Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Granisetron> ?p ?o }
- Granisetron abstract "Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.Granisetron was developed by chemists working at the British drug company Beecham around 1988 and is available as a generic. It is produced by Roche Laboratories under the trade name Kytril. The drug was approved in the United Kingdom in 1991 and in United States in 1994 by the FDA.A granisetron transdermal patch with the trade name Sancuso was approved by the US FDA on September 12, 2008. Sancuso is manufactured by 3M Drug Delivery Systems Division in St. Paul, MN, for ProStrakan, Inc., a pharmaceutical company headquartered in Bedminster, NJ, with global headquarters in Scotland.Granisetron is metabolized slowly by the liver, giving it a longer than average half-life. One dose usually lasts 4 to 9 hours and is usually administered once or twice daily. This drug is removed from the body by the liver and kidneys.".
- Granisetron atcPrefix "A04".
- Granisetron atcSuffix "AA02".
- Granisetron bioavailability "60.0".
- Granisetron casNumber "109889-09-0".
- Granisetron chEBI "5537".
- Granisetron drugbank "DB00889".
- Granisetron fdaUniiCode "WZG3J2MCOL".
- Granisetron iupacName "1-methyl-N-((1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide".
- Granisetron pubchem "3510".
- Granisetron thumbnail Granisetron.svg?width=300.
- Granisetron wikiPageExternalLink www.kytril.com.
- Granisetron wikiPageExternalLink www.sancuso.com.
- Granisetron wikiPageID "429616".
- Granisetron wikiPageLength "7376".
- Granisetron wikiPageOutDegree "45".
- Granisetron wikiPageRevisionID "678328495".
- Granisetron wikiPageWikiLink 5-HT3_antagonist.
- Granisetron wikiPageWikiLink 5-HT3_receptor_antagonist:drug_discovery_and_development.
- Granisetron wikiPageWikiLink Antiemetic.
- Granisetron wikiPageWikiLink Beecham_(pharmaceutical_company).
- Granisetron wikiPageWikiLink Beecham_Group.
- Granisetron wikiPageWikiLink Bemesetron.
- Granisetron wikiPageWikiLink Biological_half-life.
- Granisetron wikiPageWikiLink Category:5-HT3_antagonists.
- Granisetron wikiPageWikiLink Category:Amides.
- Granisetron wikiPageWikiLink Category:Antiemetics.
- Granisetron wikiPageWikiLink Category:Cancer_treatments.
- Granisetron wikiPageWikiLink Category:Indazoles.
- Granisetron wikiPageWikiLink Category:Tropanes.
- Granisetron wikiPageWikiLink Chemotherapy.
- Granisetron wikiPageWikiLink Cyclic_vomiting_syndrome.
- Granisetron wikiPageWikiLink Cyclizine.
- Granisetron wikiPageWikiLink Cytochrome_P450.
- Granisetron wikiPageWikiLink Dopamine.
- Granisetron wikiPageWikiLink Droperidol.
- Granisetron wikiPageWikiLink Food_and_Drug_Administration.
- Granisetron wikiPageWikiLink Gastroenteritis.
- Granisetron wikiPageWikiLink Hoffmann-La_Roche.
- Granisetron wikiPageWikiLink Kidney.
- Granisetron wikiPageWikiLink Liver.
- Granisetron wikiPageWikiLink Medulla_oblongata.
- Granisetron wikiPageWikiLink Metoclopramide.
- Granisetron wikiPageWikiLink Muscarinic_acetylcholine_receptor.
- Granisetron wikiPageWikiLink Muscarinic_receptor.
- Granisetron wikiPageWikiLink Nausea.
- Granisetron wikiPageWikiLink Ondansetron.
- Granisetron wikiPageWikiLink Post-operative_nausea_and_vomiting.
- Granisetron wikiPageWikiLink Postoperative_nausea_and_vomiting.
- Granisetron wikiPageWikiLink Ricasetron.
- Granisetron wikiPageWikiLink September_2008.
- Granisetron wikiPageWikiLink Serotonin.
- Granisetron wikiPageWikiLink Transdermal_patch.
- Granisetron wikiPageWikiLink Tropanserin.
- Granisetron wikiPageWikiLink Tropisetron.
- Granisetron wikiPageWikiLink United_Kingdom.
- Granisetron wikiPageWikiLink United_States.
- Granisetron wikiPageWikiLink Vagus_nerve.
- Granisetron wikiPageWikiLink Vomiting.
- Granisetron wikiPageWikiLink Yoshitaka_Fujii.
- Granisetron wikiPageWikiLink Zatosetron.
- Granisetron wikiPageWikiLinkText "Granisetron".
- Granisetron wikiPageWikiLinkText "Kytril".
- Granisetron wikiPageWikiLinkText "granisetron".
- Granisetron atcPrefix "A04".
- Granisetron atcSuffix "AA02".
- Granisetron bioavailability "60.0".
- Granisetron c "18".
- Granisetron casNumber "109889".
- Granisetron chebi "5537".
- Granisetron chembl "519643".
- Granisetron chemspiderid "10482033".
- Granisetron drugbank "DB00889".
- Granisetron eliminationHalfLife "-50400.0".
- Granisetron excretion "Renal 11–12%, faecal 38%".
- Granisetron h "24".
- Granisetron hasPhotoCollection Granisetron.
- Granisetron image "Granisetron_3D.png".
- Granisetron iupacName "1".
- Granisetron iupharLigand "2292".
- Granisetron iupharLigand "2300".
- Granisetron kegg "D04370".
- Granisetron legalAu "S4".
- Granisetron legalUk "POM".
- Granisetron legalUs "Rx-only".
- Granisetron medlineplus "a601211".
- Granisetron metabolism "Hepatic".
- Granisetron molecularWeight "312.41".
- Granisetron n "4".
- Granisetron o "1".
- Granisetron pregnancyAu "B1".
- Granisetron proteinBound "65.0".
- Granisetron pubchem "3510".
- Granisetron routesOfAdministration "Oral, intravenous, transdermal".
- Granisetron smiles "CN4[C@@H]1CCC[C@H]4C[C@H]NCc3nnc2ccccc23".
- Granisetron stdinchi "1".
- Granisetron stdinchikey "MFWNKCLOYSRHCJ-BTTYYORXSA-N".
- Granisetron tradename "Kytril".
- Granisetron unii "WZG3J2MCOL".
- Granisetron verifiedfields "changed".
