Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/HSD17B4> ?p ?o }
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- HSD17B4 abstract "Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene.The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation. It was first identified as a 17-beta-estradiol dehydrogenase (Leenders et al., 1996; van Grunsven et al., 1998). Peroxisomal beta-oxidation of fatty acids, originally described by Lazarow and de Duve (1976), is catalyzed by 3 enzymes: acyl-CoA oxidase (see, e.g., ACOX1, MIM 609751); the 'D-bifunctional enzyme,' with enoyl-CoA-hydratase and D-3-hydroxyacyl-CoA dehydrogenase activity, and 3-ketoacyl-CoA thiolase (MIM 604054). See also the L-bifunctional peroxisomal protein (EHHADH; MIM 607037). The D- and L-bifunctional proteins have different substrate specificities. The D-bifunctional protein catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids and also acts in shortening cholesterol for bile acid formation. In contrast, the L-specific bifunctional protein does not have the latter 2 activities (Jiang et al., 1997).[supplied by OMIM]".
- HSD17B4 entrezgene "3295".
- HSD17B4 wikiPageID "14759997".
- HSD17B4 wikiPageLength "9096".
- HSD17B4 wikiPageOutDegree "9".
- HSD17B4 wikiPageRevisionID "678851015".
- HSD17B4 wikiPageWikiLink 3-ketoacyl-CoA_thiolase.
- HSD17B4 wikiPageWikiLink ACOX1.
- HSD17B4 wikiPageWikiLink Acyl-CoA_oxidase.
- HSD17B4 wikiPageWikiLink D-3-hydroxyacyl-CoA_dehydrogenase.
- HSD17B4 wikiPageWikiLink D-bifunctional_protein_deficiency.
- HSD17B4 wikiPageWikiLink EHHADH.
- HSD17B4 wikiPageWikiLink Enoyl-CoA-hydratase.
- HSD17B4 wikiPageWikiLink Gene.
- HSD17B4 wikiPageWikiLink Protein.
- HSD17B4 wikiPageWikiLink Thiolase.
- HSD17B4 wikiPageWikiLinkText "HSD17B4".
- HSD17B4 hasPhotoCollection HSD17B4.
- HSD17B4 requireManualInspection "no".
- HSD17B4 summaryText "The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation. It was first identified as a 17-beta-estradiol dehydrogenase . Peroxisomal beta-oxidation of fatty acids, originally described by Lazarow and de Duve , is catalyzed by 3 enzymes: acyl-CoA oxidase ; the 'D-bifunctional enzyme,' with enoyl-CoA-hydratase and D-3-hydroxyacyl-CoA dehydrogenase activity, and 3-ketoacyl-CoA thiolase . See also the L-bifunctional peroxisomal protein . The D- and L-bifunctional proteins have different substrate specificities. The D-bifunctional protein catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids and also acts in shortening cholesterol for bile acid formation. In contrast, the L-specific bifunctional protein does not have the latter 2 activities .[supplied by OMIM]".
- HSD17B4 updateCitations "yes".
- HSD17B4 updatePage "yes".
- HSD17B4 updateProteinBox "yes".
- HSD17B4 updateSummary "yes".
- HSD17B4 wikiPageUsesTemplate Template:Gene-5-stub.
- HSD17B4 wikiPageUsesTemplate Template:PBB.
- HSD17B4 wikiPageUsesTemplate Template:PBB_Controls.
- HSD17B4 wikiPageUsesTemplate Template:PBB_Further_reading.
- HSD17B4 wikiPageUsesTemplate Template:PBB_Summary.
- HSD17B4 wikiPageUsesTemplate Template:PDB_Gallery.
- HSD17B4 wikiPageUsesTemplate Template:Peroxisomal_metabolism_enzymes.
- HSD17B4 wikiPageUsesTemplate Template:Refbegin.
- HSD17B4 wikiPageUsesTemplate Template:Refend.
- HSD17B4 wikiPageUsesTemplate Template:Reflist.
- HSD17B4 hypernym Protein.
- HSD17B4 type Biomolecule.
- HSD17B4 type Protein.
- HSD17B4 type Thing.
- HSD17B4 type Q206229.
- HSD17B4 type Q8054.
- HSD17B4 comment "Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene.The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation. It was first identified as a 17-beta-estradiol dehydrogenase (Leenders et al., 1996; van Grunsven et al., 1998).".
- HSD17B4 label "HSD17B4".
- HSD17B4 sameAs m.03gw_wn.
- HSD17B4 sameAs Q5635942.
- HSD17B4 sameAs Q5635942.
- HSD17B4 wasDerivedFrom HSD17B4?oldid=678851015.
- HSD17B4 isPrimaryTopicOf HSD17B4.