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- Host-pathogen_interface abstract "In cellular biology, the host-pathogen interface refers to the exchange of biochemical signals that occurs when a microbe encounters its host or target cell. Such cross-talk between the two can result in either a symbiotic or hostile cross-fire. In certain locations, such as the gastro-intestinal tract, the animal host's intestinal mucous-lining on the host-cell external surface may prevent a food-poisoning pathogen from achieving physical adhesion to the plasma membrane of the host cell. In addition, the arsenal of anti-microbial peptides and defensins secreted by the host can damage the integrity of the approaching microbial pathogens. Innate and cellular immunity of the animal host may also neutralize the pathogens before they come in close contact with specific host or target cells. Gram-negative bacterial pathogens having an additional outer membrane consisting largely of endotoxic lipopolysaccharide (LPS), membrane-pore forming porins, and some other outer membrane proteins, providing an apparent advantage compared to Gram-positive microbes, which lack outer membrane. Thus Gram-negative organisms have an additional storage compartment called a periplasm, a cellular space between bacterial outer membrane and the inner membrane. The periplasm allows special attributes to the Gram negative organisms, as this compartment can expand to accommodate increasing amounts of microbial secretions; it can also bleb out nanovesicles, called bacterial outer membrane vesicles, (OMVs). These OMVs can translocate a variety of biochemical signal molecules to other target cells of its own type (intra-species) for quorum sensing or other competing microbes (inter-species) to thwart them from sharing the same nutritional niche, or to animal/plant eukaryotic cells for inter-kingdom interactions. OMVs thus open a new vista in the important field of membrane vesicle trafficking. This was heralded as a revolutionary process of vesicular exocytosis in prokaryotes for multiple purposes, including invasion of animal hosts, and inter-bacterial interactions.".
- Host-pathogen_interface wikiPageID "42335006".
- Host-pathogen_interface wikiPageLength "11487".
- Host-pathogen_interface wikiPageOutDegree "31".
- Host-pathogen_interface wikiPageRevisionID "673152546".
- Host-pathogen_interface wikiPageWikiLink Actin.
- Host-pathogen_interface wikiPageWikiLink Apoptosis.
- Host-pathogen_interface wikiPageWikiLink Atopy.
- Host-pathogen_interface wikiPageWikiLink Bacterial_outer_membrane_vesicles.
- Host-pathogen_interface wikiPageWikiLink Bleb_(cell_biology).
- Host-pathogen_interface wikiPageWikiLink Category:Biological_interactions.
- Host-pathogen_interface wikiPageWikiLink Cell_biology.
- Host-pathogen_interface wikiPageWikiLink Cellular_biology.
- Host-pathogen_interface wikiPageWikiLink Cytoskeleton.
- Host-pathogen_interface wikiPageWikiLink Cytosol.
- Host-pathogen_interface wikiPageWikiLink Defensin.
- Host-pathogen_interface wikiPageWikiLink E3_ubiquitin_ligase.
- Host-pathogen_interface wikiPageWikiLink Endotoxic.
- Host-pathogen_interface wikiPageWikiLink Eukaryote.
- Host-pathogen_interface wikiPageWikiLink Exocytosis.
- Host-pathogen_interface wikiPageWikiLink Gastro-intestinal_tract.
- Host-pathogen_interface wikiPageWikiLink Gram-negative.
- Host-pathogen_interface wikiPageWikiLink Gram-negative_bacteria.
- Host-pathogen_interface wikiPageWikiLink Gram-positive.
- Host-pathogen_interface wikiPageWikiLink Gram-positive_bacteria.
- Host-pathogen_interface wikiPageWikiLink Host–pathogen_interaction.
- Host-pathogen_interface wikiPageWikiLink Human_gastrointestinal_tract.
- Host-pathogen_interface wikiPageWikiLink Lipopolysaccharide.
- Host-pathogen_interface wikiPageWikiLink Macrophage.
- Host-pathogen_interface wikiPageWikiLink Membrane_vesicle_trafficking.
- Host-pathogen_interface wikiPageWikiLink Periplasm.
- Host-pathogen_interface wikiPageWikiLink Porin_(protein).
- Host-pathogen_interface wikiPageWikiLink Prokaryote.
- Host-pathogen_interface wikiPageWikiLink Prokaryotes.
- Host-pathogen_interface wikiPageWikiLink Salmonella.
- Host-pathogen_interface wikiPageWikiLink Symbiosis.
- Host-pathogen_interface wikiPageWikiLink Symbiotic.
- Host-pathogen_interface wikiPageWikiLink Type_III_secretion.
- Host-pathogen_interface wikiPageWikiLink Type_three_secretion_system.
- Host-pathogen_interface wikiPageWikiLink Ubiquitin_ligase.
- Host-pathogen_interface wikiPageWikiLinkText "Host-pathogen interface".
- Host-pathogen_interface wikiPageWikiLinkText "host-pathogen interface".
- Host-pathogen_interface hasPhotoCollection Host-pathogen_interface.
- Host-pathogen_interface wikiPageUsesTemplate Template:Context.
- Host-pathogen_interface wikiPageUsesTemplate Template:Reflist.
- Host-pathogen_interface wikiPageUsesTemplate Template:Wide_image.
- Host-pathogen_interface subject Category:Biological_interactions.
- Host-pathogen_interface comment "In cellular biology, the host-pathogen interface refers to the exchange of biochemical signals that occurs when a microbe encounters its host or target cell. Such cross-talk between the two can result in either a symbiotic or hostile cross-fire. In certain locations, such as the gastro-intestinal tract, the animal host's intestinal mucous-lining on the host-cell external surface may prevent a food-poisoning pathogen from achieving physical adhesion to the plasma membrane of the host cell.".
- Host-pathogen_interface label "Host-pathogen interface".
- Host-pathogen_interface sameAs m.01028hhw.
- Host-pathogen_interface sameAs Q17027635.
- Host-pathogen_interface sameAs Q17027635.
- Host-pathogen_interface wasDerivedFrom Host-pathogen_interface?oldid=673152546.
- Host-pathogen_interface isPrimaryTopicOf Host-pathogen_interface.