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- Genetic_architecture abstract "Genetic architecture refers to the underlying genetic basis of a phenotypic trait. A synonymous term is the 'genotype-phenotype map', the way that genotypes lead to the phenotypes.The genotype-phenotype map has been analyzed in terms of several principal axes: epistasis, polygeny, pleiotropy, quasi-continuity, modularity, phenotypic plasticity, robustness, and evolvability. Epistasis: when the alleles at one locus change the phenotypic effects of genetic variation at another locus, the two genes are said to exhibit 'epistasis' in their interactions. Polygeny: when multiple genes contribute to a particular phenotypic character, the map is said to possess 'polygeny'. The genetic architecture in cases of polygeny can be further characterized by the spectrum of contributions of the genes, e.g. many genes of small effect vs. few genes of large effect. Pleiotropy: when multiple phenotypic characters are affected by a single genetic variation, the map is said to possess 'pleiotropy'. Quasi-continuity: when small genetic changes map to small phenotypic changes, the map is said to possess "quasi-continuity" (Lewontin). Modularity: when two different phenotypic characters can be mapped to mostly non-overlapping sets of genes, the map is said to possess 'modularity', though this concept is still in flux in the scientific literature. Plasticity: when a single genotype gives rise to a spectrum of phenotypes, the phenotype is said to have 'plasticity'. The plasticity may occur as different phenotypes among different individuals of the same genotype, or different phenotypes within the lifetime of a single individual, or different phenotypes in response to specific environmental conditions. Mutational robustness: when the same phenotype occurs in an organism despite a variety of environmental perturbations, it is said to be 'robust'. When the same phenotype is produced despite mutations in the genes involved it its production, it is said to possess 'mutational robustness'. Evolvability: when there is a significant chance that genetic variation can be produced which produces a net increase in adaptation in an organism, the genotype-phenotype map is said to have 'evolvability'. Transgressive phenotype: when a phenotype is more extreme than the phenotype displayed by either of the parental lines.".
- Genetic_architecture wikiPageID "1505166".
- Genetic_architecture wikiPageLength "2727".
- Genetic_architecture wikiPageOutDegree "24".
- Genetic_architecture wikiPageRevisionID "679074445".
- Genetic_architecture wikiPageWikiLink Allele.
- Genetic_architecture wikiPageWikiLink Alleles.
- Genetic_architecture wikiPageWikiLink Category:Genetics.
- Genetic_architecture wikiPageWikiLink Epistasis.
- Genetic_architecture wikiPageWikiLink Evolvability.
- Genetic_architecture wikiPageWikiLink Genetic_correlation.
- Genetic_architecture wikiPageWikiLink Genotype.
- Genetic_architecture wikiPageWikiLink Lewontin.
- Genetic_architecture wikiPageWikiLink Locus_(genetics).
- Genetic_architecture wikiPageWikiLink Modularity.
- Genetic_architecture wikiPageWikiLink Mutational_robustness.
- Genetic_architecture wikiPageWikiLink Phenotype.
- Genetic_architecture wikiPageWikiLink Phenotypic_plasticity.
- Genetic_architecture wikiPageWikiLink Phenotypic_trait.
- Genetic_architecture wikiPageWikiLink Pleiotropy.
- Genetic_architecture wikiPageWikiLink Polygene.
- Genetic_architecture wikiPageWikiLink Richard_Lewontin.
- Genetic_architecture wikiPageWikiLink Robustness_(evolution).
- Genetic_architecture wikiPageWikiLink Trait_(biological).
- Genetic_architecture wikiPageWikiLink Transgressive_phenotype.
- Genetic_architecture wikiPageWikiLink Transgressive_segregation.
- Genetic_architecture wikiPageWikiLinkText "Genetic architecture".
- Genetic_architecture wikiPageWikiLinkText "genetic architecture".
- Genetic_architecture auto "yes".
- Genetic_architecture date "December 2009".
- Genetic_architecture hasPhotoCollection Genetic_architecture.
- Genetic_architecture wikiPageUsesTemplate Template:Genarch.
- Genetic_architecture wikiPageUsesTemplate Template:Genetics-stub.
- Genetic_architecture wikiPageUsesTemplate Template:Unreferenced.
- Genetic_architecture subject Category:Genetics.
- Genetic_architecture type Article.
- Genetic_architecture type Article.
- Genetic_architecture comment "Genetic architecture refers to the underlying genetic basis of a phenotypic trait. A synonymous term is the 'genotype-phenotype map', the way that genotypes lead to the phenotypes.The genotype-phenotype map has been analyzed in terms of several principal axes: epistasis, polygeny, pleiotropy, quasi-continuity, modularity, phenotypic plasticity, robustness, and evolvability.".
- Genetic_architecture label "Genetic architecture".
- Genetic_architecture sameAs Arquitetura_genética.
- Genetic_architecture sameAs m.056k1k.
- Genetic_architecture sameAs Q5532883.
- Genetic_architecture sameAs Q5532883.
- Genetic_architecture wasDerivedFrom Genetic_architecture?oldid=679074445.
- Genetic_architecture isPrimaryTopicOf Genetic_architecture.