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- Immortal_DNA_strand_hypothesis abstract "The immortal DNA strand hypothesis was proposed in 1975 by John Cairns as a mechanism for adult stem cells to minimize mutations in their genomes. This hypothesis proposes that instead of segregating their DNA during mitosis in a random manner, adult stem cells divide their DNA asymmetrically, and retain a distinct template set of DNA strands (parental strands) in each division. By retaining the same set of template DNA strands, adult stem cells would pass mutations arising from errors in DNA replication on to non-stem cell daughters that soon terminally differentiate (end mitotic divisions and become a functional cell). Passing on these replication errors would allow adult stem cells to reduce their rate of accumulation of mutations that could lead to serious genetic disorders such as cancer.Although evidence for this mechanism exists, whether it is a mechanism acting in adult stem cells in vivo is still controversial.".
- Immortal_DNA_strand_hypothesis wikiPageExternalLink 1045b.
- Immortal_DNA_strand_hypothesis wikiPageExternalLink 46.
- Immortal_DNA_strand_hypothesis wikiPageExternalLink 1045c.
- Immortal_DNA_strand_hypothesis wikiPageID "7188879".
- Immortal_DNA_strand_hypothesis wikiPageLength "13785".
- Immortal_DNA_strand_hypothesis wikiPageOutDegree "27".
- Immortal_DNA_strand_hypothesis wikiPageRevisionID "594122396".
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Adult_stem_cell.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Adult_stem_cells.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Assay.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Bromodeoxyuridine.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Cancer.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Category:Cell_biology.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Category:DNA.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Category:Developmental_biology.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Category:Stem_cells.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Cellular_differentiation.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink DNA.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink DNA_replication.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Emmanuel_David_Tannenbaum.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Genetic_disorder.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Genome.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Genomes.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Homeostasis.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink In_vivo.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink John_Cairns_(biochemist).
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Mitosis.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Mitotic.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Mutation.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Mutations.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Myosatellite_cell.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink P53.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Point_mutation.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink S_phase.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Satellite_cells.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Skeletal_muscle.
- Immortal_DNA_strand_hypothesis wikiPageWikiLink Thymidine.
- Immortal_DNA_strand_hypothesis wikiPageWikiLinkText "Immortal DNA strand hypothesis".
- Immortal_DNA_strand_hypothesis wikiPageWikiLinkText "immortal DNA strand hypothesis".
- Immortal_DNA_strand_hypothesis wikiPageWikiLinkText "immortal strand hypothesis".
- Immortal_DNA_strand_hypothesis hasPhotoCollection Immortal_DNA_strand_hypothesis.
- Immortal_DNA_strand_hypothesis subject Category:Cell_biology.
- Immortal_DNA_strand_hypothesis subject Category:DNA.
- Immortal_DNA_strand_hypothesis subject Category:Developmental_biology.
- Immortal_DNA_strand_hypothesis subject Category:Stem_cells.
- Immortal_DNA_strand_hypothesis comment "The immortal DNA strand hypothesis was proposed in 1975 by John Cairns as a mechanism for adult stem cells to minimize mutations in their genomes. This hypothesis proposes that instead of segregating their DNA during mitosis in a random manner, adult stem cells divide their DNA asymmetrically, and retain a distinct template set of DNA strands (parental strands) in each division.".
- Immortal_DNA_strand_hypothesis label "Immortal DNA strand hypothesis".
- Immortal_DNA_strand_hypothesis sameAs Thxc3xa9orie_de_lADN_immortel.
- Immortal_DNA_strand_hypothesis sameAs תאוריית_הגדיל_הנצחי.
- Immortal_DNA_strand_hypothesis sameAs m.025vkvn.
- Immortal_DNA_strand_hypothesis sameAs Q2892307.
- Immortal_DNA_strand_hypothesis sameAs Q2892307.
- Immortal_DNA_strand_hypothesis wasDerivedFrom Immortal_DNA_strand_hypothesis?oldid=594122396.
- Immortal_DNA_strand_hypothesis isPrimaryTopicOf Immortal_DNA_strand_hypothesis.