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- Illudin abstract "The illudins are a family of sesquiterpenes with antitumor antibiotic properties produced by some mushrooms. In their isolated form, illudins show selective toxicity for myelocytic leukemia and other carcinoma cells.Illudin is highly toxic, with little apparent therapeutic value in its natural form. It is thought responsible for the ill effects caused by various Omphalotus species like O. olearius and O. illudens (Jack 'o' Lantern mushrooms), and O. nidiformis (Australian ghost fungus).Inside cells, illudin is chemically changed to react with DNA, thus creating an unknown type of DNA damage that blocks the transcription process. This block can only be relieved by the DNA repair system nucleotide excision repair. Damages in non-transcribed DNA areas are ignored. This property was exploited by the company MGI Pharma to develop an illudin-derivative called Irofulven for use as an anti-cancer medicine. Its application is still in the experimental phase.".
- Illudin thumbnail Illudin_family.svg?width=300.
- Illudin wikiPageID "2586142".
- Illudin wikiPageLength "1852".
- Illudin wikiPageOutDegree "20".
- Illudin wikiPageRevisionID "679820957".
- Illudin wikiPageWikiLink Antibiotic.
- Illudin wikiPageWikiLink Antibiotics.
- Illudin wikiPageWikiLink Carcinoma.
- Illudin wikiPageWikiLink Category:Alcohols.
- Illudin wikiPageWikiLink Category:Cyclopropanes.
- Illudin wikiPageWikiLink Category:Experimental_cancer_drugs.
- Illudin wikiPageWikiLink Category:Indanes.
- Illudin wikiPageWikiLink Category:Ketones.
- Illudin wikiPageWikiLink Category:Spiro_compounds.
- Illudin wikiPageWikiLink Category:Terpenes_and_terpenoids.
- Illudin wikiPageWikiLink Irofulven.
- Illudin wikiPageWikiLink Leukemia.
- Illudin wikiPageWikiLink Mushroom.
- Illudin wikiPageWikiLink Nucleotide_excision_repair.
- Illudin wikiPageWikiLink Omphalotus.
- Illudin wikiPageWikiLink Omphalotus_illudens.
- Illudin wikiPageWikiLink Omphalotus_nidiformis.
- Illudin wikiPageWikiLink Omphalotus_olearius.
- Illudin wikiPageWikiLink Sesquiterpene.
- Illudin wikiPageWikiLink Transcription_(genetics).
- Illudin wikiPageWikiLink File:Illudin_family.svg.
- Illudin wikiPageWikiLinkText "Illudin".
- Illudin wikiPageWikiLinkText "illudin".
- Illudin hasPhotoCollection Illudin.
- Illudin wikiPageUsesTemplate Template:Antineoplastic-drug-stub.
- Illudin wikiPageUsesTemplate Template:Cleanup-rewrite.
- Illudin wikiPageUsesTemplate Template:Reflist.
- Illudin subject Category:Alcohols.
- Illudin subject Category:Cyclopropanes.
- Illudin subject Category:Experimental_cancer_drugs.
- Illudin subject Category:Indanes.
- Illudin subject Category:Ketones.
- Illudin subject Category:Spiro_compounds.
- Illudin subject Category:Terpenes_and_terpenoids.
- Illudin hypernym Family.
- Illudin type Alcohol.
- Illudin type Sesquiterpene.
- Illudin type Terpene.
- Illudin comment "The illudins are a family of sesquiterpenes with antitumor antibiotic properties produced by some mushrooms. In their isolated form, illudins show selective toxicity for myelocytic leukemia and other carcinoma cells.Illudin is highly toxic, with little apparent therapeutic value in its natural form. It is thought responsible for the ill effects caused by various Omphalotus species like O. olearius and O. illudens (Jack 'o' Lantern mushrooms), and O.".
- Illudin label "Illudin".
- Illudin sameAs イルジン.
- Illudin sameAs m.07pvkw.
- Illudin sameAs Q17111935.
- Illudin sameAs Q17111935.
- Illudin wasDerivedFrom Illudin?oldid=679820957.
- Illudin depiction Illudin_family.svg.
- Illudin isPrimaryTopicOf Illudin.