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- KM-233 abstract "KM-233 is a drug which is an analogue of Δ8-tetrahydrocannabinol (THC), the less active but more stable isomer of the active component of Cannabis. km-233 differs from Δ8-THC by the pentyl side chain being replaced by a 1,1-dimethylbenzyl group. It has high binding affinity in vitro for both the CB1 and CB2 receptors, with a CB2 affinity of 0.91nM and 13x selectivity over the CB1 receptor. In animal studies it has been found to be effective for the treatment of glioma, a form of brain tumor. A large number of related analogues are known where the 1,1-dimethylbenzyl group is substituted or replaced by other groups, with a fairly well established structure-activity relationship.".
- KM-233 atcPrefix "none".
- KM-233 casNumber "628263-22-9".
- KM-233 iupacName "(−)-(6aR,7,10,10aR)-tetrahydro-6,6,9-trimethyl-3-(1-methyl-1-phenylethyl)-6H-dibenzo[b,d]pyran-1-ol".
- KM-233 thumbnail KM-233_structure.png?width=300.
- KM-233 wikiPageID "36033185".
- KM-233 wikiPageLength "3975".
- KM-233 wikiPageOutDegree "15".
- KM-233 wikiPageRevisionID "624180345".
- KM-233 wikiPageWikiLink AM-411.
- KM-233 wikiPageWikiLink AMG-36.
- KM-233 wikiPageWikiLink Cannabinoid_receptor_1.
- KM-233 wikiPageWikiLink Cannabinoid_receptor_2.
- KM-233 wikiPageWikiLink Cannabinoid_receptor_type_1.
- KM-233 wikiPageWikiLink Cannabinoid_receptor_type_2.
- KM-233 wikiPageWikiLink Cannabis_(drug).
- KM-233 wikiPageWikiLink Category:Benzochromenes.
- KM-233 wikiPageWikiLink Category:Cannabinoids.
- KM-233 wikiPageWikiLink Category:Diterpenes.
- KM-233 wikiPageWikiLink Category:Phenols.
- KM-233 wikiPageWikiLink Glioma.
- KM-233 wikiPageWikiLink Isomer.
- KM-233 wikiPageWikiLink Pentyl.
- KM-233 wikiPageWikiLink Side_chain.
- KM-233 wikiPageWikiLink Structure-activity_relationship.
- KM-233 wikiPageWikiLink Structure–activity_relationship.
- KM-233 wikiPageWikiLink Tetrahydrocannabinol.
- KM-233 wikiPageWikiLinkText "KM-233".
- KM-233 atcPrefix "none".
- KM-233 c "25".
- KM-233 casNumber "628263".
- KM-233 chembl "119592".
- KM-233 chemspiderid "8423597".
- KM-233 drugName "KM-233".
- KM-233 h "30".
- KM-233 hasPhotoCollection KM-233.
- KM-233 inchi "1".
- KM-233 inchikey "GZYXCXRHVALIJD-WOJBJXKFBS".
- KM-233 iupacName "--tetrahydro-6,6,9-trimethyl-3--6H-dibenzo[b,d]pyran-1-ol".
- KM-233 legalStatus "?".
- KM-233 molecularWeight "362.503".
- KM-233 o "2".
- KM-233 smiles "CC1=CC[C@@H]2[C@@H]C3=CO".
- KM-233 stdinchi "1".
- KM-233 stdinchikey "GZYXCXRHVALIJD-WOJBJXKFSA-N".
- KM-233 wikiPageUsesTemplate Template:Cannabinoid-stub.
- KM-233 wikiPageUsesTemplate Template:Cannabinoids.
- KM-233 wikiPageUsesTemplate Template:Drugbox.
- KM-233 wikiPageUsesTemplate Template:Reflist.
- KM-233 subject Category:Benzochromenes.
- KM-233 subject Category:Cannabinoids.
- KM-233 subject Category:Diterpenes.
- KM-233 subject Category:Phenols.
- KM-233 hypernym Drug.
- KM-233 type Article.
- KM-233 type ChemicalSubstance.
- KM-233 type Drug.
- KM-233 type Alcohol.
- KM-233 type Article.
- KM-233 type Cannabinoid.
- KM-233 type Chemical.
- KM-233 type Diterpene.
- KM-233 type Drug.
- KM-233 type Heterocycle.
- KM-233 type Terpene.
- KM-233 type ChemicalObject.
- KM-233 type Thing.
- KM-233 type Q8386.
- KM-233 comment "KM-233 is a drug which is an analogue of Δ8-tetrahydrocannabinol (THC), the less active but more stable isomer of the active component of Cannabis. km-233 differs from Δ8-THC by the pentyl side chain being replaced by a 1,1-dimethylbenzyl group. It has high binding affinity in vitro for both the CB1 and CB2 receptors, with a CB2 affinity of 0.91nM and 13x selectivity over the CB1 receptor. In animal studies it has been found to be effective for the treatment of glioma, a form of brain tumor.".
- KM-233 label "KM-233".
- KM-233 sameAs m.0j_2ccb.
- KM-233 sameAs KM-233.
- KM-233 sameAs KM-233.
- KM-233 sameAs Q6333245.
- KM-233 sameAs Q6333245.
- KM-233 wasDerivedFrom KM-233?oldid=624180345.
- KM-233 depiction KM-233_structure.png.
- KM-233 isPrimaryTopicOf KM-233.
- KM-233 name "KM-233".