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- Lactose_permease abstract "Lactose permease is a membrane protein which is a member of the major facilitator superfamily. Lactose permease can be classified as a symporter, which uses the proton gradient towards the cell to transport β-galactosides such as lactose in the same direction into the cell.The protein has twelve transmembrane helices and exhibits an internal two-fold symmetry, relating the N-terminal six helices onto the C-terminal helices. It is encoded by the lacY gene in the lac operon.The sugar lies in a pocket in the center of the protein which is accessible from the periplasm. On binding, a large conformational change takes place which makes the sugar binding site accessible from the cytoplasm. Mechanism: hydrogen from the outside of the cell binds to a carboxyl group on the enzyme that allows it to undergo a conformational change. This form of lactose permease can bind lactose from outside the cell. The enzyme then everts and lactose is transported inward.The X-ray crystal structure was first solved in 2003 by J. Abramson et al.".
- Lactose_permease symbol "LacY_symp".
- Lactose_permease thumbnail 2y5y.png?width=300.
- Lactose_permease wikiPageID "24481328".
- Lactose_permease wikiPageLength "2721".
- Lactose_permease wikiPageOutDegree "10".
- Lactose_permease wikiPageRevisionID "678212826".
- Lactose_permease wikiPageWikiLink Category:Transmembrane_proteins.
- Lactose_permease wikiPageWikiLink Category:Transport_proteins.
- Lactose_permease wikiPageWikiLink Electrochemical_gradient.
- Lactose_permease wikiPageWikiLink Galactoside.
- Lactose_permease wikiPageWikiLink Lac_operon.
- Lactose_permease wikiPageWikiLink Lactose.
- Lactose_permease wikiPageWikiLink Major_facilitator_family.
- Lactose_permease wikiPageWikiLink Major_facilitator_superfamily.
- Lactose_permease wikiPageWikiLink Symporter.
- Lactose_permease wikiPageWikiLink Transmembrane_domain.
- Lactose_permease wikiPageWikiLink Transmembrane_helix.
- Lactose_permease wikiPageWikiLink X-ray_crystal_structure.
- Lactose_permease wikiPageWikiLink X-ray_crystallography.
- Lactose_permease wikiPageWikiLinkText "Lactose permease".
- Lactose_permease wikiPageWikiLinkText "lactose permease".
- Lactose_permease wikiPageWikiLinkText "lactose permease's".
- Lactose_permease caption "Crystal Structure of Lactose Permease in Complex with an Affinity Inactivator. PDB".
- Lactose_permease hasPhotoCollection Lactose_permease.
- Lactose_permease interpro "IPR022814".
- Lactose_permease name "LacY proton/sugar symporter".
- Lactose_permease opmFamily "15".
- Lactose_permease opmProtein "2".
- Lactose_permease pfam "PF01306".
- Lactose_permease pfamClan "CL0015".
- Lactose_permease prosite "PDOC00698".
- Lactose_permease symbol "LacY_symp".
- Lactose_permease tcdb "2".
- Lactose_permease wikiPageUsesTemplate Template:Infobox_protein_family.
- Lactose_permease wikiPageUsesTemplate Template:Protein-stub.
- Lactose_permease wikiPageUsesTemplate Template:Reflist.
- Lactose_permease subject Category:Transmembrane_proteins.
- Lactose_permease subject Category:Transport_proteins.
- Lactose_permease hypernym Protein.
- Lactose_permease type Biomolecule.
- Lactose_permease type Protein.
- Lactose_permease type Chemical.
- Lactose_permease type Thing.
- Lactose_permease type Q206229.
- Lactose_permease type Q8054.
- Lactose_permease comment "Lactose permease is a membrane protein which is a member of the major facilitator superfamily. Lactose permease can be classified as a symporter, which uses the proton gradient towards the cell to transport β-galactosides such as lactose in the same direction into the cell.The protein has twelve transmembrane helices and exhibits an internal two-fold symmetry, relating the N-terminal six helices onto the C-terminal helices.".
- Lactose_permease label "Lactose permease".
- Lactose_permease sameAs Lactosa_permeasa.
- Lactose_permease sameAs LacY.
- Lactose_permease sameAs m.080f72s.
- Lactose_permease sameAs Q3214686.
- Lactose_permease sameAs Q3214686.
- Lactose_permease wasDerivedFrom Lactose_permease?oldid=678212826.
- Lactose_permease depiction 2y5y.png.
- Lactose_permease isPrimaryTopicOf Lactose_permease.