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- INCENP abstract "Inner centromere protein is a protein that in humans is encoded by the INCENP gene.In mammalian cells, two broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger' (or transiently interacting) proteins. The constitutive proteins include CENPA (centromere protein A), CENPB, CENPC1, and CENPD.The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE; MCAK; KID; cytoplasmic dynein (e.g., DYNC1H1); CliPs (e.g. CLIP1); and CENPF/mitosin (CENPF). The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis.INCENP is a regulatory protein in the chromosome passenger complex. It is involved in regulation of the catalytic protein Aurora B. It performs this function in association with two other proteins - Survivin and Borealin. These proteins form a tight three-helical bundle. The N-terminal domain of INCENP is the domain involved in formation of this three-helical bundle.".
- INCENP entrezgene "3619".
- INCENP symbol "INCENP_ARK-bind".
- INCENP symbol "INCENP_N".
- INCENP wikiPageID "14766680".
- INCENP wikiPageLength "13606".
- INCENP wikiPageOutDegree "39".
- INCENP wikiPageRevisionID "678925556".
- INCENP wikiPageWikiLink Aurora_B.
- INCENP wikiPageWikiLink Aurora_B_kinase.
- INCENP wikiPageWikiLink CDCA8.
- INCENP wikiPageWikiLink CENPA.
- INCENP wikiPageWikiLink CENPC1.
- INCENP wikiPageWikiLink CENPF.
- INCENP wikiPageWikiLink CLIP1.
- INCENP wikiPageWikiLink Catalysis.
- INCENP wikiPageWikiLink Catalytic.
- INCENP wikiPageWikiLink Category:Protein_families.
- INCENP wikiPageWikiLink Cell_cycle.
- INCENP wikiPageWikiLink Centromere.
- INCENP wikiPageWikiLink Centromere_protein_B.
- INCENP wikiPageWikiLink Centromere_protein_E.
- INCENP wikiPageWikiLink Chromosome.
- INCENP wikiPageWikiLink Chromosome_segregation.
- INCENP wikiPageWikiLink Cytokinesis.
- INCENP wikiPageWikiLink DYNC1H1.
- INCENP wikiPageWikiLink Gene.
- INCENP wikiPageWikiLink H2AFZ.
- INCENP wikiPageWikiLink KIF22.
- INCENP wikiPageWikiLink KIF2C.
- INCENP wikiPageWikiLink Kinase.
- INCENP wikiPageWikiLink Midbody_(cell_biology).
- INCENP wikiPageWikiLink Mitosis.
- INCENP wikiPageWikiLink Multiprotein_complex.
- INCENP wikiPageWikiLink N-terminal.
- INCENP wikiPageWikiLink N-terminus.
- INCENP wikiPageWikiLink Protein.
- INCENP wikiPageWikiLink Protein-protein_interaction.
- INCENP wikiPageWikiLink Protein_complex.
- INCENP wikiPageWikiLink Protein_domain.
- INCENP wikiPageWikiLink Proteins.
- INCENP wikiPageWikiLink Protein–protein_interaction.
- INCENP wikiPageWikiLink RCC1.
- INCENP wikiPageWikiLink Survivin.
- INCENP wikiPageWikiLink Telophase.
- INCENP wikiPageWikiLink Yeast.
- INCENP wikiPageWikiLinkText "INCENP".
- INCENP caption "crystal structure of a survivin-borealin-incenp core complex".
- INCENP caption "crystal structure of aurora b kinase in complex with a aminothiazole inhibitor".
- INCENP hasPhotoCollection INCENP.
- INCENP interpro "IPR005635".
- INCENP interpro "IPR022006".
- INCENP name "Chromosome passenger complex protein INCENP N terminal".
- INCENP name "Inner centromere protein, ARK binding region".
- INCENP pfam "PF03941".
- INCENP pfam "PF12178".
- INCENP requireManualInspection "no".
- INCENP symbol "INCENP_ARK-bind".
- INCENP symbol "INCENP_N".
- INCENP updateCitations "yes".
- INCENP updatePage "yes".
- INCENP updateProteinBox "yes".
- INCENP updateSummary "no".
- INCENP wikiPageUsesTemplate Template:Gene-11-stub.
- INCENP wikiPageUsesTemplate Template:Infobox_protein_family.
- INCENP wikiPageUsesTemplate Template:InterPro_content.
- INCENP wikiPageUsesTemplate Template:PBB.
- INCENP wikiPageUsesTemplate Template:PBB_Controls.
- INCENP wikiPageUsesTemplate Template:PBB_Further_reading.
- INCENP wikiPageUsesTemplate Template:Refbegin.
- INCENP wikiPageUsesTemplate Template:Refend.
- INCENP wikiPageUsesTemplate Template:Reflist.
- INCENP subject Category:Protein_families.
- INCENP hypernym Protein.
- INCENP type Biomolecule.
- INCENP type Protein.
- INCENP type Thing.
- INCENP type Q206229.
- INCENP type Q8054.
- INCENP comment "Inner centromere protein is a protein that in humans is encoded by the INCENP gene.In mammalian cells, two broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger' (or transiently interacting) proteins.".
- INCENP label "INCENP".
- INCENP sameAs m.03gx8sd.
- INCENP sameAs INCENP.
- INCENP sameAs Q15996692.
- INCENP sameAs Q15996692.
- INCENP wasDerivedFrom INCENP?oldid=678925556.
- INCENP isPrimaryTopicOf INCENP.