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- Histotoxic_hypoxia abstract "Histotoxic hypoxia (also called histoxic hypoxia) is the inability of cells to take up or utilize oxygen from the bloodstream, despite physiologically normal delivery of oxygen to such cells and tissues. Histotoxic hypoxia results from tissue poisoning, such as that caused by cyanide (which acts by inhibiting cytochrome oxidase), and certain other poisons like hydrogen sulfide (byproduct of sewage and used in leather tanning).Histotoxic hypoxia refers to a reduction in ATP production by the mitochondria due to a defect in the cellular usage of oxygen. An example of histotoxic hypoxia is cyanide poisoning. There is a profound drop in tissue oxygen consumption since the reaction of oxygen with cytochrome c oxidase is blocked by the presence of cyanide. There are other chemicals that interrupt the mitochondrial electron transport chain (e.g., rotenone, antimycin A) and produce effects on tissue oxygenation similar to that of cyanide. Oxygen extraction decreases in parallel with the lower oxygen consumption, with a resulting increase in venous oxygen content and PvO2. Although cyanide stimulates the peripheral respiratory chemoreceptors, increasing the inspired oxygen fraction is not helpful, since there is already an adequate amount of oxygen which the poisoned cells cannot use.".
- Histotoxic_hypoxia wikiPageID "2100665".
- Histotoxic_hypoxia wikiPageLength "1898".
- Histotoxic_hypoxia wikiPageOutDegree "8".
- Histotoxic_hypoxia wikiPageRevisionID "681574453".
- Histotoxic_hypoxia wikiPageWikiLink Category:Poisoning_by_drugs,_medicaments_and_biological_substances.
- Histotoxic_hypoxia wikiPageWikiLink Category:Respiration.
- Histotoxic_hypoxia wikiPageWikiLink Cyanide.
- Histotoxic_hypoxia wikiPageWikiLink Cyanide_poisoning.
- Histotoxic_hypoxia wikiPageWikiLink Cytochrome_c_oxidase.
- Histotoxic_hypoxia wikiPageWikiLink Cytochrome_oxidase.
- Histotoxic_hypoxia wikiPageWikiLink Hydrogen_sulfide.
- Histotoxic_hypoxia wikiPageWikiLink Hypoxia_(medical).
- Histotoxic_hypoxia wikiPageWikiLink Poison.
- Histotoxic_hypoxia wikiPageWikiLinkText "Histotoxic hypoxia".
- Histotoxic_hypoxia wikiPageWikiLinkText "histotoxic hypoxia".
- Histotoxic_hypoxia hasPhotoCollection Histotoxic_hypoxia.
- Histotoxic_hypoxia wikiPageUsesTemplate Template:Disease-stub.
- Histotoxic_hypoxia wikiPageUsesTemplate Template:Reflist.
- Histotoxic_hypoxia subject Category:Poisoning_by_drugs,_medicaments_and_biological_substances.
- Histotoxic_hypoxia subject Category:Respiration.
- Histotoxic_hypoxia type Article.
- Histotoxic_hypoxia type Disease.
- Histotoxic_hypoxia type Article.
- Histotoxic_hypoxia type Element.
- Histotoxic_hypoxia type Thing.
- Histotoxic_hypoxia type Q12136.
- Histotoxic_hypoxia comment "Histotoxic hypoxia (also called histoxic hypoxia) is the inability of cells to take up or utilize oxygen from the bloodstream, despite physiologically normal delivery of oxygen to such cells and tissues.".
- Histotoxic_hypoxia label "Histotoxic hypoxia".
- Histotoxic_hypoxia sameAs m.06m51x.
- Histotoxic_hypoxia sameAs Гістотоксин.
- Histotoxic_hypoxia sameAs Q12099245.
- Histotoxic_hypoxia sameAs Q12099245.
- Histotoxic_hypoxia wasDerivedFrom Histotoxic_hypoxia?oldid=681574453.
- Histotoxic_hypoxia isPrimaryTopicOf Histotoxic_hypoxia.