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- ImmunoGen abstract "ImmunoGen, Inc. (NASDAQ: IMGN) is a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen was founded in 1981 and is headquartered in Waltham, Massachusetts.An ImmunoGen ADC contains a manufactured antibody that binds to a target found on cancer cells, with one of the company's potent cell-killing agents attached as a "payload". The antibody serves to deliver the cell-killing agent specifically to cancer cells bearing its target and the payload serves to kill these cells. In some cases, the antibody also has anticancer activity.ImmunoGen uses its ADC technology to develop its own product candidates. These include IMGN853, IMGN529, IMGN289, and IMGN779. It also selectively outlicenses limited use of its technology to other companies. Companies licensing ImmunoGen's technology include Amgen, Bayer HealthCare, Biotest, Genentech/Roche, Lilly, Novartis, Sanofi, and Takeda. Roche's Kadcyla (ado-trastuzumab emtansine) utilizes ImmunoGen's ADC technology. It has been approved and launched in a number of countries, including the US, where it is marketed by Genentech, a member of the Roche Group.The ADCs currently in the clinic with ImmunoGen technology all employ one of the company's maytansinoid cell-killing agents, either DM1 or DM4. DM1 attached to an antibody with ImmunoGen's thioether linker is called "emtansine" in its International Nonproprietary Name name (e.g., ado-trastuzumab emtansine). DM1 attached to an antibody with ImmunoGen's SPP linker is called "mertansine" (e.g., lorvotuzumab mertansine). DM4 attached with ImmunoGen's SPDB linker is called "ravtansine" (e.g., indatuximab ravtansine, anetumab ravtansine(BAY94-9343)), and DM4 attached with ImmunoGen's sSPDB linker is called "soravtansine".".
- ImmunoGen foundingYear "1981".
- ImmunoGen locationCity Waltham,_Massachusetts.
- ImmunoGen locationCountry United_States.
- ImmunoGen numberOfEmployees "280".
- ImmunoGen type Public_company.
- ImmunoGen wikiPageExternalLink www.immunogen.com.
- ImmunoGen wikiPageID "42153115".
- ImmunoGen wikiPageLength "2795".
- ImmunoGen wikiPageOutDegree "14".
- ImmunoGen wikiPageRevisionID "680700932".
- ImmunoGen wikiPageWikiLink Anetumab_ravtansine.
- ImmunoGen wikiPageWikiLink Antibody-drug_conjugate.
- ImmunoGen wikiPageWikiLink Category:Companies_established_in_1981.
- ImmunoGen wikiPageWikiLink Category:Publicly_traded_companies_of_the_United_States.
- ImmunoGen wikiPageWikiLink Emtansine.
- ImmunoGen wikiPageWikiLink Indatuximab_ravtansine.
- ImmunoGen wikiPageWikiLink International_Nonproprietary_Name.
- ImmunoGen wikiPageWikiLink Lorvotuzumab_mertansine.
- ImmunoGen wikiPageWikiLink Mertansine.
- ImmunoGen wikiPageWikiLink Public_company.
- ImmunoGen wikiPageWikiLink Soravtansine.
- ImmunoGen wikiPageWikiLink United_States.
- ImmunoGen wikiPageWikiLink Waltham,_Massachusetts.
- ImmunoGen wikiPageWikiLinkText "ImmunoGen Inc".
- ImmunoGen wikiPageWikiLinkText "ImmunoGen".
- ImmunoGen date "April 2015".
- ImmunoGen foundation "1981".
- ImmunoGen hasPhotoCollection ImmunoGen.
- ImmunoGen industry "healthcare".
- ImmunoGen locationCity Waltham,_Massachusetts.
- ImmunoGen locationCountry United_States.
- ImmunoGen name "ImmunoGen Inc.".
- ImmunoGen numEmployees "280".
- ImmunoGen reason "Not formatted and/or laid out correctly".
- ImmunoGen type Public_company.
- ImmunoGen wikiPageUsesTemplate Template:Biotech-stub.
- ImmunoGen wikiPageUsesTemplate Template:Cleanup.
- ImmunoGen wikiPageUsesTemplate Template:Infobox_company.
- ImmunoGen wikiPageUsesTemplate Template:NASDAQ.
- ImmunoGen wikiPageUsesTemplate Template:Reflist.
- ImmunoGen subject Category:Companies_established_in_1981.
- ImmunoGen subject Category:Publicly_traded_companies_of_the_United_States.
- ImmunoGen type Agent.
- ImmunoGen type Company.
- ImmunoGen type Organisation.
- ImmunoGen type Organization.
- ImmunoGen type Agent.
- ImmunoGen type SocialPerson.
- ImmunoGen type Thing.
- ImmunoGen type Q43229.
- ImmunoGen comment "ImmunoGen, Inc. (NASDAQ: IMGN) is a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen was founded in 1981 and is headquartered in Waltham, Massachusetts.An ImmunoGen ADC contains a manufactured antibody that binds to a target found on cancer cells, with one of the company's potent cell-killing agents attached as a "payload".".
- ImmunoGen label "ImmunoGen".
- ImmunoGen sameAs m.03p2d4d.
- ImmunoGen sameAs Q15964806.
- ImmunoGen sameAs Q15964806.
- ImmunoGen wasDerivedFrom ImmunoGen?oldid=680700932.
- ImmunoGen homepage www.immunogen.com.
- ImmunoGen isPrimaryTopicOf ImmunoGen.
- ImmunoGen name "ImmunoGen Inc.".