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- Intermediate-density_lipoprotein abstract "Intermediate-density lipoproteins (IDLs) belong to the lipoprotein particle family and are formed from the degradation of very low-density lipoproteins. IDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) that enable fats and cholesterol to move within the water-based solution of the bloodstream. Each native IDL particle consists of protein that encircles various fatty acids, enabling, as a water-soluble particle, these fatty acids to travel in the aqueous blood environment as part of the fat transport system within the body. Their size is, in general, 25 to 35 nm in diameter, and they contain primarily a range of triacylglycerols and cholesterol esters. They are cleared from the plasma into the liver by receptor-mediated endocytosis, or further degraded to form LDL particles.(Although one might intuitively assume that "intermediate-density" refers to a density between that of high-density and low-density lipoproteins, it in fact refers to a density between that of low-density and very-low-density lipoproteins. Lipoproteins are classified as less dense when the fat to protein ratio is increased.)In general, IDL, somewhat similar to low-density lipoprotein (LDL), transports a variety of triglyceride fats and cholesterol and, like LDL, can also promote the growth of atheroma.VLDL is a large, triglyceride-rich lipoprotein secreted by the liver that transports triglyceride to adipose tissue and muscle. The triglycerides in VLDL are removed in capillaries by the enzyme lipoprotein lipase, and the VLDL returns to the circulation as a smaller particle with a new name, intermediate-density lipoprotein (IDL). The IDL particles have lost most of their triglyceride, but they retain cholesteryl esters. Some of the IDL particles are rapidly taken up by the liver; others remain in circulation, where they undergo further triglyceride hydrolysis and are converted to LDL. A distinguishing feature of the IDL particle is their content of multiple copies of the receptor ligand ApoE in addition to a single copy of ApoB-100. The multiple copies of ApoE allow IDL to bind to the LDL receptor with a very high affinity. When IDL is converted to LDL, the ApoE leaves the particle and only the ApoB-100 remains. Thereafter, the affinity for the LDL receptor is much reduced.[1]".
- Intermediate-density_lipoprotein wikiPageID "844841".
- Intermediate-density_lipoprotein wikiPageLength "2680".
- Intermediate-density_lipoprotein wikiPageOutDegree "21".
- Intermediate-density_lipoprotein wikiPageRevisionID "618415994".
- Intermediate-density_lipoprotein wikiPageWikiLink Atheroma.
- Intermediate-density_lipoprotein wikiPageWikiLink Blood.
- Intermediate-density_lipoprotein wikiPageWikiLink Blood_plasma.
- Intermediate-density_lipoprotein wikiPageWikiLink Category:Lipoproteins.
- Intermediate-density_lipoprotein wikiPageWikiLink Cholesterol.
- Intermediate-density_lipoprotein wikiPageWikiLink Cholesteryl_ester.
- Intermediate-density_lipoprotein wikiPageWikiLink Cholesteryl_esters.
- Intermediate-density_lipoprotein wikiPageWikiLink Chylomicron.
- Intermediate-density_lipoprotein wikiPageWikiLink Chylomicrons.
- Intermediate-density_lipoprotein wikiPageWikiLink Ester.
- Intermediate-density_lipoprotein wikiPageWikiLink High-density_lipoprotein.
- Intermediate-density_lipoprotein wikiPageWikiLink LDL.
- Intermediate-density_lipoprotein wikiPageWikiLink LDL_receptor.
- Intermediate-density_lipoprotein wikiPageWikiLink Lipoprotein.
- Intermediate-density_lipoprotein wikiPageWikiLink Lipoprotein_lipase.
- Intermediate-density_lipoprotein wikiPageWikiLink Liver.
- Intermediate-density_lipoprotein wikiPageWikiLink Low-density_lipoprotein.
- Intermediate-density_lipoprotein wikiPageWikiLink Receptor-mediated_endocytosis.
- Intermediate-density_lipoprotein wikiPageWikiLink Triacylglycerol.
- Intermediate-density_lipoprotein wikiPageWikiLink Triglyceride.
- Intermediate-density_lipoprotein wikiPageWikiLink VLDL.
- Intermediate-density_lipoprotein wikiPageWikiLink Very_low-density_lipoprotein.
- Intermediate-density_lipoprotein wikiPageWikiLinkText "IDL".
- Intermediate-density_lipoprotein wikiPageWikiLinkText "Intermediate-density lipoprotein".
- Intermediate-density_lipoprotein wikiPageWikiLinkText "intermediate-density lipoprotein".
- Intermediate-density_lipoprotein wikiPageWikiLinkText "intermediate-density lipoproteins".
- Intermediate-density_lipoprotein hasPhotoCollection Intermediate-density_lipoprotein.
- Intermediate-density_lipoprotein wikiPageUsesTemplate Template:Lipoproteins.
- Intermediate-density_lipoprotein subject Category:Lipoproteins.
- Intermediate-density_lipoprotein type Lipid.
- Intermediate-density_lipoprotein type Lipid.
- Intermediate-density_lipoprotein type Lipoprotein.
- Intermediate-density_lipoprotein comment "Intermediate-density lipoproteins (IDLs) belong to the lipoprotein particle family and are formed from the degradation of very low-density lipoproteins. IDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) that enable fats and cholesterol to move within the water-based solution of the bloodstream.".
- Intermediate-density_lipoprotein label "Intermediate-density lipoprotein".
- Intermediate-density_lipoprotein sameAs Lipoproteïnes_de_densitat_intermèdia.
- Intermediate-density_lipoprotein sameAs Lipoproteína_de_densidad_intermedia.
- Intermediate-density_lipoprotein sameAs Lipoprotéine_de_densité_intermédiaire.
- Intermediate-density_lipoprotein sameAs Lipoproteína_de_densidade_intermedia.
- Intermediate-density_lipoprotein sameAs Lipoproteine_a_densità_intermedia.
- Intermediate-density_lipoprotein sameAs IDL_(medycyna).
- Intermediate-density_lipoprotein sameAs m.03gfwy.
- Intermediate-density_lipoprotein sameAs Липопротеины_промежуточной_плотности.
- Intermediate-density_lipoprotein sameAs Intermediate-density_lipoprotein.
- Intermediate-density_lipoprotein sameAs Ara_yoğunluklu_lipoprotein.
- Intermediate-density_lipoprotein sameAs Q2619230.
- Intermediate-density_lipoprotein sameAs Q2619230.
- Intermediate-density_lipoprotein wasDerivedFrom Intermediate-density_lipoprotein?oldid=618415994.
- Intermediate-density_lipoprotein isPrimaryTopicOf Intermediate-density_lipoprotein.