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- Krüppel_associated_box abstract "The Krüppel associated box (KRAB) domain is a category of transcriptional repression domains present in approximately 400 human zinc finger protein-based transcription factors (KRAB zinc finger proteins). The KRAB domain typically consists of about 75 amino acid residues, while the minimal repression module is approximately 45 amino acid residues. It is predicted to function through protein-protein interactions via two amphipathic helices. The most prominent interacting protein is called TRIM28 initially visualized as SMP1, cloned as KAP1 and TIF1-beta. Substitutions for the conserved residues abolish repression.Over 10 independently encoded KRAB domains have been shown to be effective repressors of transcription, suggesting this activity to be a common property of the domain.".
- Krüppel_associated_box symbol "KRAB".
- Krüppel_associated_box thumbnail KRAB_Domain.png?width=300.
- Krüppel_associated_box wikiPageID "4000401".
- Krüppel_associated_box wikiPageLength "6562".
- Krüppel_associated_box wikiPageOutDegree "17".
- Krüppel_associated_box wikiPageRevisionID "660493676".
- Krüppel_associated_box wikiPageWikiLink Amphipathic.
- Krüppel_associated_box wikiPageWikiLink Amphiphile.
- Krüppel_associated_box wikiPageWikiLink Category:Protein_domains.
- Krüppel_associated_box wikiPageWikiLink HPF4.
- Krüppel_associated_box wikiPageWikiLink HTF10.
- Krüppel_associated_box wikiPageWikiLink HTF34.
- Krüppel_associated_box wikiPageWikiLink Leucine_zipper.
- Krüppel_associated_box wikiPageWikiLink TRIM28.
- Krüppel_associated_box wikiPageWikiLink Tetracycline-controlled_transcriptional_activation.
- Krüppel_associated_box wikiPageWikiLink Tetrapod.
- Krüppel_associated_box wikiPageWikiLink Transcription_(genetics).
- Krüppel_associated_box wikiPageWikiLink Transcription_factor.
- Krüppel_associated_box wikiPageWikiLink ZNF10.
- Krüppel_associated_box wikiPageWikiLink ZNF184.
- Krüppel_associated_box wikiPageWikiLink ZNF43.
- Krüppel_associated_box wikiPageWikiLink ZNF91.
- Krüppel_associated_box wikiPageWikiLink Zinc_finger.
- Krüppel_associated_box wikiPageWikiLink Zinc_finger_protein.
- Krüppel_associated_box wikiPageWikiLinkText "KRAB domain".
- Krüppel_associated_box wikiPageWikiLinkText "KRAB".
- Krüppel_associated_box wikiPageWikiLinkText "Krüppel associated box".
- Krüppel_associated_box caption "KRAB domain".
- Krüppel_associated_box hasPhotoCollection Krüppel_associated_box.
- Krüppel_associated_box interpro "IPR001909".
- Krüppel_associated_box name "Krüppel Associated Box".
- Krüppel_associated_box pdb "A:8-48".
- Krüppel_associated_box pfam "PF01352".
- Krüppel_associated_box prosite "PS50805".
- Krüppel_associated_box scop "1".
- Krüppel_associated_box smart "SM00349".
- Krüppel_associated_box symbol "KRAB".
- Krüppel_associated_box width "200".
- Krüppel_associated_box wikiPageUsesTemplate Template:Biochemistry-stub.
- Krüppel_associated_box wikiPageUsesTemplate Template:Cite_journal.
- Krüppel_associated_box wikiPageUsesTemplate Template:Pfam_box.
- Krüppel_associated_box wikiPageUsesTemplate Template:Refbegin.
- Krüppel_associated_box wikiPageUsesTemplate Template:Refend.
- Krüppel_associated_box wikiPageUsesTemplate Template:Reflist.
- Krüppel_associated_box subject Category:Protein_domains.
- Krüppel_associated_box type Biomolecule.
- Krüppel_associated_box type Protein.
- Krüppel_associated_box type Thing.
- Krüppel_associated_box type Q206229.
- Krüppel_associated_box type Q8054.
- Krüppel_associated_box comment "The Krüppel associated box (KRAB) domain is a category of transcriptional repression domains present in approximately 400 human zinc finger protein-based transcription factors (KRAB zinc finger proteins). The KRAB domain typically consists of about 75 amino acid residues, while the minimal repression module is approximately 45 amino acid residues. It is predicted to function through protein-protein interactions via two amphipathic helices.".
- Krüppel_associated_box label "Krüppel associated box".
- Krüppel_associated_box sameAs m.0bbwbp.
- Krüppel_associated_box sameAs Q6440545.
- Krüppel_associated_box sameAs Q6440545.
- Krüppel_associated_box wasDerivedFrom Krüppel_associated_box?oldid=660493676.
- Krüppel_associated_box depiction KRAB_Domain.png.
- Krüppel_associated_box isPrimaryTopicOf Krüppel_associated_box.