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- Hepatitis_delta_virus_ribozyme abstract "The hepatitis delta virus (HDV) ribozyme is a non-coding RNA found in the hepatitis delta virus that is necessary for viral replication and is thought to be the only catalytic RNA known to be required for viability of a human pathogen. The ribozyme acts to process the RNA transcripts to unit lengths in a self-cleavage reaction. The ribozyme is found to be active in vivo in the absence of any protein factors and is the fastest known naturally occurring self-cleaving RNA.The crystal structure of this ribozyme has been solved using X-ray crystallography and shows five helical segments connected by a double pseudoknot.In addition to the sense (genomic version), all HDV viruses also have an anti-genomic version of the HDV ribozyme. This version is not the exact complementary sequence but adopts the same structure as the sense (genomic) strand. The only "significant" differences between the two are a small bulge in P4 stem and a shorter J4/2 junction.The hepatitis delta virus ribozyme is structurally and biochemically related to the Mammalian CPEB3 ribozyme. Unrelated sequences with high similarity to the HDV ribozyme have evolved through convergent evolution in some retrotransposons (e.g. in the R2 RNA element in insects and in the L1Tc and probably other retrotransposons in trypanosomatids).".
- Hepatitis_delta_virus_ribozyme thumbnail RF00094.jpg?width=300.
- Hepatitis_delta_virus_ribozyme wikiPageExternalLink species.cgi?fkLongueur=2.
- Hepatitis_delta_virus_ribozyme wikiPageID "11420921".
- Hepatitis_delta_virus_ribozyme wikiPageLength "16825".
- Hepatitis_delta_virus_ribozyme wikiPageOutDegree "22".
- Hepatitis_delta_virus_ribozyme wikiPageRevisionID "678911879".
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Acid_catalysis.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Biomolecular_structure.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Category:Non-coding_RNA.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Category:RNA_splicing.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Category:Ribozymes.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Conserved_sequence.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Convergent_evolution.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Gene.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Hairpin_ribozyme.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Hepatitis_D.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Hepatitis_delta_virus.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Mammalian_CPEB3_ribozyme.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Non-coding_RNA.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Pathogen.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Pseudoknot.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink R2_RNA_element.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Retrotransposon.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Retrotransposons.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Ribozyme.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Secondary_structure.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Sequence_conservation.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink Virus.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink X-ray_crystallography.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink File:Acid_Base_Catalysis.png.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLink File:PDB_1cx0_EBI.jpg.
- Hepatitis_delta_virus_ribozyme wikiPageWikiLinkText "HDV ribozyme".
- Hepatitis_delta_virus_ribozyme wikiPageWikiLinkText "Hepatitis Delta Virus (HDV) ribozyme".
- Hepatitis_delta_virus_ribozyme wikiPageWikiLinkText "Hepatitis delta virus ribozyme".
- Hepatitis_delta_virus_ribozyme wikiPageWikiLinkText "hepatitis delta virus ribozyme".
- Hepatitis_delta_virus_ribozyme wikiPageWikiLinkText "hepatitis delta virus".
- Hepatitis_delta_virus_ribozyme caption "Predicted secondary structure and sequence conservation of HDV ribozyme".
- Hepatitis_delta_virus_ribozyme hasPhotoCollection Hepatitis_delta_virus_ribozyme.
- Hepatitis_delta_virus_ribozyme id "RF00094".
- Hepatitis_delta_virus_ribozyme name "Hepatitis delta virus ribozyme".
- Hepatitis_delta_virus_ribozyme rfam "RF00094".
- Hepatitis_delta_virus_ribozyme rnaType Gene.
- Hepatitis_delta_virus_ribozyme rnaType Ribozyme.
- Hepatitis_delta_virus_ribozyme symbol "HDV_ribozyme".
- Hepatitis_delta_virus_ribozyme taxDomain "Viruses".
- Hepatitis_delta_virus_ribozyme wikiPageUsesTemplate Template:Infobox_rfam.
- Hepatitis_delta_virus_ribozyme wikiPageUsesTemplate Template:Reflist.
- Hepatitis_delta_virus_ribozyme wikiPageUsesTemplate Template:Rfam.
- Hepatitis_delta_virus_ribozyme subject Category:Non-coding_RNA.
- Hepatitis_delta_virus_ribozyme subject Category:RNA_splicing.
- Hepatitis_delta_virus_ribozyme subject Category:Ribozymes.
- Hepatitis_delta_virus_ribozyme hypernym RNA.
- Hepatitis_delta_virus_ribozyme type Protein.
- Hepatitis_delta_virus_ribozyme comment "The hepatitis delta virus (HDV) ribozyme is a non-coding RNA found in the hepatitis delta virus that is necessary for viral replication and is thought to be the only catalytic RNA known to be required for viability of a human pathogen. The ribozyme acts to process the RNA transcripts to unit lengths in a self-cleavage reaction.".
- Hepatitis_delta_virus_ribozyme label "Hepatitis delta virus ribozyme".
- Hepatitis_delta_virus_ribozyme sameAs m.02rby9q.
- Hepatitis_delta_virus_ribozyme sameAs Q5731738.
- Hepatitis_delta_virus_ribozyme sameAs Q5731738.
- Hepatitis_delta_virus_ribozyme wasDerivedFrom Hepatitis_delta_virus_ribozyme?oldid=678911879.
- Hepatitis_delta_virus_ribozyme depiction RF00094.jpg.
- Hepatitis_delta_virus_ribozyme isPrimaryTopicOf Hepatitis_delta_virus_ribozyme.