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- Lipid_droplet abstract "Lipid droplets, also referred to as lipid bodies, oil bodies or adiposomes, are lipid-rich cellular organelles that regulate the storage and hydrolysis of neutral lipids and are found largely in the adipose tissue. They also serve as a reservoir for cholesterol and acyl-glycerols for membrane formation and maintenance. Lipid droplets are found in all eukaryotic organisms and store a large portion of lipids in mammalian adipocytes. Initially, these lipid droplets were considered to merely serve as fat depots, but since the discovery in the nineties of proteins in the lipid droplet coat that regulate lipid droplet dynamics and lipid metabolism, lipid droplets are seen as highly dynamic organelles that play a very important role in the regulation of intracellular lipid storage and lipid metabolism.The role of lipid droplets outside of lipid and cholesterol storage has recently begun to be elucidated and includes a close association to inflammatory responses through the synthesis and metabolism of eicosanoids and to metabolic disorders such as obesity, cancer, and atherosclerosis. In non-adipocytes, lipid droplets are known to play a role in protection from lipotoxicity by storage of fatty acids in the form of neutral triacylglycerol, which consists of three fatty acids bound to glycerol. Alternatively, fatty acids can be converted to lipid intermediates like diacylglycerol (DAG), ceramides and fatty acyl-CoAs. These lipid intermediates can impair insulin signaling, which is referred to as lipid-induced insulin resistance and lipotoxicity. Lipid droplets also serve as platforms for protein binding and degradation. Finally, lipid droplets are known to be exploited by pathogens such as the hepatitis C virus, the dengue virus and chlamydia trachomatis among others.".
- Lipid_droplet wikiPageID "26269215".
- Lipid_droplet wikiPageLength "11462".
- Lipid_droplet wikiPageOutDegree "40".
- Lipid_droplet wikiPageRevisionID "678787288".
- Lipid_droplet wikiPageWikiLink Adipocyte.
- Lipid_droplet wikiPageWikiLink Arachidonic_acid.
- Lipid_droplet wikiPageWikiLink Category:Biochemistry.
- Lipid_droplet wikiPageWikiLink Category:Metabolism.
- Lipid_droplet wikiPageWikiLink Chlamydia_trachomatis.
- Lipid_droplet wikiPageWikiLink Cholesterol.
- Lipid_droplet wikiPageWikiLink Cytokine.
- Lipid_droplet wikiPageWikiLink Cytokines.
- Lipid_droplet wikiPageWikiLink Dengue_virus.
- Lipid_droplet wikiPageWikiLink Diglyceride_acyltransferase.
- Lipid_droplet wikiPageWikiLink Eicosanoid.
- Lipid_droplet wikiPageWikiLink Eicosanoids.
- Lipid_droplet wikiPageWikiLink Endoplasmic_reticulum.
- Lipid_droplet wikiPageWikiLink Fatty_acid.
- Lipid_droplet wikiPageWikiLink File:Lipid_droplet_structure.tif.
- Lipid_droplet wikiPageWikiLink Growth_factor.
- Lipid_droplet wikiPageWikiLink Hepatitis_C_virus.
- Lipid_droplet wikiPageWikiLink Hydrolysis.
- Lipid_droplet wikiPageWikiLink Lipid.
- Lipid_droplet wikiPageWikiLink Lipid_bilayer.
- Lipid_droplet wikiPageWikiLink Lipid_metabolism.
- Lipid_droplet wikiPageWikiLink Lipids.
- Lipid_droplet wikiPageWikiLink Lipolysis.
- Lipid_droplet wikiPageWikiLink Lipopolysaccharide.
- Lipid_droplet wikiPageWikiLink Lipotoxicity.
- Lipid_droplet wikiPageWikiLink Nardia.
- Lipid_droplet wikiPageWikiLink Obesity.
- Lipid_droplet wikiPageWikiLink Oil_body.
- Lipid_droplet wikiPageWikiLink Oleic_acid.
- Lipid_droplet wikiPageWikiLink Organelle.
- Lipid_droplet wikiPageWikiLink Perilipin.
- Lipid_droplet wikiPageWikiLink Phosphatidylcholine.
- Lipid_droplet wikiPageWikiLink Phosphatidylethanolamine.
- Lipid_droplet wikiPageWikiLink Phosphatidylinositol.
- Lipid_droplet wikiPageWikiLink Platelet-activating_factor.
- Lipid_droplet wikiPageWikiLink Proteomics.
- Lipid_droplet wikiPageWikiLink SNARE_(protein).
- Lipid_droplet wikiPageWikiLink Triglyceride.
- Lipid_droplet wikiPageWikiLink Unsaturated_fat.
- Lipid_droplet wikiPageWikiLinkText "Lipid droplet".
- Lipid_droplet wikiPageWikiLinkText "fat droplet".
- Lipid_droplet wikiPageWikiLinkText "lipid droplet".
- Lipid_droplet wikiPageWikiLinkText "lipid droplets".
- Lipid_droplet hasPhotoCollection Lipid_droplet.
- Lipid_droplet wikiPageUsesTemplate Template:Reflist.
- Lipid_droplet wikiPageUsesTemplate Template:Technical.
- Lipid_droplet subject Category:Biochemistry.
- Lipid_droplet subject Category:Metabolism.
- Lipid_droplet hypernym Organelles.
- Lipid_droplet type AnatomicalStructure.
- Lipid_droplet type Process.
- Lipid_droplet comment "Lipid droplets, also referred to as lipid bodies, oil bodies or adiposomes, are lipid-rich cellular organelles that regulate the storage and hydrolysis of neutral lipids and are found largely in the adipose tissue. They also serve as a reservoir for cholesterol and acyl-glycerols for membrane formation and maintenance. Lipid droplets are found in all eukaryotic organisms and store a large portion of lipids in mammalian adipocytes.".
- Lipid_droplet label "Lipid droplet".
- Lipid_droplet sameAs Lipid_droplet.
- Lipid_droplet sameAs Lipid_Droplets.
- Lipid_droplet sameAs m.0n5268y.
- Lipid_droplet sameAs Q573950.
- Lipid_droplet sameAs Q573950.
- Lipid_droplet wasDerivedFrom Lipid_droplet?oldid=678787288.
- Lipid_droplet isPrimaryTopicOf Lipid_droplet.