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- Histone-modifying_enzymes abstract "The packaging of the eukaryotic genome into highly condensed chromatin makes it inaccessible to the factors required for gene transcription, DNA replication, recombination and repair. Eukaryotes have developed intricate mechanisms to overcome this repressive barrier imposed by the chromatin. The nucleosome is composed of an octamer of the four core histones (H3, H4, H2A, H2B) around which 147 base pairs of DNA are wrapped. Several distinct classes of enzyme can modify histones at multiple sites. The figure on the right enlists those histone-modifying enzymes whose specificity has been determined. There are at least eight distinct types of modifications found on histones (see the legend box on the top left of the figure). Enzymes have been identified for acetylation,methylation, demethylation, phosphorylation,ubiquitination, sumoylation,ADP-ribosylation,deimination, and proline isomerization. For a detailed example of histone modifications in transcription regulation see RNA polymerase control by chromatin structure and table Influence of modifications on gene expression in mammalian cells.".
- Histone-modifying_enzymes thumbnail NucleosomeKG.jpg?width=300.
- Histone-modifying_enzymes wikiPageID "12139474".
- Histone-modifying_enzymes wikiPageLength "5569".
- Histone-modifying_enzymes wikiPageOutDegree "33".
- Histone-modifying_enzymes wikiPageRevisionID "680659490".
- Histone-modifying_enzymes wikiPageWikiLink ADP-ribosylation.
- Histone-modifying_enzymes wikiPageWikiLink Acetylation.
- Histone-modifying_enzymes wikiPageWikiLink Category:Epigenetics.
- Histone-modifying_enzymes wikiPageWikiLink Category:Genetics.
- Histone-modifying_enzymes wikiPageWikiLink Category:Proteins.
- Histone-modifying_enzymes wikiPageWikiLink Chromatin.
- Histone-modifying_enzymes wikiPageWikiLink Citrullination.
- Histone-modifying_enzymes wikiPageWikiLink Deimination.
- Histone-modifying_enzymes wikiPageWikiLink Demethylation.
- Histone-modifying_enzymes wikiPageWikiLink Enzyme.
- Histone-modifying_enzymes wikiPageWikiLink Eukaryote.
- Histone-modifying_enzymes wikiPageWikiLink Eukaryotes.
- Histone-modifying_enzymes wikiPageWikiLink Eukaryotic.
- Histone-modifying_enzymes wikiPageWikiLink Genetic_recombination.
- Histone-modifying_enzymes wikiPageWikiLink Genome.
- Histone-modifying_enzymes wikiPageWikiLink Histone.
- Histone-modifying_enzymes wikiPageWikiLink Histone_acetyltransferase.
- Histone-modifying_enzymes wikiPageWikiLink Histone_deacetylase.
- Histone-modifying_enzymes wikiPageWikiLink Histone_methyltransferase.
- Histone-modifying_enzymes wikiPageWikiLink Histones.
- Histone-modifying_enzymes wikiPageWikiLink Methylation.
- Histone-modifying_enzymes wikiPageWikiLink Nucleosome.
- Histone-modifying_enzymes wikiPageWikiLink PRMT4_pathway.
- Histone-modifying_enzymes wikiPageWikiLink Phosphorylation.
- Histone-modifying_enzymes wikiPageWikiLink Proline_isomerization.
- Histone-modifying_enzymes wikiPageWikiLink RNA_polymerase_II.
- Histone-modifying_enzymes wikiPageWikiLink RNA_polymerase_control_by_chromatin_structure.
- Histone-modifying_enzymes wikiPageWikiLink SUMO_protein.
- Histone-modifying_enzymes wikiPageWikiLink Sumoylation.
- Histone-modifying_enzymes wikiPageWikiLink Transcription_(genetics).
- Histone-modifying_enzymes wikiPageWikiLink Ubiquitin.
- Histone-modifying_enzymes wikiPageWikiLink Ubiquitination.
- Histone-modifying_enzymes wikiPageWikiLink File:NucleosomeKG.jpg.
- Histone-modifying_enzymes wikiPageWikiLinkText "Histone-modifying enzymes".
- Histone-modifying_enzymes hasPhotoCollection Histone-modifying_enzymes.
- Histone-modifying_enzymes wikiPageUsesTemplate Template:Reflist.
- Histone-modifying_enzymes subject Category:Epigenetics.
- Histone-modifying_enzymes subject Category:Genetics.
- Histone-modifying_enzymes subject Category:Proteins.
- Histone-modifying_enzymes type Biomolecule.
- Histone-modifying_enzymes type Biomolecule.
- Histone-modifying_enzymes type Epigenetic.
- Histone-modifying_enzymes type Nutrient.
- Histone-modifying_enzymes comment "The packaging of the eukaryotic genome into highly condensed chromatin makes it inaccessible to the factors required for gene transcription, DNA replication, recombination and repair. Eukaryotes have developed intricate mechanisms to overcome this repressive barrier imposed by the chromatin. The nucleosome is composed of an octamer of the four core histones (H3, H4, H2A, H2B) around which 147 base pairs of DNA are wrapped.".
- Histone-modifying_enzymes label "Histone-modifying enzymes".
- Histone-modifying_enzymes sameAs Enzimas_modificadoras_de_histonas.
- Histone-modifying_enzymes sameAs m.02vr3x0.
- Histone-modifying_enzymes sameAs Histonmodifierande_enzym.
- Histone-modifying_enzymes sameAs Q5773144.
- Histone-modifying_enzymes sameAs Q5773144.
- Histone-modifying_enzymes wasDerivedFrom Histone-modifying_enzymes?oldid=680659490.
- Histone-modifying_enzymes depiction NucleosomeKG.jpg.
- Histone-modifying_enzymes isPrimaryTopicOf Histone-modifying_enzymes.