Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Janet_E._Mertz> ?p ?o }
- Janet_E._Mertz abstract "Janet E. Mertz (born 1949) is an American biochemist, molecular biologist, and cancer researcher. She is currently the Elizabeth McCoy Professor of Oncology in the McArdle Laboratory for Cancer Research at the University of Wisconsin – Madison. Mertz is best known for disproving Lawrence Summers’ 2005 suggestion that women lack the intrinsic aptitude to excel in mathematics at the highest level and for discovering an easy method for joining together DNAs from different species . This latter finding initiated the era of genetic engineering whose ramifications form the basis of modern genetics and the biotechnology industry.After completing bachelor degrees in biology and electrical engineering at the Massachusetts Institute of Technology, Mertz attended graduate school at Stanford University from 1970-1975, earning a Ph.D. in Biochemistry. While taking a course held at the Cold Spring Harbor Laboratory in summer 1971, she mentioned her plan to grow mutants of the oncovirus, SV40, by molecular cloning of them in the human gut bacterium, E. coli. This event led, initially, to a voluntary moratorium on cloning of viral oncogenes and, later on, the cloning of any DNA that might contain potentially biohazardous materials until theoretical safety concerns could be addressed and guidelines for their safe use could be developed and implementedIn the interim, in collaboration with Ronald W. Davis, Mertz discovered that DNA ends generated by cutting with the EcoRI restriction enzyme are “sticky”, permitting any two such DNAs to be readily “recombined”. Using this discovery, in June 1972 she easily created the first recombinant DNA that could have been cloned in bacteria . Her success with this project contributed to her thesis adviser, Paul Berg, receiving the 1980 Nobel Prize in Chemistry. However, Mertz did not proceed with this cloning because of the moratorium in place at that time, leaving it for Herbert Boyer, Stanley N. Cohen and their colleagues to prove in 1973 that recombinant DNAs made by this method can actually self-replicate in bacteria. Thus, most of Mertz’s Ph.D. thesis centered, instead, around developing other ways to create, select, and grow mutants of SV40 for studying this virus’ functions and so it could be used as the first eukaryotic cloning vector. The US Patent 4,237,224, Process for Producing Biologically Functional Molecular Chimeras”, which generated over $250 million in licensing and royalty income, listed only Boyer and Cohen as co-inventors . Some have questioned whether these patents were valid given the earlier publications by Peter Lobban and A. Dale Kaiser and the Berg laboratory that were already in the public domain at the time this application was filed in November 1974".
- Janet_E._Mertz academicAdvisor Harvey_Lodish.
- Janet_E._Mertz academicAdvisor John_Gurdon.
- Janet_E._Mertz almaMater Massachusetts_Institute_of_Technology.
- Janet_E._Mertz almaMater Stanford_University.
- Janet_E._Mertz birthDate "1949".
- Janet_E._Mertz birthPlace The_Bronx.
- Janet_E._Mertz birthYear "1949".
- Janet_E._Mertz doctoralAdvisor Paul_Berg.
- Janet_E._Mertz field Biochemistry.
- Janet_E._Mertz field Oncology.
- Janet_E._Mertz field Virology.
- Janet_E._Mertz knownFor Gender_&_Math.
- Janet_E._Mertz knownFor Recombinant_DNA.
- Janet_E._Mertz nationality United_States.
- Janet_E._Mertz wikiPageExternalLink citations?user=-FJ2X-cAAAAJ&hl=en&oi=sra.
- Janet_E._Mertz wikiPageID "47275926".
- Janet_E._Mertz wikiPageLength "10037".
- Janet_E._Mertz wikiPageOutDegree "68".
- Janet_E._Mertz wikiPageRevisionID "672242713".
- Janet_E._Mertz wikiPageWikiLink A._Dale_Kaiser.
- Janet_E._Mertz wikiPageWikiLink Bacteria.
- Janet_E._Mertz wikiPageWikiLink Bacterium.
- Janet_E._Mertz wikiPageWikiLink Biochemistry.
- Janet_E._Mertz wikiPageWikiLink Biotechnology.
- Janet_E._Mertz wikiPageWikiLink Breast_cancer.
- Janet_E._Mertz wikiPageWikiLink Cancer.
- Janet_E._Mertz wikiPageWikiLink Category:1949_births.
- Janet_E._Mertz wikiPageWikiLink Category:American_biochemists.
- Janet_E._Mertz wikiPageWikiLink Category:American_molecular_biologists.
- Janet_E._Mertz wikiPageWikiLink Category:Cancer_researchers.
- Janet_E._Mertz wikiPageWikiLink Category:Fellows_of_the_American_Association_for_the_Advancement_of_Science.
- Janet_E._Mertz wikiPageWikiLink Category:Living_people.
- Janet_E._Mertz wikiPageWikiLink Category:Massachusetts_Institute_of_Technology_alumni.
- Janet_E._Mertz wikiPageWikiLink Category:People_from_the_Bronx.
