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- Lamellar_phase abstract "Lamellar phase refers generally to packing of polar-headed long chain nonpolar-tail molecules in an environment of bulk polar liquid, as sheets of bilayers separated by bulk liquid. In biophysics, polar lipids (mostly, phospholipids, and rarely, glycolipids) pack as a liquid crystalline bilayer, with hydrophobic fatty acyl long chains directed inwardly and polar headgroups of lipids aligned on the outside in contact with water, as a 2-dimensional flat sheet surface. Under transmission electron microscope (TEM), after staining with polar headgroup reactive chemical osmium tetroxide, lamellar lipid phase appears as two thin parallel dark staining lines/sheets, constituted by aligned polar headgroups of lipids. 'Sandwiched' between these two parallel lines, there exists one thicker line/sheet of non-staining closely packed layer of long lipid fatty acyl chains. This TEM-appearance became famous as Robertson's unit membrane - the basis of all biological membranes, and structure of lipid bilayer in unilamellar liposomes. In multilamellar liposomes, many such lipid bilayer sheets are layered concentrically with water layers in between.In lamellar lipid bilayers, polar headgroups of lipids align together at the interface of water and hydrophobic fatty-acid acyl chains align parallel to one another 'hiding away' from water. The lipid head groups are somewhat more 'tightly' packed than relatively 'fluid' hydrocarbon fatty acyl long chains. The lamellar lipid bilayer organization, thus reveals a 'flexibility gradient' of increasing freedom of motions from near the head-groups towards the terminal fatty-acyl chain methyl groups. Existence of such a dynamic organization of lamellar phase in liposomes as well as biological membranes can be confirmed by spin label electron paramagnetic resonance and high resolution nuclear magnetic resonance spectroscopy studies of biological membranes and liposomes.In 'soft matter science', where physics and chemistry meet biological science, a bilayer lamellar phase has been recently created from fluorinated silica, and it has been projected for use as a shear-thinning lubricant.".
- Lamellar_phase thumbnail Lamellar_phase_lipids_(original_research_work_of_Dr._R.C._YashRoy).jpg?width=300.
- Lamellar_phase wikiPageExternalLink watch?v=9ILSsW3tXr8.
- Lamellar_phase wikiPageExternalLink watch?v=lm-dAvbl330.
- Lamellar_phase wikiPageID "43275893".
- Lamellar_phase wikiPageLength "3704".
- Lamellar_phase wikiPageOutDegree "29".
- Lamellar_phase wikiPageRevisionID "664995204".
- Lamellar_phase wikiPageWikiLink Acyl.
- Lamellar_phase wikiPageWikiLink Bilayer.
- Lamellar_phase wikiPageWikiLink Biological_membrane.
- Lamellar_phase wikiPageWikiLink Biological_membranes.
- Lamellar_phase wikiPageWikiLink Biophysics.
- Lamellar_phase wikiPageWikiLink Category:Liquid_crystals.
- Lamellar_phase wikiPageWikiLink Category:Membrane_biology.
- Lamellar_phase wikiPageWikiLink Chemical_polarity.
- Lamellar_phase wikiPageWikiLink Electron_paramagnetic_resonance.
- Lamellar_phase wikiPageWikiLink Fatty-acid.
- Lamellar_phase wikiPageWikiLink Fatty_acid.
- Lamellar_phase wikiPageWikiLink Glycolipid.
- Lamellar_phase wikiPageWikiLink Glycolipids.
- Lamellar_phase wikiPageWikiLink History_of_cell_membrane_theory.
- Lamellar_phase wikiPageWikiLink Hydrophobe.
- Lamellar_phase wikiPageWikiLink Hydrophobic.
- Lamellar_phase wikiPageWikiLink Lipid.
- Lamellar_phase wikiPageWikiLink Lipid_bilayer.
- Lamellar_phase wikiPageWikiLink Liposome.
- Lamellar_phase wikiPageWikiLink Liposomes.
- Lamellar_phase wikiPageWikiLink Liquid_crystal.
- Lamellar_phase wikiPageWikiLink Lubricant.
- Lamellar_phase wikiPageWikiLink Molecule.
- Lamellar_phase wikiPageWikiLink Nuclear_magnetic_resonance.
- Lamellar_phase wikiPageWikiLink Osmium_tetroxide.
- Lamellar_phase wikiPageWikiLink Phospholipid.
- Lamellar_phase wikiPageWikiLink Phospholipids.
- Lamellar_phase wikiPageWikiLink Spectroscopy.
- Lamellar_phase wikiPageWikiLink Spin_label.
- Lamellar_phase wikiPageWikiLink Transmission_electron_microscope.
- Lamellar_phase wikiPageWikiLink Transmission_electron_microscopy.
- Lamellar_phase wikiPageWikiLink Unilamellar_liposome.
- Lamellar_phase wikiPageWikiLink File:Lamellar_phase_lipids_(original_research_work_of_Dr._R.C._YashRoy).jpg.
- Lamellar_phase wikiPageWikiLinkText "Lamellar phase".
- Lamellar_phase wikiPageWikiLinkText "lamellar phase".
- Lamellar_phase hasPhotoCollection Lamellar_phase.
- Lamellar_phase wikiPageUsesTemplate Template:Reflist.
- Lamellar_phase subject Category:Liquid_crystals.
- Lamellar_phase subject Category:Membrane_biology.
- Lamellar_phase comment "Lamellar phase refers generally to packing of polar-headed long chain nonpolar-tail molecules in an environment of bulk polar liquid, as sheets of bilayers separated by bulk liquid. In biophysics, polar lipids (mostly, phospholipids, and rarely, glycolipids) pack as a liquid crystalline bilayer, with hydrophobic fatty acyl long chains directed inwardly and polar headgroups of lipids aligned on the outside in contact with water, as a 2-dimensional flat sheet surface.".
- Lamellar_phase label "Lamellar phase".
- Lamellar_phase sameAs m.0114kyn6.
- Lamellar_phase sameAs Q18344920.
- Lamellar_phase sameAs Q18344920.
- Lamellar_phase wasDerivedFrom Lamellar_phase?oldid=664995204.
- Lamellar_phase depiction Lamellar_phase_lipids_(original_research_work_of_Dr._R.C._YashRoy).jpg.
- Lamellar_phase isPrimaryTopicOf Lamellar_phase.