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- HLA-B15 abstract "HLA-B15 (B15) is an HLA-B serotype. The serotype identifies the B*15 gene-allele protein products of HLA-B.B15 is a broad antigen can be subdivided into several split antigens that are often used in characterization. These are B62, B63, B70, B71, B72, B75, B76, B77. B*15 is the largest allele grouping for any known human autosomal locus, idenitified as of August 2008 there are more than 150 alleles and ~140 amino acid sequence variants from those gene products. Some of these alleles are discussed below. Other alleles, such as B*46 evolved from B*15. One reason for the diversity of this group is that B15 is among a group of alleles enriched in the original humans that left Africa and dispersed across East Asia and Australia. As people traveled east the frequency of many alleles dropped or disappeared from migrants. However B*15 persisted, expanded and diversified. The wide range and complex environment selected for new alleles and promoted their expansion. B*46 for example is not found in Africa, and appears to have evolved and spread in East Asia, to several 100 million bearers worldwide.HLA-B15 allele *1502 is associated with the severe skin conditions Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) caused by carbamazepine drug sensitivity in East Asians.".
- HLA-B15 thumbnail HLA_B%5E1501.png?width=300.
- HLA-B15 wikiPageExternalLink getmap.cgi?chromosome=6p21.31.
- HLA-B15 wikiPageID "18735734".
- HLA-B15 wikiPageLength "7856".
- HLA-B15 wikiPageOutDegree "51".
- HLA-B15 wikiPageRevisionID "678849716".
- HLA-B15 wikiPageWikiLink Allele.
- HLA-B15 wikiPageWikiLink Amino_acid.
- HLA-B15 wikiPageWikiLink Carbamazepine.
- HLA-B15 wikiPageWikiLink Category:Drug-sensitivity_genes.
- HLA-B15 wikiPageWikiLink Category:HLA-B_alleles.
- HLA-B15 wikiPageWikiLink Chromosome_6_(human).
- HLA-B15 wikiPageWikiLink European_Bioinformatics_Institute.
- HLA-B15 wikiPageWikiLink HLA-B.
- HLA-B15 wikiPageWikiLink HLA-B46.
- HLA-B15 wikiPageWikiLink HLA-B62.
- HLA-B15 wikiPageWikiLink HLA-B63.
- HLA-B15 wikiPageWikiLink HLA-B70.
- HLA-B15 wikiPageWikiLink HLA-B75.
- HLA-B15 wikiPageWikiLink HLA-B77.
- HLA-B15 wikiPageWikiLink HLA_Informatics_Group.
- HLA-B15 wikiPageWikiLink History_and_naming_of_human_leukocyte_antigens.
- HLA-B15 wikiPageWikiLink Human_leukocyte_antigen.
- HLA-B15 wikiPageWikiLink Locus_(genetics).
- HLA-B15 wikiPageWikiLink Serotype.
- HLA-B15 wikiPageWikiLink Stevens–Johnson_syndrome.
- HLA-B15 wikiPageWikiLink Toxic_epidermal_necrolysis.
- HLA-B15 wikiPageWikiLink Wikt:broad_antigen.
- HLA-B15 wikiPageWikiLink Wikt:split_antigen.
- HLA-B15 wikiPageWikiLink File:HLA_B%5E1501.png.
- HLA-B15 wikiPageWikiLinkText "B*1501".
- HLA-B15 wikiPageWikiLinkText "B15".
- HLA-B15 wikiPageWikiLinkText "HLA-B15".
- HLA-B15 hasPhotoCollection HLA-B15.
- HLA-B15 wikiPageUsesTemplate Template:Clear.
- HLA-B15 wikiPageUsesTemplate Template:Further2.
- HLA-B15 wikiPageUsesTemplate Template:HBA.
- HLA-B15 wikiPageUsesTemplate Template:HLA-B_serotypes.
- HLA-B15 wikiPageUsesTemplate Template:Reflist.
- HLA-B15 subject Category:Drug-sensitivity_genes.
- HLA-B15 subject Category:HLA-B_alleles.
- HLA-B15 hypernym Serotype.
- HLA-B15 type Species.
- HLA-B15 comment "HLA-B15 (B15) is an HLA-B serotype. The serotype identifies the B*15 gene-allele protein products of HLA-B.B15 is a broad antigen can be subdivided into several split antigens that are often used in characterization. These are B62, B63, B70, B71, B72, B75, B76, B77. B*15 is the largest allele grouping for any known human autosomal locus, idenitified as of August 2008 there are more than 150 alleles and ~140 amino acid sequence variants from those gene products.".
- HLA-B15 label "HLA-B15".
- HLA-B15 sameAs m.04glj83.
- HLA-B15 sameAs Q5630078.
- HLA-B15 sameAs Q5630078.
- HLA-B15 wasDerivedFrom HLA-B15?oldid=678849716.
- HLA-B15 depiction HLA_B%5E1501.png.
- HLA-B15 isPrimaryTopicOf HLA-B15.