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- JWH-019 abstract "JWH-019 is an analgesic chemical from the naphthoylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is the N1-hexyl homologue of the more common synthetic cannabinoid compound JWH-018. Unlike the butyl homologue JWH-073, which is several times weaker than JWH-018, the hexyl homologue is only slightly less potent, although extending the chain one carbon longer to the heptyl homologue JWH-020 results in dramatic loss of activity. These results show that the optimum side chain length for CB1 binding in the naphthoylindole series is the five-carbon pentyl chain, shorter than in the classical cannabinoids where a seven-carbon heptyl chain produces the most potent compounds. This difference is thought to reflect a slightly different binding conformation adopted by the naphthoylindole compounds as compared to the classical cannabinoids, and may be useful in characterising the active site of the CB1 and CB2 receptors.".
- JWH-019 casNumber "209414-08-4".
- JWH-019 iupacName "1-hexyl-3-(naphthalen-1-oyl)indole".
- JWH-019 thumbnail JWH019.svg?width=300.
- JWH-019 wikiPageID "28402539".
- JWH-019 wikiPageLength "4972".
- JWH-019 wikiPageOutDegree "21".
- JWH-019 wikiPageRevisionID "683540279".
- JWH-019 wikiPageWikiLink Alkane.
- JWH-019 wikiPageWikiLink Alkyl.
- JWH-019 wikiPageWikiLink Analgesic.
- JWH-019 wikiPageWikiLink Butyl.
- JWH-019 wikiPageWikiLink Cannabinoid.
- JWH-019 wikiPageWikiLink Category:Designer_drugs.
- JWH-019 wikiPageWikiLink Category:JWH_cannabinoids.
- JWH-019 wikiPageWikiLink Category:Naphthoylindoles.
- JWH-019 wikiPageWikiLink Classical_cannabinoids.
- JWH-019 wikiPageWikiLink Heptyl.
- JWH-019 wikiPageWikiLink Hexyl.
- JWH-019 wikiPageWikiLink Homolog_(chemistry).
- JWH-019 wikiPageWikiLink Homology_(chemistry).
- JWH-019 wikiPageWikiLink JWH-007.
- JWH-019 wikiPageWikiLink JWH-018.
- JWH-019 wikiPageWikiLink JWH-020.
- JWH-019 wikiPageWikiLink JWH-073.
- JWH-019 wikiPageWikiLink JWH-200.
- JWH-019 wikiPageWikiLink List_of_JWH_cannabinoids.
- JWH-019 wikiPageWikiLink Naphthoylindole.
- JWH-019 wikiPageWikiLink Pentyl.
- JWH-019 wikiPageWikiLink State_of_Virginia.
- JWH-019 wikiPageWikiLink Virginia.
- JWH-019 wikiPageWikiLinkText "JWH-019".
- JWH-019 c "25".
- JWH-019 casNumber "209414".
- JWH-019 chemspiderid "24598813".
- JWH-019 h "25".
- JWH-019 hasPhotoCollection JWH-019.
- JWH-019 inchi "1".
- JWH-019 inchikey "PALJPGHWDUHUPO-UHFFFAOYAV".
- JWH-019 iupacName "1".
- JWH-019 legalStatus "Class B , illegal in Sweden, I-N".
- JWH-019 molecularWeight "355.471".
- JWH-019 n "1".
- JWH-019 o "1".
- JWH-019 smiles "c3cccc2c3cccc2Cc1cnc4c1cccc4".
- JWH-019 stdinchi "1".
- JWH-019 stdinchikey "PALJPGHWDUHUPO-UHFFFAOYSA-N".
- JWH-019 verifiedrevid "451563324".
- JWH-019 wikiPageUsesTemplate Template:Cannabinoid-stub.
- JWH-019 wikiPageUsesTemplate Template:Cannabinoids.
- JWH-019 wikiPageUsesTemplate Template:Drugbox.
- JWH-019 wikiPageUsesTemplate Template:Reflist.
- JWH-019 subject Category:Designer_drugs.
- JWH-019 subject Category:JWH_cannabinoids.
- JWH-019 subject Category:Naphthoylindoles.
- JWH-019 hypernym Chemical.
- JWH-019 type Article.
- JWH-019 type ChemicalCompound.
- JWH-019 type ChemicalSubstance.
- JWH-019 type Drug.
- JWH-019 type Article.
- JWH-019 type Cannabinoid.
- JWH-019 type Chemical.
- JWH-019 type Drug.
- JWH-019 type Ketone.
- JWH-019 type ChemicalObject.
- JWH-019 type Thing.
- JWH-019 type Q8386.
- JWH-019 comment "JWH-019 is an analgesic chemical from the naphthoylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is the N1-hexyl homologue of the more common synthetic cannabinoid compound JWH-018. Unlike the butyl homologue JWH-073, which is several times weaker than JWH-018, the hexyl homologue is only slightly less potent, although extending the chain one carbon longer to the heptyl homologue JWH-020 results in dramatic loss of activity.".
- JWH-019 label "JWH-019".
- JWH-019 sameAs JWH-019.
- JWH-019 sameAs JWH-019.
- JWH-019 sameAs m.0crdk8s.
- JWH-019 sameAs JWH-019.
- JWH-019 sameAs JWH-019.
- JWH-019 sameAs JWH-019.
- JWH-019 sameAs Q423592.
- JWH-019 sameAs Q423592.
- JWH-019 wasDerivedFrom JWH-019?oldid=683540279.
- JWH-019 depiction JWH019.svg.
- JWH-019 isPrimaryTopicOf JWH-019.