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- Gene_isoform abstract "Gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or untranslated regions (UTRs), potentially altering gene function.Cis-regulatory elements in the promoter contain sequences recognized by transcription factors and the basal transcription machinery. So the location of the TSS is important for understanding the biogenesis of specific isoforms.The idea that different binding partners confer different functional properties has been well studied in tissue-specific gene regulation. For example, the same transcription factor (TF) can direct gene expression in different tissues simply by binding with different TFs in each tissue. Isoforms harboring changes in the CDS have been the most thoroughly characterized because they commonly give rise to proteins with different functional properties. UTRs regulate the levels of primary transcript in numerous ways: transcript stability, folding and turnover, as well as translation efficiency. UTRs are often the target of miRNA, which typically downregulate transcript expression by triggering degradation or halting translation.The gene isoforms can be sequenced by Whole Transcriptome Shotgun Sequencing (RNA-Seq). Recently some progress has been made to characterize known isoforms of regeneration associated genes (RAGs) using RNA-Seq, which is important in understanding the isoform diversity in the CNS.".
- Gene_isoform wikiPageID "34905782".
- Gene_isoform wikiPageLength "7812".
- Gene_isoform wikiPageOutDegree "15".
- Gene_isoform wikiPageRevisionID "601883496".
- Gene_isoform wikiPageWikiLink ATF3.
- Gene_isoform wikiPageWikiLink Category:RNA.
- Gene_isoform wikiPageWikiLink Cis-Regulatory_element.
- Gene_isoform wikiPageWikiLink Cis-regulatory_element.
- Gene_isoform wikiPageWikiLink Coding_region.
- Gene_isoform wikiPageWikiLink Corticospinal_tract.
- Gene_isoform wikiPageWikiLink Dorsal_root_ganglia.
- Gene_isoform wikiPageWikiLink Dorsal_root_ganglion.
- Gene_isoform wikiPageWikiLink Gene.
- Gene_isoform wikiPageWikiLink MiRNA.
- Gene_isoform wikiPageWikiLink MicroRNA.
- Gene_isoform wikiPageWikiLink PTEN_(gene).
- Gene_isoform wikiPageWikiLink Pyramidal_tracts.
- Gene_isoform wikiPageWikiLink RNA-Seq.
- Gene_isoform wikiPageWikiLink Retinal_ganglion_cell.
- Gene_isoform wikiPageWikiLink Retinal_ganglion_cells.
- Gene_isoform wikiPageWikiLink Three_prime_untranslated_region.
- Gene_isoform wikiPageWikiLink Transcription_(genetics).
- Gene_isoform wikiPageWikiLink Transcription_factor.
- Gene_isoform wikiPageWikiLink Transcription_start_site.
- Gene_isoform wikiPageWikiLink Untranslated_region.
- Gene_isoform wikiPageWikiLinkText "isoform".
- Gene_isoform hasPhotoCollection Gene_isoform.
- Gene_isoform wikiPageUsesTemplate Template:Orphan.
- Gene_isoform wikiPageUsesTemplate Template:Reflist.
- Gene_isoform subject Category:RNA.
- Gene_isoform hypernym MRNAs.
- Gene_isoform comment "Gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or untranslated regions (UTRs), potentially altering gene function.Cis-regulatory elements in the promoter contain sequences recognized by transcription factors and the basal transcription machinery.".
- Gene_isoform label "Gene isoform".
- Gene_isoform sameAs m.0j451ds.
- Gene_isoform sameAs Q5531554.
- Gene_isoform sameAs Q5531554.
- Gene_isoform wasDerivedFrom Gene_isoform?oldid=601883496.
- Gene_isoform isPrimaryTopicOf Gene_isoform.