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- Insert_Therapeutics abstract "Insert Therapeutics, Inc., now Calando Pharmaceuticals, Inc., is a medical research company that uses nanobiotechnology specializing in therapeutic agents that are conjugated, to facilitate and enhance drug delivery. The small company was founded in 2000, is located in Pasadena, California, and majority-owned by Arrowhead Research Corporation.The conjugates consist of a cyclodextrin-containing polymer (Cyclosert) that acts as a drug delivery system, and a linked medication, such as a chemotherapeutic drug of already proven efficacy. The size of the polymer is designed to “fit” the specific target, as vessels in a neoplasm allow for leakage of different size of polymers, as in healthy tissue. The leaked conjugates are concentrated in the target area. As a result chemotherapeutic activity is locally enhanced, while general side effects are decreased.At least one of their conjugates, IT-101, has been investigated in a clinical trial at City of Hope National Medical Center.".
- Insert_Therapeutics wikiPageExternalLink www.calandopharma.com.
- Insert_Therapeutics wikiPageExternalLink www.ceruleanrx.com.
- Insert_Therapeutics wikiPageID "15081677".
- Insert_Therapeutics wikiPageLength "1433".
- Insert_Therapeutics wikiPageOutDegree "11".
- Insert_Therapeutics wikiPageRevisionID "610599656".
- Insert_Therapeutics wikiPageWikiLink Arrowhead_Research_Corporation.
- Insert_Therapeutics wikiPageWikiLink Biotransformation.
- Insert_Therapeutics wikiPageWikiLink CRLX101.
- Insert_Therapeutics wikiPageWikiLink Category:Biotechnology.
- Insert_Therapeutics wikiPageWikiLink City_of_Hope_National_Medical_Center.
- Insert_Therapeutics wikiPageWikiLink Clinical_trial.
- Insert_Therapeutics wikiPageWikiLink Conjugation_(biochemistry).
- Insert_Therapeutics wikiPageWikiLink Cyclodextrin.
- Insert_Therapeutics wikiPageWikiLink Drug_delivery.
- Insert_Therapeutics wikiPageWikiLink IT-101.
- Insert_Therapeutics wikiPageWikiLink Medical_research.
- Insert_Therapeutics wikiPageWikiLink Nanobiotechnology.
- Insert_Therapeutics wikiPageWikiLink Pasadena,_California.
- Insert_Therapeutics wikiPageWikiLinkText "Insert Therapeutics".
- Insert_Therapeutics hasPhotoCollection Insert_Therapeutics.
- Insert_Therapeutics wikiPageUsesTemplate Template:Reflist.
- Insert_Therapeutics subject Category:Biotechnology.
- Insert_Therapeutics comment "Insert Therapeutics, Inc., now Calando Pharmaceuticals, Inc., is a medical research company that uses nanobiotechnology specializing in therapeutic agents that are conjugated, to facilitate and enhance drug delivery.".
- Insert_Therapeutics label "Insert Therapeutics".
- Insert_Therapeutics sameAs إدراج_علم_التداوي.
- Insert_Therapeutics sameAs m.03hgwvv.
- Insert_Therapeutics sameAs Q6037384.
- Insert_Therapeutics sameAs Q6037384.
- Insert_Therapeutics wasDerivedFrom Insert_Therapeutics?oldid=610599656.
- Insert_Therapeutics isPrimaryTopicOf Insert_Therapeutics.