPageWikiLink FH1.
- MDia1 wikiPageWikiLink Formin.
- MDia1 wikiPageWikiLink Formins.
- MDia1 wikiPageWikiLink GTPase.
- MDia1 wikiPageWikiLink IQGAP1.
- MDia1 wikiPageWikiLink Macrophage.
- MDia1 wikiPageWikiLink Macrophages.
- MDia1 wikiPageWikiLink Microfilament.
- MDia1 wikiPageWikiLink Microtubule.
- MDia1 wikiPageWikiLink Nucleation.
- MDia1 wikiPageWikiLink Polymerization.
- MDia1 wikiPageWikiLink Premature_ovarian_failure.
- MDia1 wikiPageWikiLink Profilin.
- MDia1 wikiPageWikiLink Protein_dimer.
- MDia1 wikiPageWikiLink Protein_filament.
- MDia1 wikiPageWikiLink Rho.
- MDia1 wikiPageWikiLink Rho_family_of_GTPases.
- MDia1 wikiPageWikiLink Stress_fiber.
- MDia1 wikiPageWikiLink Tubulin.
- MDia1 wikiPageWikiLink Two-hybrid_screening.
- MDia1 wikiPageWikiLink Wiktionary:Elongation.
- MDia1 wikiPageWikiLink Yeast_two-hybrid.
- MDia1 wikiPageWikiLink File:Mdia1_domains.jpg.
- MDia1 wikiPageWikiLinkText "mDia1".
- MDia1 altsymbols "DRF1".
- MDia1 caption "Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP".
- MDia1 hasPhotoCollection MDia1.
- MDia1 name "Protein diaphanous homolog 1".
- MDia1 pdb "1".
- MDia1 refseq "NP_031884.1".
- MDia1 symbol "mDia1".
- MDia1 uniprot "o08808".
- MDia1 wikiPageUsesTemplate Template:Infobox_protein.
- MDia1 wikiPageUsesTemplate Template:Reflist.
- MDia1 subject Category:Animal_proteins.
- MDia1 subject Category:Cell_cycle.
- MDia1 subject Category:Genes_mutated_in_mice.
- MDia1 hypernym Protein.
- MDia1 type Article.
- MDia1 type Biomolecule.
- MDia1 type Protein.
- MDia1 type Article.
- MDia1 type Biomolecule.
- MDia1 type Chemical.
- MDia1 type Nutrient.
- MDia1 type Thing.
- MDia1 type Q206229.
- MDia1 type Q8054.
- MDia1 comment "mDia1 (also known as Dia1, Drf1 for Diaphanous-related formin-1, Diaph1, KIAA4062, p140mDia, mKIAA4062, D18Wsu154e) is a protein. It is the mouse version of the diaphanous homolog 1 of Drosophila. It belongs to the protein family called the formins and is a Rho effector. It localizes to the mitotic spindle and midbody, plays a role in stress fiber and filopodia formation, phagocytosis, activation of serum response factor, a transcription factor, and formation of adherens junction.".
- MDia1 label "MDia1".
- MDia1 sameAs m.0cmcq4w.
- MDia1 sameAs Q6715229.
- MDia1 sameAs Q6715229.
- MDia1 wasDerivedFrom MDia1?oldid=674581570.
- MDia1 depiction 1z2c_asr_r_500.jpeg.
- MDia1 isPrimaryTopicOf MDia1.
- MDia1 name "Protein diaphanous homolog 1".