Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Glutamate_hypothesis_of_schizophrenia> ?p ?o }
- Glutamate_hypothesis_of_schizophrenia abstract "The glutamate hypothesis of schizophrenia models the subset of pathologic mechanisms linked to glutamatergic signaling. The hypothesis was initially based on a set of clinical, neuropathological, and, later, genetic findings pointing at a hypofunction of glutamatergic signaling via NMDA receptors. While thought to be more proximal to the root causes of schizophrenia, it does not negate the dopamine hypothesis, and the two may be ultimately brought together by circuit-based models. The development of the hypothesis allowed for the integration of the GABAergic and oscillatory abnormalities into the converging disease model and made it possible to discover the causes of some disruptions.Like the dopamine hypothesis, the development of the glutamate hypothesis developed from the observed effects of mind-altering drugs. However, where dopamine agonists can mimic positive symptoms with significant risks to brain structures during and after use, NMDA antagonists mimic some positive and negative symptoms with less brain harm. Likely, both dopaminergic and glutaminergic abnormalities are implicated in schizophrenia, from a profound alteration in the function of the chemical synapses, as well as electrical synaptic irregularities. These form a portion of the complex constellation of factors, neurochemically, psychologically, psychosocially, and structurally, which result in schizophrenia.".
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Antipsychotics.
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cajal-Retzius_cells.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cajal–Retzius_cell.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cannabidiol.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cannabinoid_receptor_1.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cannabinoid_receptor_type_1.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cannabis_(drug).
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Category:Schizophrenia.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Causes_of_schizophrenia.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Cerebral_cortex.
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink ErbB.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Glutamate.
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Olanzapine.
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Raphe_nucleus.
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Schizophrenia.
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- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLink Vasopressin.
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLinkText "Glutamate hypothesis of schizophrenia ".
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLinkText "Glutamate hypothesis of schizophrenia".
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLinkText "Glutamate hypothesis".
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLinkText "glutamate hypothesis of schizophrenia".
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLinkText "glutamate hypothesis".
- Glutamate_hypothesis_of_schizophrenia wikiPageWikiLinkText "glutamatergic mechanisms of schizophrenia".
- Glutamate_hypothesis_of_schizophrenia hasPhotoCollection Glutamate_hypothesis_of_schizophrenia.
- Glutamate_hypothesis_of_schizophrenia wikiPageUsesTemplate Template:Citation_needed.
- Glutamate_hypothesis_of_schizophrenia wikiPageUsesTemplate Template:Cite_journal.
- Glutamate_hypothesis_of_schizophrenia wikiPageUsesTemplate Template:Expert-subject.
- Glutamate_hypothesis_of_schizophrenia wikiPageUsesTemplate Template:Reflist.
- Glutamate_hypothesis_of_schizophrenia subject Category:Schizophrenia.
- Glutamate_hypothesis_of_schizophrenia type Article.
- Glutamate_hypothesis_of_schizophrenia type Article.
- Glutamate_hypothesis_of_schizophrenia comment "The glutamate hypothesis of schizophrenia models the subset of pathologic mechanisms linked to glutamatergic signaling. The hypothesis was initially based on a set of clinical, neuropathological, and, later, genetic findings pointing at a hypofunction of glutamatergic signaling via NMDA receptors. While thought to be more proximal to the root causes of schizophrenia, it does not negate the dopamine hypothesis, and the two may be ultimately brought together by circuit-based models.".
- Glutamate_hypothesis_of_schizophrenia label "Glutamate hypothesis of schizophrenia".
- Glutamate_hypothesis_of_schizophrenia sameAs m.03qhtlh.
- Glutamate_hypothesis_of_schizophrenia sameAs Q5572422.
- Glutamate_hypothesis_of_schizophrenia sameAs Q5572422.