- Janet_E._Mertz wikiPageWikiLink Category:Stanford_University_alumni.
- Janet_E._Mertz wikiPageWikiLink Cloning_vector.
- Janet_E._Mertz wikiPageWikiLink Cold_Spring_Harbor_Laboratory.
- Janet_E._Mertz wikiPageWikiLink DNA.
- Janet_E._Mertz wikiPageWikiLink Doctor_of_Philosophy.
- Janet_E._Mertz wikiPageWikiLink E._coli.
- Janet_E._Mertz wikiPageWikiLink Edward_M._De_Robertis.
- Janet_E._Mertz wikiPageWikiLink Epstein-Barr_virus.
- Janet_E._Mertz wikiPageWikiLink Epstein–Barr_virus.
- Janet_E._Mertz wikiPageWikiLink Escherichia_coli.
- Janet_E._Mertz wikiPageWikiLink Estrogen_receptor.
- Janet_E._Mertz wikiPageWikiLink Eukaryote.
- Janet_E._Mertz wikiPageWikiLink Gender_&_Math.
- Janet_E._Mertz wikiPageWikiLink Gene.
- Janet_E._Mertz wikiPageWikiLink Genetic_engineering.
- Janet_E._Mertz wikiPageWikiLink Genetics.
- Janet_E._Mertz wikiPageWikiLink Harvey_Lodish.
- Janet_E._Mertz wikiPageWikiLink Hepatitis_B_virus.
- Janet_E._Mertz wikiPageWikiLink Herbert_Boyer.
- Janet_E._Mertz wikiPageWikiLink John_B._Gurdon.
- Janet_E._Mertz wikiPageWikiLink John_Gurdon.
- Janet_E._Mertz wikiPageWikiLink Lawrence_Summers.
- Janet_E._Mertz wikiPageWikiLink Macromolecule.
- Janet_E._Mertz wikiPageWikiLink Massachusetts_Institute_of_Technology.
- Janet_E._Mertz wikiPageWikiLink Mathematics.
- Janet_E._Mertz wikiPageWikiLink Medical_Research_Council_(United_Kingdom).
- Janet_E._Mertz wikiPageWikiLink Molecular_cloning.
- Janet_E._Mertz wikiPageWikiLink Mutant.
- Janet_E._Mertz wikiPageWikiLink Nobel_Prize_in_Chemistry.
- Janet_E._Mertz wikiPageWikiLink Nuclear_receptor.
- Janet_E._Mertz wikiPageWikiLink Oncogene.
- Janet_E._Mertz wikiPageWikiLink Oncology.
- Janet_E._Mertz wikiPageWikiLink Oncovirus.
- Janet_E._Mertz wikiPageWikiLink Oocyte.
- Janet_E._Mertz wikiPageWikiLink Patent.
- Janet_E._Mertz wikiPageWikiLink Paul_Berg.
- Janet_E._Mertz wikiPageWikiLink Ph.D..
- Janet_E._Mertz wikiPageWikiLink Postdoctoral_researcher.
- Janet_E._Mertz wikiPageWikiLink Public_domain.
- Janet_E._Mertz wikiPageWikiLink Recombinant_DNA.
- Janet_E._Mertz wikiPageWikiLink Restriction_enzyme.
- Janet_E._Mertz wikiPageWikiLink Ronald_W._Davis.
- Janet_E._Mertz wikiPageWikiLink SV40.
- Janet_E._Mertz wikiPageWikiLink Self-replicate.
- Janet_E._Mertz wikiPageWikiLink Self-replication.
- Janet_E._Mertz wikiPageWikiLink Species.
- Janet_E._Mertz wikiPageWikiLink Stanford_University.
- Janet_E._Mertz wikiPageWikiLink Stanley_N._Cohen.
- Janet_E._Mertz wikiPageWikiLink Stanley_Norman_Cohen.
- Janet_E._Mertz wikiPageWikiLink The_Bronx.
- Janet_E._Mertz wikiPageWikiLink The_Bronx,_New_York.
- Janet_E._Mertz wikiPageWikiLink United_States.
- Janet_E._Mertz wikiPageWikiLink University_of_Wisconsin,_Madison.
- Janet_E._Mertz wikiPageWikiLink University_of_Wisconsin_–_Madison.
- Janet_E._Mertz wikiPageWikiLink University_of_Wisconsin–Madison.
- Janet_E._Mertz wikiPageWikiLink Virology.
- Janet_E._Mertz academicAdvisors Harvey_Lodish.
- Janet_E._Mertz academicAdvisors John_B._Gurdon.
- Janet_E._Mertz academicAdvisors John_Gurdon.
- Janet_E._Mertz almaMater Massachusetts_Institute_of_Technology.
- Janet_E._Mertz almaMater Stanford_University.
- Janet_E._Mertz birthDate "1949".
- Janet_E._Mertz birthPlace The_Bronx.
- Janet_E._Mertz birthPlace The_Bronx,_New_York.
- Janet_E._Mertz dateOfBirth "1949".