Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/La_domain> ?p ?o }
Showing triples 1 to 90 of
90
with 100 triples per page.
- La_domain abstract "In molecular biology, the La domain is a conserved protein domain.Human 60 kDa SS-A/Ro ribonucleoproteins (RNPs) are composed of one of the four small Y RNAs and at least two proteins, Ro60 and La. The La protein is a 47 kDa polypeptide that frequently acts as an autoantigen in systemic lupus erythematosus and Sjogren's syndrome. In the nucleus, La acts as a RNA polymerase III (RNAP III) transcription factor, while in the cytoplasm, La acts as a translation factor. In the nucleus, La binds to the 3'UTR of nascent RNAP III transcripts to assist in folding and maturation. In the cytoplasm, La recognises specific classes of mRNAs that contain a 5'-terminal oligopyrimidine (5'TOP) motif known to control protein synthesis. The specific recognition is mediated by the N-terminal domain of La, which comprises a La motif and an RNA recognition motif (RRM). The La motif adopts an alpha/beta fold that comprises a winged-helix motif.Homologous La domain-containing proteins have been identified in a wide range of organisms except Archaea, bacteria and viruses.".
- La_domain symbol "La".
- La_domain thumbnail PDB_2cqk_EBI.jpg?width=300.
- La_domain wikiPageID "34544873".
- La_domain wikiPageLength "3982".
- La_domain wikiPageOutDegree "34".
- La_domain wikiPageRevisionID "608184303".
- La_domain wikiPageWikiLink 3UTR.
- La_domain wikiPageWikiLink 5_end.
- La_domain wikiPageWikiLink Archaea.
- La_domain wikiPageWikiLink Atomic_mass_unit.
- La_domain wikiPageWikiLink Autoantigen.
- La_domain wikiPageWikiLink Autoimmunity.
- La_domain wikiPageWikiLink Bacteria.
- La_domain wikiPageWikiLink Category:Protein_domains.
- La_domain wikiPageWikiLink Cell_nucleus.
- La_domain wikiPageWikiLink Conserved_sequence.
- La_domain wikiPageWikiLink Cytoplasm.
- La_domain wikiPageWikiLink Directionality_(molecular_biology).
- La_domain wikiPageWikiLink Homo_sapiens.
- La_domain wikiPageWikiLink KDa.
- La_domain wikiPageWikiLink MRNA.
- La_domain wikiPageWikiLink Messenger_RNA.
- La_domain wikiPageWikiLink Molecular_binding.
- La_domain wikiPageWikiLink N-terminal.
- La_domain wikiPageWikiLink N-terminus.
- La_domain wikiPageWikiLink Organism.
- La_domain wikiPageWikiLink Peptide.
- La_domain wikiPageWikiLink Polypeptide.
- La_domain wikiPageWikiLink Protein.
- La_domain wikiPageWikiLink Protein_biosynthesis.
- La_domain wikiPageWikiLink Protein_domain.
- La_domain wikiPageWikiLink Protein_folding.
- La_domain wikiPageWikiLink Proteins.
- La_domain wikiPageWikiLink RNA_polymerase_III.
- La_domain wikiPageWikiLink RNA_recognition_motif.
- La_domain wikiPageWikiLink Ribonucleoprotein.
- La_domain wikiPageWikiLink Ribonucleoproteins.
- La_domain wikiPageWikiLink Sjogren_syndrome_antigen_B.
- La_domain wikiPageWikiLink Sjogrens_syndrome.
- La_domain wikiPageWikiLink Sjxc3xb6grens_syndrome.
- La_domain wikiPageWikiLink Systemic_lupus_erythematosus.
- La_domain wikiPageWikiLink TROVE2.
- La_domain wikiPageWikiLink Three_prime_untranslated_region.
- La_domain wikiPageWikiLink Transcription_(genetics).
- La_domain wikiPageWikiLink Transcription_factor.
- La_domain wikiPageWikiLink Translation_(biology).
- La_domain wikiPageWikiLink Translation_(genetics).
- La_domain wikiPageWikiLink Virus.
- La_domain wikiPageWikiLink Viruses.
- La_domain wikiPageWikiLink Winged-helix.
- La_domain wikiPageWikiLink Winged-helix_transcription_factors.
- La_domain wikiPageWikiLink Y_RNA.
- La_domain wikiPageWikiLinkText "La domain".
- La_domain wikiPageWikiLinkText "La".
- La_domain caption "solution structure of the la domain of c-mpl binding protein".
- La_domain cdd "cd07323".
- La_domain hasPhotoCollection La_domain.
- La_domain interpro "IPR006630".
- La_domain merops "I75".
- La_domain name "La domain".
- La_domain pfam "PF05383".
- La_domain prosite "PDOC00280".
- La_domain scop "2".
- La_domain smart "TSPN".
- La_domain symbol "La".
- La_domain tcdb "1".
- La_domain wikiPageUsesTemplate Template:Infobox_protein_family.
- La_domain wikiPageUsesTemplate Template:InterPro_content.
- La_domain wikiPageUsesTemplate Template:Orphan.
- La_domain wikiPageUsesTemplate Template:Reflist.
- La_domain subject Category:Protein_domains.
- La_domain hypernym Ribonucleoproteins.
- La_domain type Article.
- La_domain type Biomolecule.
- La_domain type Protein.
- La_domain type Article.
- La_domain type Chemical.
- La_domain type Domain.
- La_domain type Thing.
- La_domain type Q206229.
- La_domain type Q8054.
- La_domain comment "In molecular biology, the La domain is a conserved protein domain.Human 60 kDa SS-A/Ro ribonucleoproteins (RNPs) are composed of one of the four small Y RNAs and at least two proteins, Ro60 and La. The La protein is a 47 kDa polypeptide that frequently acts as an autoantigen in systemic lupus erythematosus and Sjogren's syndrome. In the nucleus, La acts as a RNA polymerase III (RNAP III) transcription factor, while in the cytoplasm, La acts as a translation factor.".
- La_domain label "La domain".
- La_domain sameAs m.0j29626.
- La_domain sameAs Q6466106.
- La_domain sameAs Q6466106.
- La_domain wasDerivedFrom La_domain?oldid=608184303.
- La_domain depiction PDB_2cqk_EBI.jpg.
- La_domain isPrimaryTopicOf La_domain.