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- Intrinsic_termination abstract "Intrinsic termination (also called Rho-independent termination) is a mechanism in prokaryotes that causes RNA transcription to be stopped. In this mechanism, the mRNA contains a sequence that can base pair with itself to form a stem-loop structure 7-20 base pairs in length that is also rich in cytosine-guanine base pairs. C-G base pairs have significant base-stacking interactions (especially repeated G-C pairs) and can form three hydrogen bonds between each other, resulting in a stable RNA duplex. Following the stem-loop structure is a chain of uracil residues. The bonds between uracil and adenine are very weak. A protein bound to RNA polymerase (nusA) binds to the stem-loop structure tightly enough to cause the polymerase to temporarily stall. This pausing of the polymerase coincides with transcription of the poly-uracil sequence. The weak Adenine-Uracil bonds lower the energy of destabilization for the RNA-DNA duplex, allowing it to unwind and dissociate from the RNA polymerase.Stem-loop structures that are not followed by a poly-Uracil sequence cause the RNA polymerase to pause, but it will typically continue transcription after a brief time because the duplex is too stable to unwind far enough to cause termination.Rho-independent transcription termination is a frequent mechanism underlying the activity of cis-acting RNA regulatory elements, such as riboswitches.".
- Intrinsic_termination thumbnail Rho-independent_terminator_sequence_and_secondary_structure_conservation.jpg?width=300.
- Intrinsic_termination wikiPageID "12279693".
- Intrinsic_termination wikiPageLength "2777".
- Intrinsic_termination wikiPageOutDegree "15".
- Intrinsic_termination wikiPageRevisionID "656668322".
- Intrinsic_termination wikiPageWikiLink Adenine.
- Intrinsic_termination wikiPageWikiLink Category:Gene_expression.
- Intrinsic_termination wikiPageWikiLink Category:Molecular_biology.
- Intrinsic_termination wikiPageWikiLink Cytosine.
- Intrinsic_termination wikiPageWikiLink File:Rho-independent_terminator_sequence_and_secondary_structure_conservation.jpg.
- Intrinsic_termination wikiPageWikiLink Guanine.
- Intrinsic_termination wikiPageWikiLink Prokaryote.
- Intrinsic_termination wikiPageWikiLink Prokaryotes.
- Intrinsic_termination wikiPageWikiLink RNA.
- Intrinsic_termination wikiPageWikiLink Rho_factor.
- Intrinsic_termination wikiPageWikiLink Riboswitch.
- Intrinsic_termination wikiPageWikiLink Stem-loop.
- Intrinsic_termination wikiPageWikiLink Transcription_(genetics).
- Intrinsic_termination wikiPageWikiLink Trp_operon.
- Intrinsic_termination wikiPageWikiLink Uracil.
- Intrinsic_termination wikiPageWikiLink WebGeSTer.
- Intrinsic_termination wikiPageWikiLinkText "Intrinsic termination".
- Intrinsic_termination wikiPageWikiLinkText "Intrinsic transcription terminators".
- Intrinsic_termination wikiPageWikiLinkText "Rho-independent terminator".
- Intrinsic_termination wikiPageWikiLinkText "Rho-independent transcription terminator".
- Intrinsic_termination wikiPageWikiLinkText "intrinsic termination".
- Intrinsic_termination wikiPageWikiLinkText "intrinsic terminator".
- Intrinsic_termination wikiPageWikiLinkText "intrinsic transcription termination".
- Intrinsic_termination wikiPageWikiLinkText "intrinsic transcription terminators".
- Intrinsic_termination wikiPageWikiLinkText "rho independent terminator".
- Intrinsic_termination wikiPageWikiLinkText "rho-independent transcription termination".
- Intrinsic_termination wikiPageWikiLinkText "rho-independent transcription terminator".
- Intrinsic_termination wikiPageWikiLinkText "rho-independent transcription terminators".
- Intrinsic_termination wikiPageWikiLinkText "stem loop terminator structure".
- Intrinsic_termination wikiPageWikiLinkText "terminator hairpin".
- Intrinsic_termination wikiPageWikiLinkText "terminator stem".
- Intrinsic_termination wikiPageWikiLinkText "transcription terminator".
- Intrinsic_termination wikiPageWikiLinkText "transcription terminators".
- Intrinsic_termination hasPhotoCollection Intrinsic_termination.
- Intrinsic_termination wikiPageUsesTemplate Template:Reflist.
- Intrinsic_termination wikiPageUsesTemplate Template:Transcription.
- Intrinsic_termination subject Category:Gene_expression.
- Intrinsic_termination subject Category:Molecular_biology.
- Intrinsic_termination hypernym Mechanism.
- Intrinsic_termination type Organisation.
- Intrinsic_termination type Process.
- Intrinsic_termination comment "Intrinsic termination (also called Rho-independent termination) is a mechanism in prokaryotes that causes RNA transcription to be stopped. In this mechanism, the mRNA contains a sequence that can base pair with itself to form a stem-loop structure 7-20 base pairs in length that is also rich in cytosine-guanine base pairs.".
- Intrinsic_termination label "Intrinsic termination".
- Intrinsic_termination sameAs m.02vyrgm.
- Intrinsic_termination sameAs Ро-независимая_терминация.
- Intrinsic_termination sameAs Q6058731.
- Intrinsic_termination sameAs Q6058731.
- Intrinsic_termination wasDerivedFrom Intrinsic_termination?oldid=656668322.
- Intrinsic_termination depiction Rho-independent_terminator_sequence_and_secondary_structure_conservation.jpg.
- Intrinsic_termination isPrimaryTopicOf Intrinsic_termination.