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- Genetics_of_infertility abstract "About 10–15% of human couples are infertile, unable to conceive. In approximately in half of these cases, the underlying cause is related to the male. The underlying causative factors in the male infertility can be attributed to environmental toxins, systemic disorders such as, hypothalamic–pituitary disease, testicular cancers and germ-cell aplasia. Genetic factors including aneuploidies and single-gene mutations are also contributed to the male infertility. Patients suffering from nonobstructive azoospermia or oligozoospermia show microdeletions in the long arm of the Y chromosome and/or chromosomal abnormalities, each with the respective frequency of 9.7% and 13%. A large percentage of human male infertility is estimated to be caused by mutations in genes involved in primary or secondary spermatogenesis and sperm quality and function. Single-gene defects are the focus of most research carried out in this field.NR5A1 mutations are associated with male infertility, suggesting the possibility that these mutations cause the infertility. However, it is possible that these mutations individually have no major effect and only contribute to the male infertility by collaboration with other contributors such as environmental factors and other genomics variants. Vice versa, existence of the other alleles could reduce the phenotypic effects of impaired NR5A1 proteins and attenuate the expression of abnormal phenotypes and manifest male infertility solely.".
- Genetics_of_infertility wikiPageID "47157896".
- Genetics_of_infertility wikiPageLength "8576".
- Genetics_of_infertility wikiPageOutDegree "28".
- Genetics_of_infertility wikiPageRevisionID "682890444".
- Genetics_of_infertility wikiPageWikiLink Ad4BP.
- Genetics_of_infertility wikiPageWikiLink Adrenal_gland_disorder.
- Genetics_of_infertility wikiPageWikiLink Aneuploidy.
- Genetics_of_infertility wikiPageWikiLink Anti-Müllerian_hormone.
- Genetics_of_infertility wikiPageWikiLink Aplasia.
- Genetics_of_infertility wikiPageWikiLink Azoospermia.
- Genetics_of_infertility wikiPageWikiLink Category:Genetics.
- Genetics_of_infertility wikiPageWikiLink Category:Infertility.
- Genetics_of_infertility wikiPageWikiLink Caucasian_race.
- Genetics_of_infertility wikiPageWikiLink Chromosome_9_(human).
- Genetics_of_infertility wikiPageWikiLink Deletion_(genetics).
- Genetics_of_infertility wikiPageWikiLink Genetic_disorder.
- Genetics_of_infertility wikiPageWikiLink Germ_cell.
- Genetics_of_infertility wikiPageWikiLink Germany.
- Genetics_of_infertility wikiPageWikiLink Gonadal_dysgenesis.
- Genetics_of_infertility wikiPageWikiLink Heterozygous.
- Genetics_of_infertility wikiPageWikiLink Hypothalamic_disease.
- Genetics_of_infertility wikiPageWikiLink Hypothalamus.
- Genetics_of_infertility wikiPageWikiLink Infertility.
- Genetics_of_infertility wikiPageWikiLink Karyotype.
- Genetics_of_infertility wikiPageWikiLink Male_infertility.
- Genetics_of_infertility wikiPageWikiLink Microdeletion.
- Genetics_of_infertility wikiPageWikiLink Mullerian_inhibiting_hormone.
- Genetics_of_infertility wikiPageWikiLink NR5A1.
- Genetics_of_infertility wikiPageWikiLink Oligospermia.
- Genetics_of_infertility wikiPageWikiLink Oligozoospermia.
- Genetics_of_infertility wikiPageWikiLink Online_Mendelian_Inheritance_in_Man.
- Genetics_of_infertility wikiPageWikiLink SF1_(gene).
- Genetics_of_infertility wikiPageWikiLink Single-gene_disorder.
- Genetics_of_infertility wikiPageWikiLink Spermatogenesis.
- Genetics_of_infertility wikiPageWikiLink Steroidogenic_factor_1.
- Genetics_of_infertility wikiPageWikiLink Testicular_cancer.
- Genetics_of_infertility wikiPageWikiLink Y_chromosome.
- Genetics_of_infertility wikiPageWikiLink Zygosity.
- Genetics_of_infertility hasPhotoCollection Genetics_of_infertility.
- Genetics_of_infertility wikiPageUsesTemplate Template:Reflist.
- Genetics_of_infertility subject Category:Genetics.
- Genetics_of_infertility subject Category:Infertility.
- Genetics_of_infertility comment "About 10–15% of human couples are infertile, unable to conceive. In approximately in half of these cases, the underlying cause is related to the male. The underlying causative factors in the male infertility can be attributed to environmental toxins, systemic disorders such as, hypothalamic–pituitary disease, testicular cancers and germ-cell aplasia. Genetic factors including aneuploidies and single-gene mutations are also contributed to the male infertility.".
- Genetics_of_infertility label "Genetics of infertility".
- Genetics_of_infertility wasDerivedFrom Genetics_of_infertility?oldid=682890444.
- Genetics_of_infertility isPrimaryTopicOf Genetics_of_infertility.