Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/HUS1> ?p ?o }
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- HUS1 abstract "Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event.".
- HUS1 entrezgene "3364".
- HUS1 wikiPageID "14179524".
- HUS1 wikiPageLength "14944".
- HUS1 wikiPageOutDegree "8".
- HUS1 wikiPageRevisionID "673283364".
- HUS1 wikiPageWikiLink Gene.
- HUS1 wikiPageWikiLink HDAC1.
- HUS1 wikiPageWikiLink PCNA.
- HUS1 wikiPageWikiLink Proliferating_cell_nuclear_antigen.
- HUS1 wikiPageWikiLink Protein.
- HUS1 wikiPageWikiLink Protein-protein_interaction.
- HUS1 wikiPageWikiLink Protein–protein_interaction.
- HUS1 wikiPageWikiLink RAD17.
- HUS1 wikiPageWikiLink RAD1_homolog.
- HUS1 wikiPageWikiLink RAD9A.
- HUS1 wikiPageWikiLinkText "HUS1".
- HUS1 hasPhotoCollection HUS1.
- HUS1 requireManualInspection "no".
- HUS1 summaryText "The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C , which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event.".
- HUS1 updateCitations "yes".
- HUS1 updatePage "yes".
- HUS1 updateProteinBox "yes".
- HUS1 updateSummary "yes".
- HUS1 wikiPageUsesTemplate Template:Gene-7-stub.
- HUS1 wikiPageUsesTemplate Template:PBB.
- HUS1 wikiPageUsesTemplate Template:PBB_Controls.
- HUS1 wikiPageUsesTemplate Template:PBB_Further_reading.
- HUS1 wikiPageUsesTemplate Template:PBB_Summary.
- HUS1 wikiPageUsesTemplate Template:Refbegin.
- HUS1 wikiPageUsesTemplate Template:Refend.
- HUS1 wikiPageUsesTemplate Template:Reflist.
- HUS1 hypernym Protein.
- HUS1 type Biomolecule.
- HUS1 type Protein.
- HUS1 type Thing.
- HUS1 type Q206229.
- HUS1 type Q8054.
- HUS1 comment "Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1.".
- HUS1 label "HUS1".
- HUS1 sameAs HUS1.
- HUS1 sameAs m.03cx1dw.
- HUS1 sameAs HUS1.
- HUS1 sameAs Q5636190.
- HUS1 sameAs Q5636190.
- HUS1 wasDerivedFrom HUS1?oldid=673283364.
- HUS1 isPrimaryTopicOf HUS1.