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- Growth_hormone_receptor abstract "Growth hormone receptor is a protein that in humans is encoded by the GHR gene. GHR orthologs have been identified in most mammals.This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization (the receptor may however also exist as a pre-assembled non-functional dimer ) and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature (proportional dwarfism). Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. Laron mice (that is mice genetically engineered to carry defective Ghr), have a dramatic reduction in body mass (only reaching 50% of the weight of normal siblings), and also show a ~40% increase in lifespan.".
- Growth_hormone_receptor entrezgene "2690".
- Growth_hormone_receptor wikiPageExternalLink gh;jsessionid=38C6FF829262C710E269F048A93E9ECC.
- Growth_hormone_receptor wikiPageExternalLink Page1.htm.
- Growth_hormone_receptor wikiPageExternalLink motm.do?momID=52.
- Growth_hormone_receptor wikiPageID "8429751".
- Growth_hormone_receptor wikiPageLength "14768".
- Growth_hormone_receptor wikiPageOutDegree "26".
- Growth_hormone_receptor wikiPageRevisionID "663266467".
- Growth_hormone_receptor wikiPageWikiLink Acromegaly.
- Growth_hormone_receptor wikiPageWikiLink CISH.
- Growth_hormone_receptor wikiPageWikiLink Carnivore.
- Growth_hormone_receptor wikiPageWikiLink Carnivores.
- Growth_hormone_receptor wikiPageWikiLink Colugo.
- Growth_hormone_receptor wikiPageWikiLink Dermoptera.
- Growth_hormone_receptor wikiPageWikiLink Dimer_(chemistry).
- Growth_hormone_receptor wikiPageWikiLink Felid.
- Growth_hormone_receptor wikiPageWikiLink Felidae.
- Growth_hormone_receptor wikiPageWikiLink Gene.
- Growth_hormone_receptor wikiPageWikiLink Growth_hormone.
- Growth_hormone_receptor wikiPageWikiLink Homology_(biology).
- Growth_hormone_receptor wikiPageWikiLink Janus_kinase_2.
- Growth_hormone_receptor wikiPageWikiLink Laron_syndrome.
- Growth_hormone_receptor wikiPageWikiLink Mammal.
- Growth_hormone_receptor wikiPageWikiLink Mammals.
- Growth_hormone_receptor wikiPageWikiLink Mustelid.
- Growth_hormone_receptor wikiPageWikiLink Mustelidae.
- Growth_hormone_receptor wikiPageWikiLink Nuclear_DNA.
- Growth_hormone_receptor wikiPageWikiLink Orthologs.
- Growth_hormone_receptor wikiPageWikiLink PTPN11.
- Growth_hormone_receptor wikiPageWikiLink Pegvisomant.
- Growth_hormone_receptor wikiPageWikiLink Pituitary_gland.
- Growth_hormone_receptor wikiPageWikiLink Protein.
- Growth_hormone_receptor wikiPageWikiLink Protein-protein_interaction.
- Growth_hormone_receptor wikiPageWikiLink Protein–protein_interaction.
- Growth_hormone_receptor wikiPageWikiLink Receptor_antagonist.
- Growth_hormone_receptor wikiPageWikiLink Rodent.
- Growth_hormone_receptor wikiPageWikiLink Rodentia.
- Growth_hormone_receptor wikiPageWikiLink SGTA.
- Growth_hormone_receptor wikiPageWikiLink Somatostatin.
- Growth_hormone_receptor wikiPageWikiLink Subcutaneous_injection.
- Growth_hormone_receptor wikiPageWikiLink Suppressor_of_cytokine_signaling_1.
- Growth_hormone_receptor wikiPageWikiLink Taxonomic.
- Growth_hormone_receptor wikiPageWikiLink Taxonomy_(biology).
- Growth_hormone_receptor wikiPageWikiLinkText "GH receptor".
- Growth_hormone_receptor wikiPageWikiLinkText "GH-R".
- Growth_hormone_receptor wikiPageWikiLinkText "GHR".
- Growth_hormone_receptor wikiPageWikiLinkText "Growth hormone receptor".
- Growth_hormone_receptor wikiPageWikiLinkText "Growth hormone receptor#Antagonists".
- Growth_hormone_receptor wikiPageWikiLinkText "Growth_hormone_receptor#Antagonists".
- Growth_hormone_receptor wikiPageWikiLinkText "growth hormone receptor".
- Growth_hormone_receptor hasPhotoCollection Growth_hormone_receptor.
- Growth_hormone_receptor requireManualInspection "no".
- Growth_hormone_receptor summaryText "This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome , a disorder characterized by short stature . Other splice variants, including one encoding a soluble form of the protein , have been observed but have not been thoroughly characterized. Laron mice , have a dramatic reduction in body mass , and also show a ~40% increase in lifespan.".
- Growth_hormone_receptor updateCitations "yes".
- Growth_hormone_receptor updatePage "yes".
- Growth_hormone_receptor updateProteinBox "yes".
- Growth_hormone_receptor updateSummary "no".
- Growth_hormone_receptor wikiPageUsesTemplate Template:Cytokine_receptors.
- Growth_hormone_receptor wikiPageUsesTemplate Template:MeshName.
- Growth_hormone_receptor wikiPageUsesTemplate Template:Neuropeptide_receptors.
- Growth_hormone_receptor wikiPageUsesTemplate Template:PBB.
- Growth_hormone_receptor wikiPageUsesTemplate Template:PBB_Controls.
- Growth_hormone_receptor wikiPageUsesTemplate Template:PBB_Summary.
- Growth_hormone_receptor wikiPageUsesTemplate Template:PDB_Gallery.
- Growth_hormone_receptor wikiPageUsesTemplate Template:Peptidergics.
- Growth_hormone_receptor wikiPageUsesTemplate Template:Reflist.
- Growth_hormone_receptor hypernym Protein.
- Growth_hormone_receptor type Biomolecule.
- Growth_hormone_receptor type Protein.
- Growth_hormone_receptor type Thing.
- Growth_hormone_receptor type Q206229.
- Growth_hormone_receptor type Q8054.
- Growth_hormone_receptor comment "Growth hormone receptor is a protein that in humans is encoded by the GHR gene. GHR orthologs have been identified in most mammals.This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization (the receptor may however also exist as a pre-assembled non-functional dimer ) and the activation of an intra- and intercellular signal transduction pathway leading to growth.".
- Growth_hormone_receptor label "Growth hormone receptor".
- Growth_hormone_receptor sameAs Somatotropin-Rezeptor.
- Growth_hormone_receptor sameAs m.0273423.
- Growth_hormone_receptor sameAs Somatotropinski_receptor.
- Growth_hormone_receptor sameAs Somatotropinski_receptor.
- Growth_hormone_receptor sameAs Q2299608.
- Growth_hormone_receptor sameAs Q2299608.
- Growth_hormone_receptor sameAs 生长激素受体.
- Growth_hormone_receptor wasDerivedFrom Growth_hormone_receptor?oldid=663266467.
- Growth_hormone_receptor isPrimaryTopicOf Growth_hormone_receptor.